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Multiple hypothesis testing is a core problem in statistical inference and arises in almost every scientific field. Given a set of null hypotheses $\mathcal{H}(n) = (H_1,\dotsc, H_n)$, Benjamini and Hochberg introduced the false discovery…

统计理论 · 数学 2017-07-10 Adel Javanmard , Andrea Montanari

Multiple hypothesis testing, a situation when we wish to consider many hypotheses, is a core problem in statistical inference that arises in almost every scientific field. In this setting, controlling the false discovery rate (FDR), which…

统计理论 · 数学 2019-03-19 Shiyun Chen , Shiva Kasiviswanathan

Online multiple hypothesis testing has attracted a lot of attention in many applications, e.g., anomaly status detection and stock market price monitoring. The state-of-the-art generalized $\alpha$-investing (GAI) algorithms can control…

统计方法学 · 统计学 2025-08-05 Yifan Zhang , Zijian Wei , Haojie Ren , Changliang Zou

Multiple hypotheses testing is a core problem in statistical inference and arises in almost every scientific field. Given a sequence of null hypotheses $\mathcal{H}(n) = (H_1,..., H_n)$, Benjamini and Hochberg…

统计方法学 · 统计学 2015-03-05 Adel Javanmard , Andrea Montanari

Modern biomedical research frequently involves testing multiple related hypotheses, while maintaining control over a suitable error rate. In many applications the false discovery rate (FDR), which is the expected proportion of false…

统计方法学 · 统计学 2018-09-27 David S. Robertson , James M. S. Wason

In hypothesis testing, a false discovery occurs when a hypothesis is incorrectly rejected due to noise in the sample. When adaptively testing multiple hypotheses, the probability of a false discovery increases as more tests are performed.…

机器学习 · 统计学 2020-10-22 Wanrong Zhang , Gautam Kamath , Rachel Cummings

In many scientific applications, hypotheses are generated and tested continuously in a stream. We develop a framework for improving online multiple testing procedures with false discovery rate (FDR) control under arbitrary dependence. Our…

统计方法学 · 统计学 2026-03-27 Ziyu Xu , Lasse Fischer , Aaditya Ramdas

Online testing procedures assume that hypotheses are observed in sequence, and allow the significance thresholds for upcoming tests to depend on the test statistics observed so far. Some of the most popular online methods include alpha…

统计方法学 · 统计学 2022-02-11 Aaron Fisher

A new online multiple testing procedure is described in the context of anomaly detection, which controls the False Discovery Rate (FDR). An accurate anomaly detector must control the false positive rate at a prescribed level while keeping…

统计方法学 · 统计学 2024-12-17 Etienne Krönert , Alain Célisse , Dalila Hattab

In the online false discovery rate (FDR) problem, one observes a possibly infinite sequence of $p$-values $P_1,P_2,\dots$, each testing a different null hypothesis, and an algorithm must pick a sequence of rejection thresholds…

统计方法学 · 统计学 2019-07-12 Aaditya Ramdas , Tijana Zrnic , Martin Wainwright , Michael Jordan

Modern data analysis frequently involves large-scale hypothesis testing, which naturally gives rise to the problem of maintaining control of a suitable type I error rate, such as the false discovery rate (FDR). In many biomedical and…

统计方法学 · 统计学 2023-07-25 David S. Robertson , James M. S. Wason , Aaditya Ramdas

A scientist tests a continuous stream of hypotheses over time in the course of her investigation -- she does not test a predetermined, fixed number of hypotheses. The scientist wishes to make as many discoveries as possible while ensuring…

统计方法学 · 统计学 2023-11-14 Ziyu Xu , Aaditya Ramdas

Online testing procedures aim to control the extent of false discoveries over a sequence of hypothesis tests, allowing for the possibility that early-stage test results influence the choice of hypotheses to be tested in later stages.…

统计方法学 · 统计学 2021-10-18 Aaron Fisher

The increasing prevalence and utility of large, public databases necessitates the development of appropriate methods for controlling false discovery. Motivated by this challenge, we discuss the generic problem of testing a possibly infinite…

统计方法学 · 统计学 2013-07-03 Ehud Aharoni , Saharon Rosset

One important partition of algorithms for controlling the false discovery rate (FDR) in multiple testing is into offline and online algorithms. The first generally achieve significantly higher power of discovery, while the latter allow…

统计方法学 · 统计学 2021-03-05 Tijana Zrnic , Daniel L. Jiang , Aaditya Ramdas , Michael I. Jordan

The False Discovery Rate (FDR) is a new statistical procedure to control the number of mistakes made when performing multiple hypothesis tests, i.e. when comparing many data against a given model hypothesis. The key advantage of FDR is that…

This paper is a review of the popular Benjamini Hochberg Method and other related useful methods of Multiple Hypothesis testing. This is written with the purpose of serving a short but complete easy to understand review of the main article…

统计方法学 · 统计学 2014-06-30 Anish Acharya

We study online multiple testing with feedback, where decisions are made sequentially and the true state of the hypothesis is revealed after the decision has been made, either instantly or with a delay. We propose GAIF, a feedback-enhanced…

统计方法学 · 统计学 2026-04-14 Lin Lu , Yuyang Huo , Haojie Ren , Zhaojun Wang , Changliang Zou

We consider the problem of asynchronous online testing, aimed at providing control of the false discovery rate (FDR) during a continual stream of data collection and testing, where each test may be a sequential test that can start and stop…

统计方法学 · 统计学 2020-08-25 Tijana Zrnic , Aaditya Ramdas , Michael I. Jordan

When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate (FDR) assume that all p-values are available at the time point of test…

统计方法学 · 统计学 2021-12-21 Sonja Zehetmayer , Martin Posch , Franz Koenig
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