相关论文: Presence-absence reasoning for evolutionary phenot…

We propose a model of the speech perception of individual words in the presence of mishearings. This phenomenological approach is based on concepts used in linguistics, and provides a formalism that is universal across languages. We put…

Accurate phenotypic analysis in aquaculture breeding necessitates the quantification of subtle morphological phenotypes. Existing datasets suffer from limitations such as small scale, limited species coverage, and inadequate annotation of…

Any representational enterprise must omit variation in order to function. NASA still uses Newtonian mechanics, though Einstein superseded Newton, and the standard picture of scientific progress cannot explain how. A description that omitted…

With large language models surpassing human performance on an increasing number of benchmarks, we must take a principled approach for targeted evaluation of model capabilities. Inspired by pseudorandomness, we propose pseudointelligence,…

The representation of workflows and processes is essential in materials science engineering, where experimental and computational reproducibility depend on structured and semantically coherent process models. Although numerous ontologies…

Deep learning models have achieved remarkable success in different areas of machine learning over the past decade; however, the size and complexity of these models make them difficult to understand. In an effort to make them more…

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

Persistent homology is a cornerstone of topological data analysis, offering a multiscale summary of topology with robustness to nuisance transformations, such as rotations and small deformations. Persistent homology has seen broad use…

Enthymemes are defined as arguments where a premise or conclusion is left implicit. We tackle the task of generating the implicit premise in an enthymeme, which requires not only an understanding of the stated conclusion and premise but…

Computational phenotyping allows for unsupervised discovery of subgroups of patients as well as corresponding co-occurring medical conditions from electronic health records (EHR). Typically, EHR data contains demographic information,…

There have been a fairly of research interests in exploring the disentanglement of appearance and shape from human images. Most existing endeavours pursuit this goal by either using training images with annotations or regulating the…

Phylogenetic profiles - presence-absence patterns of genes across taxa - are rich information sources for inferring the evolutionary history of genes and gene families. When aggregated across many genes, these profiles can reveal…

Supervised and unsupervised learning using deep neural networks typically aims to exploit the underlying structure in the training data; this structure is often explained using a latent generative process that produces the data, and the…

High-quality data accumulation is now becoming ubiquitous in the health domain. There is increasing opportunity to exploit rich data from normal subjects to improve supervised estimators in specific diseases with notorious data scarcity. We…

The study of neural computation aims to understand the function of a neural system as an information processing machine. Neural systems are undoubtedly complex, necessitating principled and automated tools to abstract away details to…

Rapid advances in genetics, genomics, and imaging have given insight into the molecular and cellular basis of behaviour in a variety of model organisms with unprecedented detail and scope. It is increasingly routine to isolate behavioural…

Large Language Models (LLMs) demonstrate an impressive capacity to recall a vast range of factual knowledge. However, understanding their underlying reasoning and internal mechanisms in exploiting this knowledge remains a key research area.…

Many rare genetic diseases exhibit recognizable facial phenotypes, which are often used as diagnostic clues. However, current facial phenotype diagnostic models, which are trained on image datasets, have high accuracy but often suffer from…

It is proposed that the co-expression of statistically significant motifs among the sequences of a proteome is a phylogenetic trait. From the co-expression matrix of such motifs in a group of prokaryotic proteomes a suitable definition of a…

Concept-based explanations have emerged as a popular way of extracting human-interpretable representations from deep discriminative models. At the same time, the disentanglement learning literature has focused on extracting similar…