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Cell monolayers provide an interesting example of active matter, exhibiting a phase transition from a flowing to jammed state as they age. Here we report experiments and numerical simulations illustrating how a jammed cellular layer rapidly…
The kinetics of the assembly of semiflexible filaments through end-to-end annealing is key to the structure of the cytoskeleton, but is not understood. We analyze this problem through scaling theory and simulations, and uncover a regime…
Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…
The relaxation of an elastic network, constructed by a contact map of a fractal (crumpled) polymer globule is investigated. We found that: i) the slowest mode of the network is separated from the rest of the spectrum by a wide gap, and ii)…
In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…
Plasmodium of \emph{Physarum polycephalum} is a single huge (visible by naked eye) cell with myriad of nuclei. The plasmodium is a promising substrate for non-classical, nature-inspired, computing devices. It is capable for approximation of…
From mass extinction to cell death, complex networked systems often exhibit abrupt dynamic transitions between desirable and undesirable states. Such transitions are often caused by topological perturbations, such as node or link removal,…
Plasmodium of acellular slime mould Physarum polycephalum exhibits traits of wave-like behaviour. The plasmodium's behaviour can be finely tuned in laboratory experiments by using herbal tablets. A single tablet acts as a fixed attractor:…
Neuronal function requires precise spatial organization of mitochondria to meet localized energetic demand. However, the physical constraints governing mitochondrial transport in axons remain poorly defined. Bidirectional motor-driven…
The phloem vascular system facilitates transport of energy-rich sugar and signaling molecules in plants, thus permitting long range communication within the organism and growth of non-photosynthesizing organs such as roots and fruits. The…
In this article, we propose a general framework to study the dynamics and topology of cellular networks that capture the geometry of cell packings in two-dimensional tissues. Such epithelia undergo large-scale deformation during…
Effective wound repair treatments rely on a clear picture of how cell proliferation and migration are coordinated during tissue restoration. Fibroblasts are key contributors to tissue restoration in the dermis, and modern imaging tools…
Phyllotactic patterns, i.e. regular arrangements of leaves or seeds around a plant stem, are fascinating examples of complex structures encountered in Nature. In botany, their symmetries develop when a new primordium periodically grows in…
The Dynamic Template model of biological cell membranes and the cytoplasm as spatially organised fluid layers is extended to plant cells, and is shown to offer a feasible shear driven mechanism for the co-alignment of internal and external…
Recent advances in microscopy techniques has uncovered unique aspects of flagella-driven motility in bacteria. A remarkable example is the discovery of flagellar wrapping, a phenomenon whereby a bacterium wraps its flagellum (or flagellar…
Intracellular transport is essential for maintaining proper cellular function in most eukaryotic cells, with perturbations in active transport resulting in several types of disease. Efficient delivery of critical cargos to specific…
Bacterial swarming is a rapid mass-migration, in which thousands of cells spread collectively to colonize a surface. Physically, swarming is a natural example of active particles that use energy to generate motion. Accordingly,…
Transitions from quiescence to collective migration in epithelia underlie wound healing and cancer invasion, yet their physical origin remains poorly understood. Here we show that quiescent epithelial monolayers store spatially contractile…
The spatial organization of a passive scalar plume originating from a point source in a turbulent boundary layer is studied to understand its meandering characteristics. We focus shortly downstream of the isokinetic injection ($1.5\le…
The plasmodium of the slime mould Physarum polycephalum has recently received significant attention for its value as a highly malleable amorphous computing substrate. In laboratory-based experiments, micro- and nanoscale artificial circuit…