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Characterization of the differences between biological and random networks can reveal the design principles that enable the robust realization of crucial biological functions including the establishment of different cell types. Previous…

分子网络 · 定量生物学 2020-08-26 Shubham Tripathi , David A. Kessler , Herbert Levine

We consider a model for heterogeneous 'gene regulatory networks' that is a generalization of the model proposed by Chatterjee and Durrett (2011) as an "annealed approximation" of Kauffmann's (1969) random Boolean networks. In this model,…

概率论 · 数学 2013-10-17 Shirshendu Chatterjee

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

种群与进化 · 定量生物学 2016-10-03 Laura Jetten , Leo van Iersel

Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

动力系统 · 数学 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

We will consider multivariate stochastic processes indexed either by vertices or pairs of vertices of a dynamic network. Under a dynamic network we understand a network with a fixed vertex set and an edge set which changes randomly over…

统计理论 · 数学 2024-07-15 Alexander Kreiss

Constraints placed upon the phenotypes of organisms result from their interactions with the environment. Over evolutionary timescales, these constraints feed back onto smaller molecular subnetworks comprising the organism. The evolution of…

分子网络 · 定量生物学 2015-06-10 Cameron Smith , Ximo Pechuan , Raymond S. Puzio , Daniel Biro , Aviv Bergman

A Boolean network (BN) with $n$ components is a discrete dynamical system described by the successive iterations of a function $f:\{0,1\}^n \to \{0,1\}^n$. This model finds applications in biology, where fixed points play a central role.…

组合数学 · 数学 2022-02-10 Florian Bridoux , Amélia Durbec , Kévin Perrot , Adrien Richard

Neurons modeled by the Rulkov map display a variety of dynamic regimes that include tonic spikes and chaotic bursting. Here we study an ensemble of bursting neurons coupled with the Watts-Strogatz small-world topology. We characterize the…

神经元与认知 · 定量生物学 2023-06-13 R. C. Budzinski , S. R. Lopes , C. Masoller

Bayesian networks are a widely-used class of probabilistic graphical models capable of representing symmetric conditional independence between variables of interest using the topology of the underlying graph. For categorical variables, they…

机器学习 · 统计学 2022-10-07 Gherardo Varando , Federico Carli , Manuele Leonelli

We consider two mathematical dynamical models of gene regulatory networks (GRNs) and obtain results on robust synchronization on these dynamical models based on the existing theoretical results in the coupled cell network formalism. We also…

动力系统 · 数学 2021-11-17 Manuela Aguiar , Ana Dias , Haibo Ruan

The generalization properties of an attractive network of non monotonic neurons which infers concepts from samples are studied. The macroscopic dynamics for the overlap between the state of the neurons with the concepts, well as the…

统计力学 · 物理学 2009-10-31 D. R. C. Dominguez

The dynamics group of an asynchronous cellular automaton (ACA) relates properties of its long term dynamics to the structure of Coxeter groups. The key mathematical feature connecting these diverse fields is involutions. Group-theoretic…

离散数学 · 计算机科学 2010-10-12 Matthew Macauley , Henning S. Mortveit

Phylogenetic networks provide a general framework for modeling reticulate evolutionary processes such as hybridization, recombination, and horizontal gene transfer. In this paper, we study the asymptotic counting of binary phylogenetic…

种群与进化 · 定量生物学 2026-05-25 Hao Yu , Louxin Zhang

A random boolean cellular automaton is a network of boolean gates where the inputs, the boolean function, and the initial state of each gate are chosen randomly. In this article, each gate has two inputs. Let $a$ (respectively $c$) be the…

adap-org · 物理学 2008-02-03 James F. Lynch

We introduce Controlled Stochastic Activity Networks (Controlled SANs), a formal extension of classical Stochastic Activity Networks that integrates explicit control actions into a unified semantic framework for modeling distributed…

形式语言与自动机理论 · 计算机科学 2026-02-10 Ali Movaghar

Global dynamics of a non-linear Cellular Automata is, in general irregular, asymmetric and unpredictable as opposed to that of a linear CA, which is highly systematic and tractable. In the past efforts have been made to systematize…

计算复杂性 · 计算机科学 2008-08-13 Sudhakar Sahoo , Pabitra Pal Choudhury , Mithun Chakraborty

Boolean networks have been successfully used in modelling gene regulatory networks. In this paper we propose a reduction method that reduces the complexity of a Boolean network but keeps dynamical properties and topological features and…

定量方法 · 定量生物学 2009-07-06 Alan Veliz-Cuba

Extensive research on graph-based dynamics and control of multi-agent systems has successfully demonstrated control of robotic swarms, where each robot is perceived as an independent agent virtually connected by a network topology. The…

系统与控制 · 电气工程与系统科学 2025-03-05 Jonathan Lane , Nak-seung Patrick Hyun

Boolean networks are one of the most studied discrete models in the context of the study of gene expression. In order to define the dynamics associated to a Boolean network, there are several \emph{update schemes} that range from parallel…

形式语言与自动机理论 · 计算机科学 2019-01-29 Eric Goles , Pedro Montealegre , Martín Ríos Wilson

Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states…

分子网络 · 定量生物学 2018-06-27 M. Ali Al-Radhawi , Domitilla Del Vecchio , Eduardo D. Sontag
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