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The aftermath of the Covid-19 pandemic saw more severe outcomes for racial minority groups and economically-deprived communities. Such disparities can be explained by several factors, including unequal access to healthcare, as well as the…

计算机与社会 · 计算机科学 2024-03-12 Nicola Neophytou , Afaf Taïk , Golnoosh Farnadi

We consider a SIR model with temporary immunity and time dependent transmission rate. We assume time dependent vaccination which confers the same immunity as natural infection. We study two types of vaccination strategies: i) optimal…

种群与进化 · 定量生物学 2016-04-06 Paulo Doutor , Paula Rodrigues , Maria do Céu Soares , Fabio A. C. C. Chalub

We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. Applying the Pontryagin's…

最优化与控制 · 数学 2017-06-15 Luca Bolzoni , Elena Bonacini , Cinzia Soresina , Maria Groppi

In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

概率论 · 数学 2018-02-15 Carolina Fransson , Pieter Trapman

In this paper, we propose a two-group SIR epidemic model to simulate the outcome of stay-at-home policy and wearing face masks during the first COVID-19 epidemic wave in the United States. Based on our proposed model, we further use the…

种群与进化 · 定量生物学 2021-01-11 Jun Liu , Xiang-Sheng Wang

We consider the problem of the optimal allocation of vaccination and protection measures for the Susceptible-Infected-Recovered-Infected (SIRI) epidemiological model, which generalizes the classical Susceptible-Infected-Recovered (SIR) and…

最优化与控制 · 数学 2025-05-09 Urmee Maitra , Ashish R. Hota , Rohit Gupta , Alfred O. Hero

To mitigate the pandemic stemming from COVID-19, numerous nations have initiated extensive vaccination campaigns for their citizens since late 2020. While affluent countries have predominantly received vaccine allocations, fewer doses have…

物理与社会 · 物理学 2024-04-01 Hsin-Ju Chou , Jing-Yuan Ko , Sung-Po Chao

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

种群与进化 · 定量生物学 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, in many low and middle-income countries with geographically dispersed and nomadic populations, last-mile vaccine delivery can be extremely…

应用统计 · 统计学 2021-04-30 Yuwen Yang , Jayant Rajgopal

We consider a susceptible, infected, and recovered infectious disease model which incorporates a vaccination rate. In particular, we study the problem of choosing the vaccination rate in order to reduce the number of infected individuals to…

偏微分方程分析 · 数学 2021-08-30 Ryan Hynd , Dennis Ikpe , Terrance Pendleton

Understanding the dynamics of an epidemic spread is crucial for effective control measures. During the COVID-19 pandemic, quarantines were implemented to minimize infections while mitigating social and economic impacts, raising the question…

统计力学 · 物理学 2024-11-19 Eyal Atias , Michael Assaf

We consider the interplay of vaccination and migration rates on disease persistence in epidemiological systems. We show that short-term and long-term migration can inhibit disease persistence. As a result, we show how migration changes how…

生物物理 · 物理学 2012-05-22 Jackson Burton , Lora Billings , Derek A. T. Cummings , Ira B. Schwartz

We formalize and study the problem of optimal allocation strategies for a (perfect) vaccine in the infinite-dimensional SIS model. The question may be viewed as a bi-objective minimization problem, where one tries to minimize simultaneously…

概率论 · 数学 2021-08-27 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

In this paper, we study the problem of minimizing the spread of a viral epidemic when immunization takes a non-negligible amount of time to take into effect. Specifically, our problem is to determine which set of nodes to be vaccinated when…

社会与信息网络 · 计算机科学 2023-07-14 Shiju Li , Xin Huang , Chul-Ho Lee , Do Young Eun

How to strategically allocate the available vaccines is a crucial issue for pandemic control. In this work, we propose a mathematical framework for optimal stabilizing vaccine allocation, where our goal is to send the infections to zero as…

最优化与控制 · 数学 2021-09-13 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

The SEIRS model, an extension of the SEIR model for analyzing and predicting the spread of virus infection, was further extended to consider the movement of people across regions. In contrast to previous models that con-sider the risk of…

医学物理 · 物理学 2021-07-01 Yukio Ohsawa , Teruaki Hayashi , Sae Kondo

We propose a versatile model with a flexible choice of control for an early-pandemic outbreak prevention when vaccine/drug is not yet available. At that stage, control is often limited to non-medical interventions like social distancing and…

最优化与控制 · 数学 2024-06-14 Alexandra Smirnova , Xiaojing Ye

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

种群与进化 · 定量生物学 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

The paper uses machine learning and mathematical modeling to predict future vaccine distribution and solve the problem of allocating vaccines to different types of hospitals. They collected data and analyzed it, finding factors such as…

计算机与社会 · 计算机科学 2023-06-13 Baiqiao Yin , Jiaqing Yuan , Weichen Lv , Jiehui Huang , Guian Fang

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

系统与控制 · 电气工程与系统科学 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise