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Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

机器学习 · 统计学 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

1. Predicting space use patterns of animals from their interactions with the environment is fundamental for understanding the effect of habitat changes on ecosystem functioning. Recent attempts to address this problem have sought to unify…

We propose an algorithm for the efficient and robust sampling of the posterior probability distribution in Bayesian inference problems. The algorithm combines the local search capabilities of the Manifold Metropolis Adjusted Langevin…

Phylogenetic and discrete-trait evolutionary inference depend heavily on an appropriate characterization of the underlying character substitution process. In this paper, we present random-effects substitution models that extend common…

Seemingly unrelated regression is a natural framework for regressing multiple correlated responses on multiple predictors. The model is very flexible, with multiple linear regression and covariance selection models being special cases.…

统计方法学 · 统计学 2019-07-23 Yunfan Li , Jyotishka Datta , Bruce A. Craig , Anindya Bhadra

Traditional epidemic detection algorithms make decisions using only local information. We propose a novel approach that explicitly models spatial information fusion from several metapopulations. Our method also takes into account…

统计计算 · 统计学 2015-09-15 Michael Ludkovski , Katherine Shatskikh

Dynamical modelling is central to many scientific domains, including pharmacometrics, systems biology, physiology, and epidemiology. In these settings, heterogeneity is often intrinsic: different subjects or units follow related but…

机器学习 · 计算机科学 2026-05-14 Julien Martinelli , Maksim Sinelnikov , Harri Lähdesmäki , Quentin Clairon , Mélanie Prague

Indirect information on population size, like pellet counts or volunteer counts, is the main source of information in most ecological studies and applied population management situations. Often, such observations are treaded as if they were…

应用统计 · 统计学 2016-09-27 Jonas Wallin , Kjell Wallin

The aim of this work is to learn models of population dynamics of physical systems that feature stochastic and mean-field effects and that depend on physics parameters. The learned models can act as surrogates of classical numerical models…

机器学习 · 统计学 2024-10-28 Jules Berman , Tobias Blickhan , Benjamin Peherstorfer

Survival models are used to analyze time-to-event data in a variety of disciplines. Proportional hazard models provide interpretable parameter estimates, but proportional hazards assumptions are not always appropriate. Non-parametric models…

统计方法学 · 统计学 2022-07-08 Richard D. Payne , Nilabja Guha , Bani K. Mallick

Traditionally, frequency dependent evolutionary dynamics is described by deterministic replicator dynamics assuming implicitly infinite population sizes. Only recently have stochastic processes been introduced to study evolutionary dynamics…

统计力学 · 物理学 2007-05-23 Arne Traulsen , Jens Christian Claussen , Christoph Hauert

One's ability to learn a generative model of the world without supervision depends on the extent to which one can construct abstract knowledge representations that generalize across experiences. To this end, capturing an accurate…

机器学习 · 计算机科学 2021-10-28 Zahra Sheikhbahaee , Dongshu Luo , Blake VanBerlo , S. Alex Yun , Adam Safron , Jesse Hoey

This paper deals with the nonparametric estimation in heteroscedastic regression $ Y_i=f(X_i)+\xi_i, \: i=1,...,n $, with incomplete information, i.e. each real random variable $ \xi_i $ has a density $ g_{i} $ which is unknown to the…

统计理论 · 数学 2011-05-10 Michaël Chichignoud

We investigate the frequentist properties of Bayesian procedures for estimation based on the horseshoe prior in the sparse multivariate normal means model. Previous theoretical results assumed that the sparsity level, that is, the number of…

统计理论 · 数学 2017-02-14 Stéphanie van der Pas , Botond Szabó , Aad van der Vaart

To study population dynamics, ecologists and wildlife biologists use relative abundance data, which are often subject to temporal preferential sampling. Temporal preferential sampling occurs when sampling effort varies across time. To…

统计方法学 · 统计学 2022-12-14 Michael R. Schwob , Mevin B. Hooten , Travis McDevitt-Galles

We present a Bayesian method for characterizing the mating system of populations reproducing through a mixture of self-fertilization and random outcrossing. Our method uses patterns of genetic variation across the genome as a basis for…

Increasingly complex datasets pose a number of challenges for Bayesian inference. Conventional posterior sampling based on Markov chain Monte Carlo can be too computationally intensive, is serial in nature and mixes poorly between posterior…

机器学习 · 统计学 2019-08-27 Edwin Fong , Simon Lyddon , Chris Holmes

Within the framework of population genetics we consider the evolution of an asexual haploid population under the effect of a rapidly varying natural selection (microevolution). We focus on the case in which the environment exerting…

种群与进化 · 定量生物学 2015-06-22 Stefano Bo , Andrea Mazzolini , Antonio Celani

1) Micro-evolutionary predictions are complicated by ecological feedbacks like density dependence, while ecological predictions can be complicated by evolutionary change. A widely used approach in micro-evolution, quantitative genetics,…

种群与进化 · 定量生物学 2015-09-07 Tim Coulson , Floriane Plard , Susanne Schindler , Arpat Ozgul , Jean-Michel Gaillard

While machine learning is rapidly being developed and deployed in health settings such as influenza prediction, there are critical challenges in using data from one environment in another due to variability in features; even within disease…

机器学习 · 统计学 2020-03-10 Vishwali Mhasawade , Nabeel Abdur Rehman , Rumi Chunara