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Emulate the gating mechanism of ionic channels in neurons, we present a mathematical model for the time constant of dynamical systems. Our model is an analytical continues function. The analyses give evidence that one can adjust the…

细胞行为 · 定量生物学 2016-03-29 S. H. Sabzpoushana , A. Ghajarjazyb , M. Nadjafikhahc

This work theoretically studies stochastic neural networks, a main type of neural network in use. We prove that as the width of an optimized stochastic neural network tends to infinity, its predictive variance on the training set decreases…

机器学习 · 计算机科学 2022-05-25 Liu Ziyin , Hanlin Zhang , Xiangming Meng , Yuting Lu , Eric Xing , Masahito Ueda

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

分子网络 · 定量生物学 2025-12-03 Thomas P. Steele , David J. Warne

We consider models of the population or opinion dynamics which result in the non-linear stochastic differential equations (SDEs) exhibiting the spurious long-range memory. In this context, the correspondence between the description of the…

物理与社会 · 物理学 2019-10-28 Vygintas Gontis , Aleksejus Kononovicius

Stochastic reaction networks, which are usually modeled as continuous-time Markov chains on $\mathbb Z^d_{\ge 0}$, and simulated via a version of the "Gillespie algorithm," have proven to be a useful tool for the understanding of processes,…

概率论 · 数学 2025-07-15 David F. Anderson , Aidan S. Howells

We introduce a new class of time-continuous recurrent neural network models. Instead of declaring a learning system's dynamics by implicit nonlinearities, we construct networks of linear first-order dynamical systems modulated via nonlinear…

机器学习 · 计算机科学 2020-12-16 Ramin Hasani , Mathias Lechner , Alexander Amini , Daniela Rus , Radu Grosu

Mathematical models of biological neural networks are associated to a rich and complex class of stochastic processes. In this paper, we consider a simple {\em plastic} neural network whose {\em connectivity/synaptic strength} $(W(t))$…

概率论 · 数学 2021-06-30 Philippe Robert , Gaetan Vignoud

In this work we propose a new class of long-memory models with time-varying fractional parameter. In particular, the dynamics of the long-memory coefficient, $d$, is specified through a stochastic recurrence equation driven by the score of…

统计方法学 · 统计学 2018-12-19 Luisa Bisaglia , Matteo Grigoletto

Latent position models are widely used for the analysis of networks in a variety of research fields. In fact, these models possess a number of desirable theoretical properties, and are particularly easy to interpret. However, statistical…

统计计算 · 统计学 2023-03-08 Riccardo Rastelli , Florian Maire , Nial Friel

Based on the theory of stochastic chemical kinetics, the inherent randomness and stochasticity of biochemical reaction networks can be accurately described by discrete-state continuous-time Markov chains. The analysis of such processes is,…

数值分析 · 数学 2014-10-14 Andreychenko Alexander , Mikeev Linar , Wolf Verena

Biological systems represent time from microseconds to years. An important gap in our knowledge concerns the mechanisms for encoding time intervals of hundreds of milliseconds to minutes that matter for tasks like navigation, communication,…

神经元与认知 · 定量生物学 2025-05-22 Raphaël Lafond-Mercier , Leonard Maler , Avner Wallach , André Longtin

This paper studies an input-driven one-state differential equation model initially developed for an experimentally demonstrated dynamic molecular switch that switches like synapses in the brain do. The linear-in-the-state and…

机器学习 · 计算机科学 2025-08-22 H. I. Nurdin , C. A. Nijhuis

Thought to be responsible for memory, synaptic plasticity has been widely studied in the past few decades. One example of plasticity models is the popular Spike Timing Dependent Plasticity (STDP). The huge litterature of STDP models are…

概率论 · 数学 2018-03-02 Pascal Helson

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

概率论 · 数学 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

Time series forecasting based on deep architectures has been gaining popularity in recent years due to their ability to model complex non-linear temporal dynamics. The recurrent neural network is one such model capable of handling…

机器学习 · 计算机科学 2021-06-28 Zexuan Yin , Paolo Barucca

How can we efficiently propagate uncertainty in a latent state representation with recurrent neural networks? This paper introduces stochastic recurrent neural networks which glue a deterministic recurrent neural network and a state space…

机器学习 · 统计学 2016-11-15 Marco Fraccaro , Søren Kaae Sønderby , Ulrich Paquet , Ole Winther

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

神经元与认知 · 定量生物学 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

The study of temporal networks in discrete time has yielded numerous insights into time-dependent networked systems in a wide variety of applications. For many complex systems, however, it is useful to develop continuous-time models of…

社会与信息网络 · 计算机科学 2021-02-10 Xinzhe Zuo , Mason A Porter

This paper introduces a new neural network model that aims to mimic the biological brain more closely by structuring the network as a complete directed graph that processes continuous data for each timestep. Current neural networks have…

神经与进化计算 · 计算机科学 2024-01-10 Frank Li

Stochastic processes defined on integer valued state spaces are popular within the physical and biological sciences. These models are necessary for capturing the dynamics of small systems where the individual nature of the populations…

机器学习 · 统计学 2024-04-15 Luke O'Loughlin , John Maclean , Andrew Black