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Miniature DNA sequencing hardware has begun to succeed in mobile contexts, driving demand for efficient machine learning at the edge. This domain leverages deep learning techniques familiar from speech and time-series analysis for both…

硬件体系结构 · 计算机科学 2025-10-13 Sebastian Magierowski , Zhongpan Wu , Abel Beyene , Karim Hammad

We investigate the process of biopolymer translocation through a narrow pore using a multiscale approach which explicitly accounts for the hydrodynamic interactions of the molecule with the surrounding solvent. The simulations confirm that…

生物物理 · 物理学 2009-01-16 Maria Fyta , Simone Melchionna , Sauro Succi , Efthimios Kaxiras

I propose a technique for reading the base sequence of a single DNA molecule using a graphene nanogap.

生物物理 · 物理学 2008-10-20 Henk W. Ch. Postma

Single molecule force spectroscopy of DNA strands adsorbed at surfaces is a powerful technique used in air or liquid environments to quantify their mechanical properties. Although the force responses are limited to unfolding events so far,…

The atomically-precise controlled synthesis of graphene stripes embedded in hexagonal boron nitride opens up new possibilities for the construction of nanodevices with applications in sensing. Here, we explore properties related to…

Confinement strongly influences electrochemical systems, where structural control has enabled advances in nanofluidics, sensing, and energy storage. In electric double-layer capacitors (EDLCs), or supercapacitors, energy density is governed…

化学物理 · 物理学 2026-01-30 Bryce Rives , Filipe Henrique , Pawel Zuk , Ankur Gupta

This paper introduces the use of cable dynamics models as a means to explore the mechanics of DNA on long-length scales. It is on these length scales that DNA forms twisted and curved three-dimensional shapes known as supercoils and loops.…

生物物理 · 物理学 2007-05-23 Sachin Goyal , Todd Lillian , Noel C. Perkins , Edgar Meyhofer

Using first-principles quantum transport simulations, based on the nonequilibrium Green function formalism combined with density functional theory (NEGF+DFT), we examine changes in the total and local electronic currents within the plane of…

介观与纳米尺度物理 · 物理学 2014-11-12 Po-Hao Chang , Haiying Liu , Branislav K. Nikolic

The near-field Coulomb interaction between a nano-emitter and a graphene monolayer results in strong F\"orster-type resonant energy transfer and subsequent fluorescence quenching. Here, we investigate the distance dependence of the energy…

To simulate long time and length scale processes involving DNA it is necessary to use a coarse-grained description. Here we provide an overview of different approaches to such coarse graining, focussing on those at the nucleotide level that…

In the present study the stress transfer mechanism in graphene-polymer systems under tension is examined experimentally using the technique of laser Raman microscopy. We discuss in detail the effect of graphene edge geometry, lateral size…

应用物理 · 物理学 2019-12-11 Ch. Androulidakis , D. Sourlantzis , E. N. Koukaras , A. C. Manikas , C. Galiotis

With the ability to selectively control ionic flux, biological protein ion channels perform a fundamental role in many physiological processes. For practical applications that require the functionality of a biological ion channel, graphene…

Being capable of characterizing DNA local bending is essential to understand thoroughly many biological processes because they involve a local bending of the double helix axis, either intrinsic to the sequence or induced by the binding of…

Theoretical results for the extension of a polymer confined to a channel are usually derived in the limit of infinite contour length. But experimental studies and simulations of DNA molecules confined to nanochannels are not necessarily in…

软凝聚态物质 · 物理学 2015-12-23 T. St Clere Smithe , V. Iarko , A. Muralidhar , E. Werner , K. D. Dorfman , B. Mehlig

This article is a continuation of our previous studies of the frictional anisotropy of metal nanoparticles on the surface of a graphene substrate for other temperature conditions. The friction force acting on palladium nanoparticles on a…

介观与纳米尺度物理 · 物理学 2021-03-30 A. V. Khomenko , M. V. Zakharov

The recently found material graphene is a truly two-dimensional crystal and exhibits, in addition, an extreme mechanical strength. This in combination with the high electron mobility favours graphene for electromechanical investigations…

介观与纳米尺度物理 · 物理学 2012-03-20 T. Mashoff , M. Pratzer , V. Geringer , T. J. Echtermeyer , M. C. Lemme , M. Liebmann , M. Morgenstern

Recently solid state nanopores nanogaps have generated a lot of interest in ultrafast DNA sequencing. However, there are challenges to slow down the DNA translocation process to achieve a single nucleobase resolution. A series of…

应用物理 · 物理学 2020-04-24 Rameshwar L. Kumawat , Priyanka Garg , Gargee Bhattacharyya , Biswarup Pathak

Structural distortions in nano-materials can induce dramatic changes in their electronic properties. This situation is well manifested in graphene, a two-dimensional honeycomb structure of carbon atoms with only one atomic layer thickness.…

介观与纳米尺度物理 · 物理学 2016-08-17 N. -C. Yeh , C. -C. Hsu , M. L. Teague , J. -Q. Wang , D. A. Boyd , C. -C. Chen

We study DNA self-assembly and DNA computation using a coarse-grained DNA model within the directional dynamic bonding framework {[}C. Svaneborg, Comp. Phys. Comm. 183, 1793 (2012){]}. In our model, a single nucleotide or domain is…

软凝聚态物质 · 物理学 2012-06-13 Carsten Svaneborg , Harold Fellermann , Steen Rasmussen

We have measured the mechanical properties of few-layer graphene and graphite flakes that are suspended over circular holes. The spatial profile of the flake's spring constant is measured with an atomic force microscope. The bending…

介观与纳米尺度物理 · 物理学 2012-03-16 Menno Poot , Herre S. J. van der Zant