中文
相关论文

相关论文: A continuous time stochastic model for biological …

200 篇论文

We study the learning of an external signal by a neural network and the time to forget it when this network is submitted to noise. The presentation of an external stimulus to the recurrent network of binary neurons may change the state of…

概率论 · 数学 2020-06-11 Pascal Helson

We exhibit a stochastic discrete time model that has exactly the Eigen model as its deterministic continuous limit. Such model can be divided into two phases: reproduction followed by neutral selection. This result suggests that Eigen model…

种群与进化 · 定量生物学 2011-02-03 Fabio Musso

Networks observed in real world like social networks, collaboration networks etc., exhibit temporal dynamics, i.e. nodes and edges appear and/or disappear over time. In this paper, we propose a generative, latent space based, statistical…

社会与信息网络 · 计算机科学 2018-11-08 Shubham Gupta , Gaurav Sharma , Ambedkar Dukkipati

Time-varying networks are fast emerging in a wide range of scientific and business disciplines. Most existing dynamic network models are limited to a single-subject and discrete-time setting. In this article, we propose a mixed-effect…

统计方法学 · 统计学 2018-06-12 Jingfei Zhang , Will Wei Sun , Lexin Li

We propose generalizations of a number of standard network models, including the classic random graph, the configuration model, and the stochastic block model, to the case of time-varying networks. We assume that the presence and absence of…

社会与信息网络 · 计算机科学 2018-05-02 Xiao Zhang , Cristopher Moore , M. E. J. Newman

A class of multivariate mixed survival models for continuous and discrete time with a complex covariance structure is introduced in a context of quantitative genetic applications. The methods introduced can be used in many applications in…

应用统计 · 统计学 2014-05-06 Rafael Pimentel Maia , Per Madsen , Rodrigo Labouriau

We propose new continuous-time formulations for first-order stochastic optimization algorithms such as mini-batch gradient descent and variance-reduced methods. We exploit these continuous-time models, together with simple Lyapunov analysis…

最优化与控制 · 数学 2020-03-12 Antonio Orvieto , Aurelien Lucchi

We present a numerical approximation technique for the analysis of continuous-time Markov chains that describe networks of biochemical reactions and play an important role in the stochastic modeling of biological systems. Our approach is…

定量方法 · 定量生物学 2010-05-06 Thomas A. Henzinger , Maria Mateescu , Linar Mikeev , Verena Wolf

We consider a continuous-time stochastic model of spiking neurons. In this model, we have a finite or countable number of neurons which are vertices in some graph $G$ where the edges indicate the synaptic connection between them. We focus…

概率论 · 数学 2020-10-27 Morgan André , Léo Planche

We consider a general class of stochastic networks and ask which network nodes need to be controlled, and how, to stabilize and switch between desired metastable (target) states in terms of the first and second statistical moments of the…

适应与自组织系统 · 物理学 2016-07-20 Dmytro Bielievtsov , Josef Ladenbauer , Klaus Obermayer

The paper explores the capability of continuous-time recurrent neural networks to store and recall precisely timed scores of spike trains. We show (by numerical experiments) that this is indeed possible: within some range of parameters, any…

神经与进化计算 · 计算机科学 2025-07-29 Hugo Aguettaz , Hans-Andrea Loeliger

In this paper, we first propose a new extended mixture model of residual lifetime distributions. We show that this model is suitable in modeling residual lifetime in some practical situations. Several closure properties of some well-known…

统计方法学 · 统计学 2014-12-31 M. Kayid , S. Izadkhah

What is aging? Mechanistic answers to this question remain elusive despite decades of research. Here, we propose a mathematical model of cellular aging based on a model gene interaction network. Our network model is made of only non-aging…

分子网络 · 定量生物学 2023-09-12 Hong Qin

The Cox proportional hazards model is a canonical method in survival analysis for prediction of the life expectancy of a patient given clinical or genetic covariates -- it is a linear model in its original form. In recent years, several…

Network models have been popular for modeling and representing complex relationships and dependencies between observed variables. When data comes from a dynamic stochastic process, a single static network model cannot adequately capture…

机器学习 · 统计学 2013-04-03 Mladen Kolar , Eric P. Xing

Controlling complex dynamical systems has been a topic of considerable interest in academic circles in recent decades. While existing works have primarily focused on closed-loop control schemes with infinite-time durations, this paper…

最优化与控制 · 数学 2025-01-08 Xiaoxiao Peng , Shijie Zhou

Variational inference has had great success in scaling approximate Bayesian inference to big data by exploiting mini-batch training. To date, however, this strategy has been most applicable to models of independent data. We propose an…

机器学习 · 统计学 2021-05-19 Tom Ryder , Dennis Prangle , Andrew Golightly , Isaac Matthews

In this paper we introduce a continuous time stochastic neurite branching model closely related to the discrete time stochastic BES-model. The discrete time BES-model is underlying current attempts to simulate cortical development, but is…

神经元与认知 · 定量生物学 2015-03-17 Ronald A. J. van Elburg

Existing studies on the degree correlation of evolving networks typically rely on differential equations and statistical analysis, resulting in only approximate solutions due to inherent randomness. To address this limitation, we propose an…

统计计算 · 统计学 2024-06-13 Yue Xiao , Xiaojun Zhang

A discrete time stochastic model for a multiagent system given in terms of a large collection of interacting Markov chains is studied. The evolution of the interacting particles is described through a time inhomogeneous transition…

概率论 · 数学 2011-06-17 Amarjit Budhiraja , Pierre Del Moral , Sylvain Rubenthaler