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Providing an analytical treatment to the stochastic feature of neurons' dynamics is one of the current biggest challenges in mathematical biology. The noisy leaky integrate-and-fire model and its associated Fokker-Planck equation are…

神经元与认知 · 定量生物学 2015-12-14 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

The response of a neural cell to an external stimulus can follow one of the two patterns: Nonresonant neurons monotonously relax to the resting state after excitation while resonant ones show subthreshold oscillations. We investigate how do…

神经元与认知 · 定量生物学 2009-11-10 T. Verechtchaguina , L. Schimansky-Geier , I. M. Sokolov

Stochastic dynamical systems provide essential mathematical frameworks for modeling complex real-world phenomena. The Fokker-Planck-Kolmogorov (FPK) equation governs the evolution of probability density functions associated with stochastic…

统计计算 · 统计学 2025-10-13 Yi Zhang , Yiting Duan , Xiangjun Wang , Zhikun Zhang

The spatiotemporal stochastic dynamics of the voltage as well as the upcrossing rate are derived for a model neuron comprising a long dendrite with uniformly distributed filtered excitatory and inhibitory synaptic drive. A cascade of…

神经元与认知 · 定量生物学 2023-04-18 Robert P Gowers , Magnus J E Richardson

Stochastic resonance is a non-linear phenomenon, in which the sensitivity of signal detectors can be enhanced by adding random noise to the detector input. Here, we demonstrate that noise can also improve the information flux in recurrent…

神经元与认知 · 定量生物学 2018-11-30 Patrick Krauss , Karin Prebeck , Achim Schilling , Claus Metzner

Neurons display spontaneous spiking (in the absence of stimulus signals) as well as a characteristic response to time-dependent external stimuli. In a simple but important class of stochastic neuron models, the integrate-and-fire model with…

神经元与认知 · 定量生物学 2025-03-11 Kolja Klett , Benjamin Lindner

We investigate the fluctuating incompressible Navier--Stokes equation driven by spatially correlated thermal noise characterized by a single length scale. This formulation is constructed to preserve thermal equilibrium through the…

生物物理 · 物理学 2025-11-19 Sijie Huang , Ayush Saurabh , Steve Presse

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

神经元与认知 · 定量生物学 2017-07-20 Guillem Via

Starting from the morphological-functional assumption of the fractal brain, a mathematical model is given by activating brain non-differentiable dynamics through the determinism-nondeterminism inference of the responsible mechanisms. The…

神经元与认知 · 定量生物学 2015-11-18 Maricel Agop , Alina Gavrilut , Gabriel Crumpei , Mitica Craus , Vlad Birlescu

One of the major challenges in neuroscience is to determine how noise that is present at the molecular and cellular levels affects dynamics and information processing at the macroscopic level of synaptically coupled neuronal populations.…

无序系统与神经网络 · 物理学 2014-06-12 Paul C. Bressloff , Jay M. Newby

Biological neurons have adaptive nature and perform complex computations involving the filtering of redundant information. However, most common neural cell models, including biologically plausible, such as Hodgkin-Huxley or Izhikevich, do…

神经元与认知 · 定量生物学 2021-06-22 Oleg Nikitin , Olga Lukyanova , Alex Kunin

Cells sense their surrounding by employing intracellular signaling pathways that transmit hormonal signals from the cell membrane to the nucleus. TGF-$\beta$/SMAD signaling encodes various cell fates, controls tissue homeostasis and is…

Identification of nonlinear dynamical systems is crucial across various fields, facilitating tasks such as control, prediction, optimization, and fault detection. Many applications require methods capable of handling complex systems while…

机器学习 · 统计学 2024-11-05 Luc Brogat-Motte , Riccardo Bonalli , Alessandro Rudi

In dilute turbulent particle-laden flows, such as atmospheric dispersion of pollutants or virus particles, the dynamics of tracer-like to low inertial particles are significantly altered by the fluctuating motion of the carrier fluid phase.…

流体动力学 · 物理学 2024-06-19 Josh Williams , Uwe Wolfram , Ali Ozel

We consider stochastic model based on the linear stochastic differential equation with the linear relaxation and with the diffusion-like fluctuations of the relaxation rate. The model generates monofractal signals with the non-Gaussian…

数据分析、统计与概率 · 物理学 2015-05-18 B. Kaulakys , M. Alaburda , J. Ruseckas

We present an explicit unified stochastic model of fluctuations in population size due to random birth, death, density-dependent competition and environmental fluctuations. Stochastic dynamics provide insight into small populations,…

种群与进化 · 定量生物学 2008-07-31 Alexei J. Drummond , Peter D. Drummond

Bottom-up models of functionally relevant patterns of neural activity provide an explicit link between neuronal dynamics and computation. A prime example of functional activity pattern is hippocampal replay, which is critical for memory…

神经元与认知 · 定量生物学 2024-09-30 Bastian Pietras , Valentin Schmutz , Tilo Schwalger

Stochasticity is both exploited and controlled by cells. Although the intrinsic stochasticity inherent in biochemistry is relatively well understood, cellular variation, or 'noise', is predominantly generated by interactions of the system…

分子网络 · 定量生物学 2008-09-18 Vahid Shahrezaei , Julien F Ollivier , Peter S Swain

We consider potential type dynamical systems in finite dimensions with two meta-stable states. They are subject to two sources of perturbation: a slow external periodic perturbation of period $T$ and a small Gaussian random perturbation of…

概率论 · 数学 2007-05-23 Samuel Herrmann , Peter Imkeller , Dierk Peithmann

We investigate the stochastic resonance phenomenon in a physical system based on a tunnel diode. The experimental control parameters are set to allow the control of the frequency and amplitude of the deterministic modulating signal over an…

统计力学 · 物理学 2009-10-31 Rosario N. Mantegna , Bernardo Spagnolo , Marco Trapanese