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Neurodegeneration affects cortical gray matter leading to loss of cortical mantle volume. As a result of such volume loss, the geometrical arrangement of the regions on the cortical surface is expected to be altered in comparison to healthy…

神经元与认知 · 定量生物学 2016-11-16 Amanmeet Garg , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

Graph theory has drawn a lot of attention in the field of Neuroscience during the last decade, mainly due to the abundance of tools that it provides to explore the interactions of elements in a complex network like the brain. The local and…

神经元与认知 · 定量生物学 2016-11-16 Sofia Ira Ktena , Sarah Parisot , Jonathan Passerat-Palmbach , Daniel Rueckert

The standard cosmological model with cold dark matter posits a hierarchical formation of structures. We introduce topological neural networks (TNNs), implemented as message-passing neural networks on higher-order structures, to effectively…

宇宙学与河外天体物理 · 物理学 2025-08-06 Jun-Young Lee , Francisco Villaescusa-Navarro

The study of the topological structure of complex networks has fascinated researchers for several decades, and today we have a fairly good understanding of the types and reoccurring characteristics of many different complex networks.…

社会与信息网络 · 计算机科学 2014-06-23 Matthieu Roy , Stefan Schmid , Gilles Trédan

Let P be a distribution with support S. The salient features of S can be quantified with persistent homology, which summarizes topological features of the sublevel sets of the distance function (the distance of any point x to S). Given a…

In this paper we present an approach to determine the smallest possible number of neurons in a layer of a neural network in such a way that the topology of the input space can be learned sufficiently well. We introduce a general procedure…

机器学习 · 统计学 2026-03-24 Luciano Melodia , Richard Lenz

Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…

图像与视频处理 · 电气工程与系统科学 2021-10-28 Haotian Wang , Min Xian , Aleksandar Vakanski

fMRI is a unique non-invasive approach for understanding the functional organization of the human brain, and task-based fMRI promotes identification of functionally relevant brain regions associated with a given task. Here, we use fMRI…

神经元与认知 · 定量生物学 2019-02-06 A. Yamin , M. Dayan , L. Squarcina , P. Brambilla , V. Murino , V. Diwadkar , D. Sona

Characterization of joint probability distribution for large networks of random variables remains a challenging task in data science. Probabilistic graph approximation with simple topologies has practically been resorted to; typically the…

数据结构与算法 · 计算机科学 2024-04-10 Fereshteh R. Dastjerdi , Liming Cai

Modeling the associations between real world entities from their multivariate cross-sectional profiles can provide cues into the concerted working of these entities as a system. Several techniques have been proposed for deciphering these…

机器学习 · 计算机科学 2025-01-07 Radha Nagarajan , Marco Scutari

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

神经元与认知 · 定量生物学 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Modeling and topological analysis of networks in biological and other complex systems, must venture beyond the limited consideration of very few network metrics like degree, betweenness or assortativity. A proper identification of…

定量方法 · 定量生物学 2012-09-25 Soumen Roy

Distance measures play an important role in shape classification and data analysis problems. Topological distances based on Reeb graphs and persistence diagrams have been employed to obtain effective algorithms in shape matching and scalar…

机器学习 · 计算机科学 2023-03-07 Yashwanth Ramamurthi , Amit Chattopadhyay

Persistence diagrams (PDs) play a key role in topological data analysis (TDA), in which they are routinely used to describe topological properties of complicated shapes. PDs enjoy strong stability properties and have proven their utility in…

计算几何 · 计算机科学 2017-11-10 Mathieu Carrière , Marco Cuturi , Steve Oudot

This paper develops fundamental limits of deep neural network learning by characterizing what is possible if no constraints are imposed on the learning algorithm and on the amount of training data. Concretely, we consider Kolmogorov-optimal…

机器学习 · 计算机科学 2021-03-15 Dennis Elbrächter , Dmytro Perekrestenko , Philipp Grohs , Helmut Bölcskei

The loss surface of deep neural networks has recently attracted interest in the optimization and machine learning communities as a prime example of high-dimensional non-convex problem. Some insights were recently gained using spin glass…

机器学习 · 统计学 2017-06-05 C. Daniel Freeman , Joan Bruna

Many community detection algorithms require the introduction of a measure on the set of nodes. Previously, a lot of efforts have been made to find the top-performing measures. In most cases, experiments were conducted on several datasets or…

社会与信息网络 · 计算机科学 2021-11-03 Rinat Aynulin

Traditional Topological Data Analysis (TDA) methods, such as Persistent Homology (PH), rely on distance measures (e.g., cross-correlation, partial correlation, coherence, and partial coherence) that are symmetric by definition. While useful…

神经元与认知 · 定量生物学 2024-07-19 Anass B. El-Yaagoubi , Moo K. Chung , Hernando Ombao

Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

神经元与认知 · 定量生物学 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

Solving topological grid puzzles requires reasoning over global spatial invariants such as connectivity, loop closure, and region symmetry and remains challenging for even the most powerful large language models (LLMs). To study these…