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We consider a model for the dynamics of active cells interacting with their quiescent counterparts under the influence of acidity characterized by proton concentration. The active cells perform nonlinear diffusion and infer proliferation or…

偏微分方程分析 · 数学 2025-11-04 Maria Eckardt , Christina Surulescu

Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is…

This work studies distributed (probability) density estimation of large-scale systems. Such problems are motivated by many density-based distributed control tasks in which the real-time density of the swarm is used as feedback information,…

系统与控制 · 电气工程与系统科学 2021-06-03 Tongjia Zheng , Hai Lin

We investigate the asymptotic properties of deep Residual networks (ResNets) as the number of layers increases. We first show the existence of scaling regimes for trained weights markedly different from those implicitly assumed in the…

机器学习 · 计算机科学 2023-01-26 Rama Cont , Alain Rossier , Renyuan Xu

Simulation code for conventional supercomputers serves as a reference for neuromorphic computing systems. The present bottleneck of distributed large-scale spiking neuronal network simulations is the communication between compute nodes.…

分布式、并行与集群计算 · 计算机科学 2026-02-27 Melissa Lober , Markus Diesmann , Susanne Kunkel

Accurate models of robot dynamics are critical for safe and stable control and generalization to novel operational conditions. Hand-designed models, however, may be insufficiently accurate, even after careful parameter tuning. This…

机器人学 · 计算机科学 2021-11-29 Thai Duong , Nikolay Atanasov

We propose a new approach to learning the subgrid-scale model when simulating partial differential equations (PDEs) solved by the method of lines and their representation in chaotic ordinary differential equations, based on neural ordinary…

数值分析 · 数学 2023-04-14 Shinhoo Kang , Emil M. Constantinescu

Neurons process sensory stimuli efficiently, showing sparse yet highly variable ensemble spiking activity involving structured higher-order interactions. Notably, while neural populations are mostly silent, they occasionally exhibit highly…

神经元与认知 · 定量生物学 2025-07-17 Ulises Rodríguez-Domínguez , Hideaki Shimazaki

Discovering a suitable neural network architecture for modeling complex dynamical systems poses a formidable challenge, often involving extensive trial and error and navigation through a high-dimensional hyper-parameter space. In this…

机器学习 · 计算机科学 2024-03-26 Chinmay Datar , Adwait Datar , Felix Dietrich , Wil Schilders

Modeling biological dynamical systems is challenging due to the interdependence of different system components, some of which are not fully understood. To fill existing gaps in our ability to mechanistically model physiological systems, we…

Both discrete and continuum models have been widely used to study rapid granular flow, discrete model is accurate but computationally expensive, whereas continuum model is computationally efficient but its accuracy is doubtful in many…

流体动力学 · 物理学 2015-12-24 Xizhong Chen , Junwu Wang , Jinghai Li

Complex biological processes involve collective behavior of entities (bacteria, cells, animals) over many length and time scales and can be described by discrete models that track individuals or by continuum models involving densities and…

软凝聚态物质 · 物理学 2023-11-16 F. Terragni , W. D. Martinson , M. Carretero , P. K. Maini , L. L. Bonilla

Accurate crowd simulation is crucial for public safety management, emergency evacuation planning, and intelligent transportation systems. However, existing methods, which typically model crowds as a collection of independent individual…

机器学习 · 计算机科学 2026-04-14 Zijin Liu , Xu Geng , Wenshuai Xu , Xiang Zhao , Yan Xia , You Song

Traditionally, calcium dynamics in neurons are modeled using partial differential equations (PDEs) and ordinary differential equations (ODEs). The PDE component focuses on reaction-diffusion processes, while the ODE component addresses…

数值分析 · 数学 2024-07-23 Abel Gurung , Qingguang Guan

Purpose: To develop a neural ordinary differential equation (ODE) model for visualizing deep neural network (DNN) behavior during multi-parametric MRI (mp-MRI) based glioma segmentation as a method to enhance deep learning explainability.…

定量方法 · 定量生物学 2022-03-25 Zhenyu Yang , Zongsheng Hu , Hangjie Ji , Kyle Lafata , Scott Floyd , Fang-Fang Yin , Chunhao Wang

The problem of synchronization in networks of neural mass model populations with discrete couplings is considered. The considered network is hybrid one, therefore Mikheev approach is applied to transform it to the network with time-varying…

适应与自组织系统 · 物理学 2023-05-04 Sergei Plotnikov

The brain produces rhythms in a variety of frequency bands. Some are likely by-products of neuronal processes; others are thought to be top-down. Produced entirely naturally, these rhythms have clearly recognizable beats, but they are very…

动力系统 · 数学 2020-06-09 Benjamin Ambrosio , Lai-Sang Young

We present an account of neuroplasticity with respect to cell-internal processing pathways in relation to membrane and synaptic plasticity. We think traditional synapse-centric, weight-based models of memorization are not sufficient or…

神经元与认知 · 定量生物学 2026-04-27 Gabriele Scheler

A significant challenge in many fields of science and engineering is making sense of time-dependent measurement data by recovering governing equations in the form of differential equations. We focus on finding parsimonious ordinary…

机器学习 · 计算机科学 2024-10-04 Doris Voina , Steven Brunton , J. Nathan Kutz

Multiscale dynamical systems characterized by interacting fast and slow processes are ubiquitous across scientific domains, from climate dynamics to fluid mechanics. Accurate modeling of such systems requires capturing both the long-term…

混沌动力学 · 物理学 2025-11-07 Giulio Del Felice , Ludovico Theo Giorgini