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The classical Luria-Delbr\"uck model for fluctuation analysis is extended to the case where cells can either divide or die at the end of their generation time. This leads to a family of probability distributions generalizing the…

种群与进化 · 定量生物学 2013-05-30 Bernard Ycart

Methods for predicting the probability and timing of a species' extinction are typically based on a combination of theoretical models and empirical data, and focus on single species population dynamics. Of course, species also interact with…

种群与进化 · 定量生物学 2012-06-11 Gian Marco Palamara , Gustav W. Delius , Matthew J. Smith , Owen L. Petchey

Finding the most powerful node in a dynamic random network, the largest set in a partition-valued stochastic process, or the largest family in an evolving population at a given time, can be a very difficult problem. This is particularly the…

概率论 · 数学 2020-09-09 Cécile Mailler , Peter Mörters , Anna Senkevich

Happ and Greven (2018) developed a methodology for principal components analysis of multivariate functional data observed on different dimensional domains. Their approach relies on an estimation of univariate functional principal components…

统计方法学 · 统计学 2025-01-28 Steven Golovkine , Edward Gunning , Andrew J. Simpkin , Norma Bargary

Birth-death processes form a natural class where ideas and results on large deviations can be tested. In this paper, we derive a large deviation principle under the assumption that the rate of a jump down (death) is growing asymptotically…

概率论 · 数学 2023-08-21 N. D. Vvedenskaya , A. V. Logachov , Y. M. Suhov , A. A. Yambartsev

Individuals may differ in their parameter values. This article discusses a three-step method of studying such differences by calculating and then modeling "individual parameter contributions", making the study of heterogeneity in arbitrary…

统计方法学 · 统计学 2013-04-15 Daniel Leonard Oberski

This paper is devoted to the study of the asymptotic behavior of the principal eigenvalue and basic reproduction ratio associated with periodic population models in a patchy environment for small and large dispersal rates. We first deal…

经典分析与常微分方程 · 数学 2021-08-04 Lei Zhang , Xiao-Qiang Zhao

We study the positive principal eigenvalue of a weighted problem associated with the Neumann spectral fractional Laplacian. This analysis is related to the investigation of the survival threshold in population dynamics. Our main result…

偏微分方程分析 · 数学 2018-11-06 Benedetta Pellacci , Gianmaria Verzini

The linear spline growth model (LSGM), which approximates complex patterns using at least two linear segments, is a popular tool for examining nonlinear change patterns. Among such models, the linear-linear piecewise change pattern is the…

统计方法学 · 统计学 2022-05-10 Jin Liu , Robert A. Perera , Le Kang , Robert M. Kirkpatrick , Roy T. Sabo

We give a decomposition of the posterior predictive variance using the law of total variance and conditioning on a finite dimensional discrete random variable. This random variable summarizes various features of modeling that are used to…

统计方法学 · 统计学 2022-09-02 Dean Dustin , Bertrand Clarke

We discuss the solution of eigenvalue problems associated with partial differential equations that can be written in the generalized form $\m{A}x=\lambda\m{B}x$, where the matrices $\m{A}$ and/or $\m{B}$ may depend on a scalar parameter.…

数值分析 · 数学 2020-10-12 Daniele Boffi , Francesca Gardini , Lucia Gastaldi

We consider a real-valued path; it is possible to associate a tree to this path, and we explore the relations between the tree, the properties of $p$-variation of the path, and integration with respect to the path. In particular, the…

概率论 · 数学 2009-01-22 Jean Picard

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

种群与进化 · 定量生物学 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

We introduce a parameter estimation method that utilizes microscopic data, specifically averages and correlations of selected microscopic observables, to determine the parameters of a stochastic differential equation governing…

统计力学 · 物理学 2026-04-21 Carlos Monago , J. A. de la Torre , Pep Español

The aim of this study is to compare the growth speed of different cell populations measured by their Malthus parameter. We focus on both the age-structured and size-structured equations. A first population (of reference) is composed of…

概率论 · 数学 2017-03-02 Adélaïde Olivier

We discuss a general growth curve including several parameters, whose choice leads to a variety of models including the classical cases of Malthusian, Richards, Gompertz, Logistic and some their generalizations. The advantage is to obtain a…

统计力学 · 物理学 2024-02-05 G. Albano , V. Giorno , P. Román-Román , F. Torres-Ruiz

The goal of this article is to study how much the eigenvalues of large Hermitian random matrices deviate from certain deterministic locations -- or in other words, to investigate optimal rigidity estimates for the eigenvalues. We do this in…

概率论 · 数学 2019-06-05 Tom Claeys , Benjamin Fahs , Gaultier Lambert , Christian Webb

Linear rate equations are used to describe the cascading decay of an initial heavy cluster into fragments. This representation is based upon a triangular matrix of transition rates. We expand the state vector of mass multiplicities, which…

核理论 · 物理学 2009-10-28 B. G. Giraud , W-h. Ma , R. Peschanski

We study regression models for the situation where both dependent and independent variables are square-integrable stochastic processes. Questions concerning the definition and existence of the corresponding functional linear regression…

统计理论 · 数学 2011-02-28 Guozhong He , Hans-Georg Müller , Jane-Ling Wang , Wenjing Yang

The focus of a survival study is partly on the distribution of survival times, and partly on the health or quality of life of patients while they live. Health varies over time, and survival is the most basic aspect of health, so the two…

统计方法学 · 统计学 2016-01-20 Walter Dempsey , Peter McCullagh