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This paper aims at a comprehensive understanding on the novel elastic property of double-stranded DNA (dsDNA) discovered very recently through single-molecule manipulation techniques. A general elastic model for double-stranded biopolymers…

软凝聚态物质 · 物理学 2009-10-31 Haijun Zhou , Yang Zhang , Zhong-can Ou-Yang

In recent years there have been a number of proposals to utilize the specificity of DNA based interactions for potential applications in nanoscience. One interesting direction is the self-assembly of micro- and nanoparticle clusters using…

软凝聚态物质 · 物理学 2009-11-13 Nicholas A. Licata , Alexei V. Tkachenko

The combination of self-assembly and electronic properties as well as its true nanoscale dimensions make DNA a promising candidate for a building block of single molecule electronics. We argue that the intrinsic double helix conformation of…

材料科学 · 物理学 2007-05-23 A. V. Malyshev

The unique atomic monolayer structure of graphene gives rise to a broad range of remarkable mechanical folding properties. However, significant challenges remain in effectively harnessing them in a controllable and scalable manner. In this…

Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with…

软凝聚态物质 · 物理学 2012-03-14 Mattaparthi Venkata Satish Kumar , Prabal K Maiti

Single T4-DNA molecules were confined in rectangular-shaped channels with a depth of 300 nm and a width in the range 150-300 nm casted in a poly(dimethylsiloxane) nanofluidic chip. The extensions of the DNA molecules were measured with…

生物物理 · 物理学 2009-11-13 Ce Zhang , Fang Zhang , Jeroen A. van Kan , Johan R. C. van der Maarel

We observed reptation of single DNA molecules in fused silica nanoslits of sub-30 nm height. The reptation behavior and the effect of confinement are quantitatively characterized using orientation correlation and transverse fluctuation…

生物物理 · 物理学 2015-02-19 Jia-Wei Yeh , K. K. Sriram , Alessandro Taloni , Yeng-Long Chen , Chia-Fu Chou

Friction-induced energy dissipation impedes the performance of nanoscale devices during their relative motion. Nevertheless, an ingeniously designed structure which utilizes graphene topping can tune the friction force signal by inducing…

A comprehensive study has been undertaken on the dimensional swelling of graphene-reinforced elastomers in liquids. Anisotropic swelling was observed for samples reinforced with graphene nanoplatelets (GNPs), induced by the in-plane…

应用物理 · 物理学 2020-03-25 Mufeng Liu , Suhao Li , Ian A. Kinloch , Robert J. Young , Dimitrios G. Papageorgiou

Recent advances in operating and manipulating DNA have provided unique experimental possibilities in many fields of DNA research, especially in gene therapy. Researchers have deployed many techniques, experimental and theoretical, to study…

软凝聚态物质 · 物理学 2023-01-04 Arghya Maity , Neha Mathur , Petra Imhof , Navin Singh

We employ a multiscale approach to model the translocation of biopolymers through nanometer size pores. Our computational scheme combines microscopic Langevin molecular dynamics (MD) with a mesoscopic lattice Boltzmann (LB) method for the…

生物物理 · 物理学 2011-11-10 Maria Fyta , Simone Melchionna , Efthimios Kaxiras , Sauro Succi

The distance-geometric graph representation adopts a unified scheme (distance) for representing the geometry of three-dimensional(3D) graphs. It is invariant to rotation and translation of the graph and it reflects pair-wise node…

计算机视觉与模式识别 · 计算机科学 2021-03-23 Daniel T. Chang

The correlations between the sequence of monomers in a polymer and its three-dimensional structure is a grand challenge in polymer science and biology. The properties and functions of macromolecules depend on their 3D shape that has…

材料科学 · 物理学 2021-07-15 Ashwin A Bale , Tarak K Patra

A coarse grained model for flexible polymers end-grafted to repulsive spherical nanoparticles is studied for various chain lengths and grafting densities under good solvent conditions, by Molecular Dynamics methods and density functional…

软凝聚态物质 · 物理学 2015-05-18 Federica Lo Verso , Sergei A. Egorov , Andrey Milchev , Kurt Binder

The last decade, nanopores have emerged as a new and interesting tool for the study of biological macromolecules like proteins and DNA. While biological pores, especially alpha-hemolysin, have been promising for the detection of DNA, their…

生物物理 · 物理学 2015-03-13 Ronald Kox , Stella Deheryan , Chang Chen , Nima Arjmandi , Liesbet Lagae , Gustaaf Borghs

Mixtures of nanoparticles and polymer-like objects are encountered in many nanotechnological applications and biological systems. We study the behavior of grafted polymer layers decorated by nanoparticles that are attracted to the polymers…

软凝聚态物质 · 物理学 2011-10-31 Michael G. Opferman , Rob D. Coalson , David Jasnow , Anton Zilman

It has recently been proposed that the miscibility of nanoparticles with a polymer matrix can be controlled by grafting polymer chains to the nanoparticle surface. As a first step to study this situation, we have used molecular dynamics…

软凝聚态物质 · 物理学 2010-08-06 Joshua Kalb , Douglas Dukes , Sanat K. Kumar , Robert S. Hoy , Gary S. Grest

We have developed a method for depositing graphene monolayers and bilayers with minimum lateral dimensions of 2-10 nm by the mechanical exfoliation of graphite onto the Si(100)-2x1:H surface. Room temperature, ultra-high vacuum (UHV)…

材料科学 · 物理学 2009-11-13 Kyle A. Ritter , Joseph W. Lyding

Flow-driven rotary motors drive functional processes in human society such as windmills and water wheels. Although examples of such rotary motors also feature prominently in cell biology, their synthetic construction at the nanoscale has…

Methods for reducing and directly controlling the speed of DNA through a nanopore are needed to enhance sensing performance for direct strand sequencing and detection/mapping of sequence-specific features. We have created a method for…

生物物理 · 物理学 2018-11-28 Xu Liu , Yuning Zhang , Roland Nagel , Walter Reisner , William B. Dunbar