相关论文: Hybrid models for simulating blood flow in microva…

In this article an upscaled model is presented, for complex networks with highly clustered regions exchanging some abstract quantities in both, microscale and macroscale level. Such an intricate system is approximated by a partitioned open…

Within animals, oxygen exchange occurs within networks containing potentially billions of microvessels that are distributed throughout the animal's body. Innovative imaging methods now allow for mapping of the architecture and blood flows…

The objective of this study is to highlight the effect of porosity variation in a topology optimization process in the field of fluid dynamics. Usually a penalization term added to momentum equation provides to get material distribution.…

A new numerical scheme is proposed for flow computation in complex discrete fracture networks. The method is based on a three-field formulation of the Darcy law for the description of the hydraulic head on the fractures and uses a cost…

We study the flow of a micropolar fluid in a thin domain with microstructure, i.e. a thin domain with thickness $\varepsilon$ which is perforated by periodically distributed solid cylinders of size $a_\varepsilon$. A main feature of this…

Cerebral autoregulation plays a key physiological role by limiting blood flow changes in the face of pressure fluctuations. Although the involved cellular processes are mechanically driven, the quantification of haemodynamic forces in…

This paper introduces a new discrete fracture model accounting for non-isothermal compositional multiphase Darcy flows and complex networks of fractures with intersecting, immersed and non immersed fractures. The so called…

Water flow in plant tissues takes place in two different physical domains separated by semipermeable membranes: cell insides and cell walls. The assembly of all cell insides and cell walls are termed symplast and apoplast, respectively.…

The novel neural networks show great potential in solving partial differential equations. For single-phase flow problems in subsurface porous media with high-contrast coefficients, the key is to develop neural operators with accurate…

The flow of cerebrospinal fluid through the perivascular spaces of the brain is believed to play a crucial role in eliminating toxic waste proteins. While the driving forces of this flow have been enigmatic, experiments have shown that…

We analyse mathematical models in order to understand how microstructural features of vascular networks may affect blood-flow dynamics, and to identify particular characteristics that promote the onset of self-sustained oscillations. By…

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Many numerical studies of blood flow impose a rigid wall assumption due to the simplicity of its implementation compared to a full coupling to a solid mechanics model. In this paper, we present a localised method for incorporating the…

The goal of this paper is to investigate the validity of a hybrid embedded/homogenized in-silico approach for modeling perfusion through solid tumors. The rationale behind this novel idea is that only the larger blood vessels have to be…

In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…

Direct numerical simulations (DNS) indicate that at large values of the Rayleigh number ($Ra$) convection in porous media self-organizes into narrowly-spaced columnar flows, with more complex spatiotemporal features being confined to…

In porous media, there are three known regimes of fluid flows, namely, pre-Darcy, Darcy and post-Darcy. Because of their different natures, these are usually treated separately in literature. To study complex flows when all three regimes…

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

The effect of a network of fixed rigid fibers on fluid flow is investigated by means of three-dimensional direct numerical simulations using an immersed boundary method for the fluid-structure coupling. Different flows are considered (i.e.,…

Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like…