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Motivated by analogies between the spreading of human-to-human infections and of chemical processes, we develop a comprehensive model that accounts both for infection and for transport. In this analogy, the three different populations of…

种群与进化 · 定量生物学 2020-12-08 Harisankar Ramaswamy , Assad A Oberai , Yannis C Yortsos

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

种群与进化 · 定量生物学 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

种群与进化 · 定量生物学 2023-05-31 Sei Zhen Khong , Lanlan Su

At the onset of the Covid-19 pandemic, a number of non-pharmaceutical interventions have been implemented in order to reduce transmission, thus leading to multiple phases of transmission. The disease reproduction number $R_t$, a way of…

应用统计 · 统计学 2023-05-03 Petros Barmpounakis , Nikolaos Demiris

In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with…

物理与社会 · 物理学 2017-08-23 Junbo Jia , Zhen Jin , Xinchu Fu

The spread of infectious epidemics is often accelerated by super-spreader events. Understanding their effect is important, particularly in the context of standard epidemiological models, which require estimates for parameters such as $R_0$.…

种群与进化 · 定量生物学 2021-03-29 Harisankar Ramaswamy , Assad A Oberai , Mitul Luhar , Yannis C Yortsos

An epidemic Susceptible-Vaccinated-Infected-Removed-Susceptible (SVIRS) model is presented on a weighted-undirected network with graph Laplacian diffusion. Disease-free equilibrium always exists while the existence and uniqueness of endemic…

数值分析 · 数学 2025-03-25 Madhab Barman , Nachiketa Mishra

Our paper presents three new classes of models: SIR-PH, SIR-PH-FA, and SIR-PH-IA, and states two problems we would like to solve about them. Recall that deterministic mathematical epidemiology has one basic general law, the R0 alternative"…

种群与进化 · 定量生物学 2022-05-10 Florin Avram , Rim Adenane , Andrei Halanay

Reproduction numbers are widely used for the estimation and prediction of epidemic spreading processes over networks. However, reproduction numbers do not enable estimation and prediction in individual communities within networks, and they…

系统与控制 · 电气工程与系统科学 2025-06-23 Baike She , Philip E. Paré , Matthew Hale

Transmission dynamics of infectious diseases are often studied using compartmental mathematical models, which are commonly represented as systems of autonomous ordinary differential equations. A key step in the analysis of such models is to…

种群与进化 · 定量生物学 2025-12-15 David J. D. Earn , C. Connell McCluskey

We discuss how the presence of a large set of asymptomatic infectives changes our estimate of the COVID-19 basic reproduction number, also known as $R_0$.

种群与进化 · 定量生物学 2020-04-14 Giuseppe Gaeta

We show we can control an epidemic reaction-diffusion on a directed, and heterogeneous, network by redirecting the flows, thanks to the optimisation of well-designed loss functions, in particular the basic reproduction number of the model.…

动力系统 · 数学 2022-02-07 Pierre-Yves Massé , Quentin Laborde , Maria Cherifa , Jules Olayé , Laurent Oudre

We extend a recent investigation by Meehan et al. (2019) regarding the global stability properties of the general Kermack-McKendrick (renewal) model to the multi-strain case. We demonstrate that the basic reproduction number of each strain…

种群与进化 · 定量生物学 2019-07-03 Michael T. Meehan , Daniel G. Cocks , Emma S. McBryde

Ordinary differential equation (ODE) models used in mathematical epidemiology assume explicitly or implicitly large populations. For the study of infections in a hospital this is an extremely restrictive assumption as typically a hospital…

An epidemic model, where the dispersal is approximated by nonlocal diffusion operator and spatial domain has one ?xed boundary and one free boundary, is considered in this paper. Firstly, using some elementary analysis instead of…

偏微分方程分析 · 数学 2024-05-08 Lei Li , Mingxin Wang

The reproductive number R_0 (and its value after initial disease emergence R) has long been used to predict the likelihood of pathogen invasion, to gauge the potential severity of an epidemic, and to set policy around interventions.…

种群与进化 · 定量生物学 2020-06-29 Clara L. Shaw , David A. Kennedy

One clear aspect of behaviour in the COVID-19 pandemic has been people's focus on, and response to, reported or observed infection numbers in their community. We describe a simple model of infectious disease spread in a pandemic situation…

种群与进化 · 定量生物学 2022-02-24 Fintan Costello , Paul Watts , Rita Howe

In this paper, we first propose a diffusive pathogen infection model with general incidence rate which incorporates cell-to-cell transmission. By applying the theory of monotone dynamical systems, we prove that the model admits the global…

偏微分方程分析 · 数学 2026-02-24 Shohel Ahmed

Structured epidemic models can be formulated as first-order hyperbolic PDEs, where the "spatial" variables represent individual traits, called structures. For models with two structures, we propose a numerical technique to approximate…

We study a multi-group SAIRS-type epidemic model with vaccination. The role of asymptomatic and symptomatic infectious individuals is explicitly considered in the transmission pattern of the disease among the groups in which the population…

动力系统 · 数学 2023-05-23 Stefania Ottaviano , Mattia Sensi , Sara Sottile