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Motivated by an application involving additively manufactured bioresorbable polymer scaffolds supporting bone tissue regeneration, we investigate the impact of uncertain geometry perturbations on the effective mechanical properties of…

偏微分方程分析 · 数学 2023-04-19 Patrick Dondl , Yongming Luo , Stefan Neukamm , Steve Wolff-Vorbeck

In turbulence modeling, we are concerned with finding closure models that represent the effect of the subgrid scales on the resolved scales. Recent approaches gravitate towards machine learning techniques to construct such models. However,…

数值分析 · 数学 2024-03-18 Toby van Gastelen , Wouter Edeling , Benjamin Sanderse

When a neural network can learn multiple distinct algorithms to solve a task, how does it "choose" between them during training? To approach this question, we take inspiration from ecology: when multiple species coexist, they eventually…

机器学习 · 计算机科学 2024-05-28 Xiaoman Delores Ding , Zifan Carl Guo , Eric J. Michaud , Ziming Liu , Max Tegmark

The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

生物物理 · 物理学 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

The spatial preferential attachment (SPA) is a model for complex networks. In the SPA model, nodes are embedded in a metric space, and each node has a sphere of influence whose size increases if the node gains an in-link, and otherwise…

社会与信息网络 · 计算机科学 2015-06-22 Jeannette Janssen , Pawel Pralat , Rory Wilson

The main purpose of this work is the mathematical modelling of large populations of cells under different deterministic interactions among themselves, in balance with naturally random diffusion. We focus on cell-cell adhesion mechanisms for…

偏微分方程分析 · 数学 2025-03-19 Carlo Giambiagi Ferrari , Francisco Guillen-Gonzalez , Mayte Perez-Llanos , Antonio Suarez

The spring network model constitutes the backbone in the representations of a host of physical systems. In this work, we report the disturbance-driven microscopic dynamics of an isolated, closed spring network of spherical topology in…

软凝聚态物质 · 物理学 2025-08-26 Zhenwei Yao

It has been hypothesized that some form of "modular" structure in artificial neural networks should be useful for learning, compositionality, and generalization. However, defining and quantifying modularity remains an open problem. We cast…

机器学习 · 计算机科学 2022-06-23 Richard D. Lange , David S. Rolnick , Konrad P. Kording

The measurement of cellular traction forces on soft elastic substrates has become a standard tool for many labs working on mechanobiology. Here we review the basic principles and different variants of this approach. In general, the…

定量方法 · 定量生物学 2015-06-09 Ulrich S. Schwarz , Jerome R. D. Soine

Fast and accurate structural dynamics analysis is important for structural design and damage assessment. Structural dynamics analysis leveraging machine learning techniques has become a popular research focus in recent years. Although the…

地球物理 · 物理学 2020-12-29 Yuan Feng , Hexiang Wang , Han Yang , Fangbo Wang

Cell biomechanics involve a great number of complex phenomena that are fundamental to the evolution of life itself and other associated processes, ranging from the very early stages of embryo-genesis to the maintenance of damaged structures…

计算机视觉与模式识别 · 计算机科学 2025-09-09 Juan Olalla-Pombo , Alberto Badías , Miguel Ángel Sanz-Gómez , José María Benítez , Francisco Javier Montáns

In this paper we study the optimal reinforcement of an elastic membrane, fixed at its boundary, by means of a network (connected onedimensional structure), that has to be found in a suitable admissible class. We show the existence of an…

偏微分方程分析 · 数学 2019-05-22 Giovanni Alberti , Giuseppe Buttazzo , Serena Guarino Lo Bianco , Edouard Oudet

We provide universal formulae for the limiting stretching and bending energies of triangulated membrane networks endowed with nearest neighbor bond potentials and cosine-type dihedral angle potentials. The given formulae account for finite…

材料科学 · 物理学 2015-05-27 Bernd Schmidt , Fernando Fraternali

We study the effect of the spatial distribution of active force dipoles on the folding pathways and mechanical stability of rigid-elastic networks using Langevin dynamics simulations. While it has been shown in Majumdar et al., J. Chem.…

软凝聚态物质 · 物理学 2026-04-20 Debjyoti Majumdar

The introduction of structural defects in otherwise periodic media is well known to grant exceptional space control and localization of waves in various physical fields, including elasticity. Despite the variety of designs proposed so far,…

应用物理 · 物理学 2021-11-18 Marco Miniaci , Florian Allein , Raj Kumar Pal

The polarisation of cells and tissues is fundamental for tissue morphogenesis during biological development and regeneration. A deeper understanding of biological polarity pattern formation can be gained from the consideration of pattern…

细胞行为 · 定量生物学 2017-10-23 Karl B. Hoffmann , Anja Voss-Böhme , Jochen C. Rink , Lutz Brusch

We explore the range over which the elasticity of disordered spring networks can be manipulated by the removal of selected bonds. By taking into account the local response of a bond, we demonstrate that the effectiveness of pruning can be…

软凝聚态物质 · 物理学 2017-08-25 Daniel Hexner , Andrea J. Liu , Sidney R. Nagel

Normalizing flows (NF) are a class of powerful generative models that have gained popularity in recent years due to their ability to model complex distributions with high flexibility and expressiveness. In this work, we introduce a new type…

机器学习 · 计算机科学 2023-06-08 Jonas Köhler , Michele Invernizzi , Pim de Haan , Frank Noé

This work explores the development and the analysis of an efficient reduced order model for the study of a bifurcating phenomenon, known as the Coand\u{a} effect, in a multi-physics setting involving fluid and solid media. Taking into…

数值分析 · 数学 2022-09-14 Moaad Khamlich , Federico Pichi , Gianluigi Rozza

In this work we present a nonlocal conservation law with a velocity depending on an integral term over a part of the space. The model class covers already existing models in literature, but it is also able to describe new dynamics mainly…

偏微分方程分析 · 数学 2023-04-25 Jan Friedrich , Simone Göttlich , Alexander Keimer , Lukas Pflug