相关论文: Invariant death
The Penna model is a model of evolutionary ageing through mutation accumulation where traditionally time and the age of an organism are treated as discrete variables and an organism's genome by a binary bit string. We reformulate the…
The Gompertz law of dependence of human mortality rate on age is derived from a simple model of death as a result of the exponentially rare escape of abnormal cells from immunological response.
In this paper we derive a statistical law of Life. It governs the probability of death, or complementary of survival, of the living organisms. We have deduced such a law coupling the widely used Weibull statistics, developed for describing…
Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-called scaling laws relating an observable quantity with a…
Mutation-induced drug resistance in cancer often causes the failure of therapies and cancer recurrence, despite an initial tumor reduction. The timing of such cancer recurrence is governed by a balance between several factors such as…
The diversity of cell populations is regulated by extracellular and intracellular variability. The latter includes genetic, epigenetic and stochastic variability, all contributing to the experimentally observed heterogeneity in response to…
In present paper we evaluate the fine structure constant variation, that should take place as the Universe expands and its curvature is changed adiabatically. Such variation of the fine structure constant is attributed to an energy losses…
We show that observational limits on the possible time variation of constants of Nature are significantly affected by allowing for both space and time variation. Bekenstein's generalisation of Maxwell's equations to allow for cosmological…
Infant deaths and old age deaths are very different. The former are mostly due to severe congenital malformations of one or a small number of specific organs. On the contrary, old age deaths are largely the outcome of a long process of…
A generalised form of time-translation-invariance permits to re-derive the known generic phenomenology of ageing, which arises in classical many-body systems after a quench from an initially disordered system to a temperature $T\leq T_c$,…
Correlations between high life expectancy and low lifespan inequality are frequently observed. A recent article seeks to explain this phenomenon by proposing that a mortality improvement maps to life expectancy and relative lifespan…
Standard evolutionary theories of aging and mortality, implicitly based on assumptions of spatial averaging, hold that natural selection cannot favor shorter lifespan without direct compensating benefit to individual reproductive success.…
Various features of the development of individual living species, including individual humans, are programmed. Is death also programmed, and if yes, how is it implemented and what can be the underlying mechanism providing the inevitability…
In the past decade the phenomenology of quantum gravity has been dominated by the search of violations of Lorentz invariance. However, there are very serious arguments that led us to assume that this invariance is a symmetry in Nature. This…
A field of random space-time events exhibiting complete spatial-temporal randomness appears statistically identical to all observers. Boost invariant lengths naturally emerge when we examine fluctuation scales of this field such as the…
Lifespan distributions of populations of quite diverse species such as humans and yeast seem to surprisingly well follow the same empirical Gompertz-Makeham law, which basically predicts an exponential increase of mortality rate with age.…
In some scientific fields, a scaling is able to modify the topology of an observed object. Our goal in the present work is to introduce a new formalism adapted to the mathematical representation of this kind of phenomenon. To this end, we…
Urban scaling theory posits that urban indicators follow power-law relations with population, yet the evolution of these patterns - and the role of regional differences in settings marked by social inequalities and unplanned urbanization -…
It is shown that if the computer model of biological ageing proposed by Stauffer is modified such that the late reproduction is privileged then the Gompertz law of exponential increase of mortality can be retrieved.
Many theories of modified gravity with higher order derivatives are usually ignored because of serious problems that appear due to an additional ghost degree of freedom. Most dangerously, it causes an immediate decay of the vacuum. However,…