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A high degree of structural complexity arises in dynamic neuronal dendrites due to extensive branching patterns and diverse spine morphologies, which enable the nervous system to adjust function, construct complex input pathways and thereby…

软凝聚态物质 · 物理学 2026-03-04 Fabian H. Kreten , Barbara A. Niemeyer , Ludger Santen , Reza Shaebani

Aging, the dependence of the dynamics of a physical process on the time $t_a$ since its original preparation, is observed in systems ranging from the motion of charge carriers in amorphous semiconductors over the blinking dynamics of…

统计力学 · 物理学 2014-12-24 Henning Kruesemann , Aljaz Godec , Ralf Metzler

We consider a leaky integrate-and-fire neuron with deterministic subthreshold dynamics and a firing threshold that evolves as an Ornstein-Uhlenbeck process. The formulation of this minimal model is motivated by the experimentally observed…

神经元与认知 · 定量生物学 2015-05-12 Wilhelm Braun , Paul C. Matthews , Rüdiger Thul

We study the dynamics of molecular motor-driven transport into dendritic spines, which are bulbous intracellular compartments in neurons that play a key role in transmitting signals between neurons. We further develop a stochastic model of…

亚细胞过程 · 定量生物学 2025-10-27 Youngmin Park , Thomas G. Fai

Applications of first passage times in stochastic processes arise across a wide range of length and time scales in biological settings. After an initial technical overview, we survey representative applications and their corresponding…

统计力学 · 物理学 2026-05-12 Tom Chou , Maria R. D'Orsogna

The presence of temporal correlations in random movement trajectories is a widespread phenomenon across biological, chemical and physical systems. The ubiquity of persistent and anti-persistent motion in many natural and synthetic systems…

统计力学 · 物理学 2024-07-03 Daniel Marris , Luca Giuggioli

Quantifying how spatial disorder affects the movement of a diffusing particle or agent is fundamental to target search studies. When diffusion occurs on a network, that is on a highly disordered environment, we lack the mathematical tools…

统计力学 · 物理学 2025-08-15 Daniel Marris , Chittaranjan Hens , Subrata Ghosh , Luca Giuggioli

We study the first passage dynamics of an ageing stochastic process in the continuous time random walk (CTRW) framework. In such CTRW processes the test particle performs a random walk, in which successive steps are separated by random…

统计力学 · 物理学 2015-04-08 Henning Krusemann , Aljaz Godec , Ralf Metzler

First passage time plays a fundamental role in dynamical characterization of stochastic processes. Crucially, our current understanding on the problem is almost entirely relies on the theoretical formulations, which assume the processes…

统计力学 · 物理学 2023-02-01 Yuta Sakamoto , Takahiro Sakaue

The transport properties of discrete-time random walks on ring networks with deterministic shortcuts are investigated through analytical and numerical methods. The network consists of a periodic chain where each node is connected to its…

统计力学 · 物理学 2026-04-30 Oscar Ivan Torres Mena , Francisco J Sevilla

We introduce and investigate the escape problem for random walkers that may eventually die, decay, bleach, or lose activity during their diffusion towards an escape or reactive region on the boundary of a confining domain. In the case of a…

化学物理 · 物理学 2020-01-03 D. S. Grebenkov , J. -F. Rupprecht

The spatiotemporal stochastic dynamics of the voltage as well as the upcrossing rate are derived for a model neuron comprising a long dendrite with uniformly distributed filtered excitatory and inhibitory synaptic drive. A cascade of…

神经元与认知 · 定量生物学 2023-04-18 Robert P Gowers , Magnus J E Richardson

We present a unified framework for first-passage time and residence time of random walks in finite one-dimensional disordered biased systems. The derivation is based on exact expansion of the backward master equation in cumulants. The…

统计力学 · 物理学 2009-11-07 Pedro A. Pury , Manuel O. Caceres

The first passage times for enzymatic turnovers in non-equilibrium steady state display a statistical symmetry property related to non-equilibrium fluctuation theorems, that makes it possible to extract the chemical driving force from…

生物物理 · 物理学 2008-12-10 Martin Lindén

First passage of stochastic processes under resetting has recently been an active research topic in the field of statistical physics. However, most of previous studies mainly focused on the systems with continuous time and space. In this…

统计力学 · 物理学 2022-08-30 Hanshuang Chen , Guofeng Li , Feng Huang

Motivated by the dynamics of resonant neurons we consider a differentiable, non-Markovian random process $x(t)$ and particularly the time after which it will reach a certain level $x_b$. The probability density of this first passage time is…

统计力学 · 物理学 2009-11-11 T. Verechtchaguina , I. M. Sokolov , L. Schimansky-Geier

Interesting theoretical problems of target search or threshold crossing, formally known as {\it first passage}, often arise in both diffusive transport problems as well as problems of chemical reaction kinetics. We study three systems…

统计力学 · 物理学 2025-10-22 Hillol Kumar Barman , Pathik Das , Syed Yunus Ali

We theoretically study the trapping time distribution and the efficiency of the excitation energy transport in dendritic systems. Trapping of excitations, created at the periphery of the dendrimer, on a trap located at its core, is used as…

材料科学 · 物理学 2007-05-23 Dirk-Jan Heijs , Victor A. Malyshev , Jasper Knoester

How long a stochastic process survives before leaving a domain depends not only on its intrinsic dynamics but also on how it is observed. Classical first-passage theory assumes continuous monitoring with absorbing boundaries…

数学物理 · 物理学 2025-10-14 Lars Fritz

We study the first-passage properties of a jump process with constant drift where jump amplitudes and inter-arrival times follow arbitrary light-tailed distributions with smooth densities. Using a mapping to an effective discrete-time…

统计力学 · 物理学 2026-03-25 Ivan N. Burenev
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