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Purpose: To derive a clinically-practical margin formula between clinical target volume (CTV) and planning target volume (PTV) for single-fraction stereotactic radiosurgery (SRS).Methods: In previous publications on the margin between the…

医学物理 · 物理学 2012-07-16 Qinghui Zhang , Maria Chan , Yulin Song , Chandra Burman

Purpose: In this modelling study we pursued two main goals. The first was to establish a new CTV-to-PTV expansion which considers the closest and most critical organ at risk (OAR). The second goal was to investigate the impact of the…

医学物理 · 物理学 2023-03-21 Stephan Radonic , Jürgen Besserer , Carla Rohrer Bley , Uwe Schneider , Valeria Meier

Delineating and planning with respect to regions suspected to contain microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently proposed \textit{clinical target distribution} (CTD) is an alternative to the…

医学物理 · 物理学 2023-04-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

Purpose: 3D rotational setup errors in radiotherapy are often ignored by most clinics due to inability to correct or simulate them accurately and efficiently. There are two types of rotation-related problems in a clinical setting. One is to…

医学物理 · 物理学 2013-10-29 Qinghui Zhang , Yulin Song , Maria Chan , Chandra Burman , Yoshiya Yamada

Definition of the clinical target volume (CTV) is one of the weakest links in the radiation therapy chain. In particular, inability to account for uncertainties is a severe limitation in the traditional CTV delineation approach. Here, we…

医学物理 · 物理学 2018-08-15 Nadya Shusharina , David Craft , Yen-Lin Chen , Helen Shih , Thomas Bortfeld

Dose volume histograms are a useful tool in state-of-the-art radiotherapy planning, and it is essential to be aware of their limitations. Dose distributions computed by treatment planning systems are affected by several sources of…

医学物理 · 物理学 2007-06-13 Francisco Cutanda-Henriquez , Silvia Vargas-Castrillon

The Radiotherapy treatment planning optimization process based on a quasi-Newton algorithm with an object function containing dose-volume constraints is not guaranteed to converge when the dose value in the dose-volume constraint is a…

经典分析与常微分方程 · 数学 2008-12-02 I. Hoveijn

A general framework for goal-oriented a posteriori error estimation for finite volume methods is presented. The framework does not rely on recasting finite volume methods as special cases of finite element methods, but instead directly…

数值分析 · 数学 2011-08-24 Qingshan Chen , Max Gunzburger

Floating-point round-off errors are ubiquitous in numerically intensive programs arising in fields such as scientific computing and optimization. As floating-point errors potentially lead to unexpected and catastrophic program failures, one…

计算机科学中的逻辑 · 计算机科学 2026-05-07 Yichen Tao , Hongfei Fu , Jiawei Chen , Jean-Baptiste Jeannin

Partial Volume effects are present at the boundary between any two types of material in a CT image due to the scanner's Point Spread Function, finite voxel resolution, and importantly, the discrepancy in radiodensity between the two…

图像与视频处理 · 电气工程与系统科学 2023-09-06 Aren Beagley , Hannah Richards , Joshua W. Giles

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

机器学习 · 计算机科学 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…

医学物理 · 物理学 2021-09-07 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

In a treatment plan optimization problem for radiotherapy, a clinically acceptable plan is usually generated by an optimization process with weighting factors or reference doses adjusted for organs. Recent discoveries indicate that…

医学物理 · 物理学 2012-10-29 Masoud Zarepisheh , Andres F. Uribe-Sanchez , Nan Li , Xun Jia , Steve B. Jiang

Purpose: The goal of this study was to assess the potential added benefit of accounting for partial volume effects (PVE) in an automatic coronary lumen segmentation algorithm from coronary computed tomography angiography (CCTA). Materials…

图像与视频处理 · 电气工程与系统科学 2019-06-25 Moti Freiman , Hannes Nickisch , Sven Prevrhal , Holger Schmitt , Mani Vembar , Pál Maurovich-Horvat , Patrick Donnelly , Liran Goshen

This work is an attempt to develop an approximate scheme for estimating the volume-based truncation errors in the finite volume analysis of laminar flows. The volume-based truncation error is the net flow error across the faces of a control…

计算物理 · 物理学 2019-04-04 Amir Reza Baserinia

Flat panel computed tomography is used intraoperatively to assess the result of surgery. Due to workflow issues, the acquisition typically cannot be carried out in such a way that the axis aligned multiplanar reconstructions (MPR) of the…

图像与视频处理 · 电气工程与系统科学 2020-07-08 Celia Martín Vicario , Florian Kordon , Felix Denzinger , Markus Weiten , Sarina Thomas , Lisa Kausch , Jochen Franke , Holger Keil , Andreas Maier , Holger Kunze

To compare the dosimetrical differences between plans generated by helical tomotherapy using 2D or 3D margining technique in in prostate cancer. Ten prostate cancer patients were included in this study. For 2D plans, planning target volume…

The causal effects of continuous treatments are often characterized through the average dose response function, which is challenging to estimate from observational data due to confounding and positivity violations. Modified treatment…

统计方法学 · 统计学 2025-01-22 Ziren Jiang , Jared D. Huling

The Single Transferable Vote (STV) is a system of preferential voting employed in multi-seat elections. Each vote cast by a voter is a (potentially partial) ranking over a set of candidates. No techniques currently exist for computing the…

计算机科学与博弈论 · 计算机科学 2017-08-17 Michelle Blom , Peter J. Stuckey , Vanessa J. Teague

In finite volume the partition function of QCD with a given $\theta$ is a sum of different topological sectors with a weight primarily determined by the topological susceptibility. If a physical observable is evaluated only in a fixed…

高能物理 - 格点 · 物理学 2008-11-26 Sinya Aoki , Hidenori Fukaya , Shoji Hashimoto , Tetsuya Onogi
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