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Biological tissues have been observed to display emergent fluid-like properties, owing to physical interactions between cells. However, it remains unclear in general how these fluid-like properties affect tissue structure and function.…

软凝聚态物质 · 物理学 2026-02-24 Giulia L. Celora , Benjamin J. Walker , Mohit P. Dalwadi , Philip Pearce

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

细胞行为 · 定量生物学 2015-12-09 Gabriele Micali , Robert G. Endres

We introduce mesoscopic and macroscopic model equations of chemotaxis with anomalous subdiffusion for modelling chemically directed transport of biological organisms in changing chemical environments with diffusion hindered by traps or…

动力系统 · 数学 2012-12-03 T. A. M. Langlands , B. I. Henry

Chemotaxis and auto-chemotaxis play an important role in many essential biological processes. We present a self-propelling artificial swimmer system which exhibits chemotaxis as well as negative auto-chemotaxis. Oil droplets in an aqueous…

软凝聚态物质 · 物理学 2019-10-15 Chenyu Jin , Carsten Krüger , Corinna C. Maass

We describe a method for programming the autonomous navigation of active colloidal particles in response to spatial gradients in a scalar stimulus. Functional behaviors such as positive or negative chemotaxis are encoded in the particle…

软凝聚态物质 · 物理学 2019-12-11 Yong Dou , Kyle J. M. Bishop

The present work was inspired by the recent developments in laboratory experiments made on chip, where culturing of multiple cell species was possible. The model is based on coupled reaction-diffusion-transport equations with chemotaxis,…

数值分析 · 数学 2020-07-22 E. C. Braun , G. Bretti , R. Natalini

A simple model is studied for the chemotactic movement of biological cells in the presence of a periodic chemical wave. It incorporates the feature of adaptation that may play an important role in allowing for ``rectified" chemotaxis:…

凝聚态物理 · 物理学 2009-10-28 Raymond E. Goldstein

As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell…

偏微分方程分析 · 数学 2022-11-09 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Manuel Doblaré , Eamonn A. Gaffney

Chemotaxis plays a crucial role in a variety of processes in biology and ecology. Quite often it acts to improve efficiency of biological reactions. One example is the immune system signalling, where infected tissues release chemokines…

偏微分方程分析 · 数学 2020-04-15 Alexander Kiselev , Fedor Nazarov , Lenya Ryzhik , Yao Yao

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models to describe the phenomenon are the celebrated Keller-Segel equation and a…

偏微分方程分析 · 数学 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

Chemotaxis and reactions are fundamental processes in biology, often intricately intertwined. Chemotaxis, in particular, can be crucial in maintaining and accelerating a reaction. In this work, we extend the investigation initiated by…

偏微分方程分析 · 数学 2024-12-31 Crystianne L. De Andrade , Alexander A. Kiselev

The creation of synthetic systems that emulate the defining properties of living matter, such as motility, gradient-sensing, signalling and replication, is a grand challenge of biomimetics. Such imitations of life crucially contain active…

软凝聚态物质 · 物理学 2015-06-17 Suropriya Saha , Ramin Golestanian , Sriram Ramaswamy

Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the…

生物物理 · 物理学 2020-07-23 Luis Gómez Nava , Robert Großmann , Marius Hintsche , Carsten Beta , Fernando Peruani

Self-powered motion in catalytic colloidal particles provides a compelling example of active matter, i.e. systems that engage in single-particle and collective behavior far from equilibrium. The long-time, long-distance behavior of such…

软凝聚态物质 · 物理学 2017-10-25 Young-Moo Byun , Paul E. Lammert , Yiying Hong , Ayusman Sen , Vincent H. Crespi

The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

细胞行为 · 定量生物学 2007-05-23 Radek Erban , Hans G. Othmer

A wide array of biological systems can navigate in shallow gradients of chemoattractant with remarkable precision. Whilst previous approaches model such systems using coarse-grained chemical density profiles, we construct a dynamical model…

生物物理 · 物理学 2023-12-19 Jacob Knight , Paula García-Galindo , Johannes Pausch , Gunnar Pruessner

A large variety of microorganisms produce molecules to communicate via complex signaling mechanisms such as quorum sensing and chemotaxis. The biological diversity is enormous, but synthetic inanimate colloidal microswimmers mimic…

软凝聚态物质 · 物理学 2019-10-01 Jens Grauer , Hartmut Löwen , Avraham Be'er , Benno Liebchen

The ability to navigate in complex, inhomogeneous environments is fundamental to survival at all length scales, giving rise to the rapid development of various subfields in bio-locomotion such as the well established concept of chemotaxis.…

软凝聚态物质 · 物理学 2020-05-06 Yuanjian Zheng , Hartmut Löwen

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

生物物理 · 物理学 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Chemotaxis is typically modeled in the context of cellular motion towards a static, exogenous source of chemoattractant. Here, we propose a time-dependent mechanism of chemotaxis in which a self-propelled particle ({\it e.g.}, a cell)…

细胞行为 · 定量生物学 2026-05-12 Sarah A. Nowak , Buddhapriya Chakrabarti , Tom Chou , Ajay Gopinathan