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Observability is a modelling property that describes the possibility of inferring the internal state of a system from observations of its output. A related property, structural identifiability, refers to the theoretical possibility of…

定量方法 · 定量生物学 2018-12-12 Alejandro F. Villaverde

We propose a novel shape representation useful for analyzing and processing shape collections, as well for a variety of learning and inference tasks. Unlike most approaches that capture variability in a collection by using a template model…

图形学 · 计算机科学 2018-06-13 Ruqi Huang , Panos Achlioptas , Leonidas Guibas , Maks Ovsjanikov

Connecting the dynamics of biomolecular networks to experimentally measurable cell phenotypes remains a central challenge in systems biology. Here we introduce a model-based definition of phenotype as a partial steady state that is…

分子网络 · 定量生物学 2026-02-18 Samuel Pastva , Kyu Hyong Park , Jordan C. Rozum , Van-Giang Trinh , Réka Albert

Type inference refers to the task of inferring the data type of a given column of data. Current approaches often fail when data contains missing data and anomalies, which are found commonly in real-world data sets. In this paper, we propose…

机器学习 · 计算机科学 2020-03-24 Taha Ceritli , Christopher K. I. Williams , James Geddes

A natural phenomenon occurring in a living system is an outcome of the dynamics of the specific biological network underlying the phenomenon. The collective dynamics have both deterministic and stochastic components. The stochastic nature…

统计力学 · 物理学 2023-09-01 Indrani Bose

Understanding freely moving animal behavior is central to neuroscience, where pose estimation and behavioral understanding form the foundation for linking neural activity to natural actions. Yet both tasks still depend heavily on human…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Jingyang Ke , Weihan Li , Amartya Pradhan , Jeffrey Markowitz , Anqi Wu

Chronic viral infections can persist in an infected person for decades. From the perspective of the virus, a single infection can span thousands of generations, leading to a highly diverse population of viruses with its own complex…

种群与进化 · 定量生物学 2023-05-30 Dmitry Gromov , Ethan O. Romero-Severson

As the public seeks greater accountability and transparency from machine learning algorithms, the research literature on methods to explain algorithms and their outputs has rapidly expanded. Feature importance methods form a popular class…

计算机与社会 · 计算机科学 2021-02-01 Leif Hancox-Li , I. Elizabeth Kumar

Humans and animals are constantly exposed to a continuous stream of sensory information from different modalities. At the same time, they form more compressed representations like concepts or symbols. In species that use language, this…

神经与进化计算 · 计算机科学 2017-06-09 Karla Stepanova , Matej Hoffmann , Zdenek Straka , Frederico B. Klein , Angelo Cangelosi , Michal Vavrecka

In mission-critical domains such as law enforcement and medical diagnosis, the ability to explain and interpret the outputs of deep learning models is crucial for ensuring user trust and supporting informed decision-making. Despite…

计算机视觉与模式识别 · 计算机科学 2024-11-07 Bharat Chandra Yalavarthi , Nalini Ratha

High-throughput data analyses are becoming common in biology, communications, economics and sociology. The vast amounts of data are usually represented in the form of matrices and can be considered as knowledge networks. Spectra-based…

定量方法 · 定量生物学 2010-01-06 Viet-Anh Nguyen , Zdena Koukolikova-Nicola , Franco Bagnoli , Pietro Lio

Mutualistic interactions, where species interact to obtain mutual benefits, constitute an essential component of natural ecosystems. The use of ecological networks to represent the species and their ecological interactions allows the study…

种群与进化 · 定量生物学 2023-11-28 Clàudia Payrató-Borràs , Carlos Gracia-Lázaro , Laura Hernández , Yamir Moreno

An increasing number of dissident voices claim that the standard neo-Darwinian view of genes as 'leaders' and phenotypes as 'followers' during the process of adaptive evolution should be turned on its head. This idea is older than the…

种群与进化 · 定量生物学 2015-03-10 Mauro Santos , Eörs Szathmáry , José F. Fontanari

In empirical studies, the data usually don't include all the variables of interest in an economic model. This paper shows the identification of unobserved variables in observations at the population level. When the observables are distinct…

计量经济学 · 经济学 2022-12-07 Yingyao Hu

Site occupancy models are routinely used to estimate the probability of species presence from either abundance or presence-absence data collected across sites with repeated sampling occasions. In the last two decades, a broad class of…

统计方法学 · 统计学 2022-04-05 Wen-Han Hwang , Jakub Stoklosa , Lu-Fang Chen

Automatic phenotyping is a task of identifying cohorts of patients that match a predefined set of criteria. Phenotyping typically involves classifying long clinical documents that contain thousands of tokens. At the same time, recent…

计算与语言 · 计算机科学 2021-05-17 Xin Su , Timothy Miller , Xiyu Ding , Majid Afshar , Dmitriy Dligach

With the wide adoption of black-box models, instance-based \emph{post hoc} explanation tools, such as LIME and SHAP became increasingly popular. These tools produce explanations, pinpointing contributions of key features associated with a…

人工智能 · 计算机科学 2021-06-30 Timen Stepišnik Perdih , Nada Lavrač , Blaž Škrlj

A finite set is "hidden" if its elements are not directly enumerable or if its size cannot be ascertained via a deterministic query. In public health, epidemiology, demography, ecology and intelligence analysis, researchers have developed a…

统计理论 · 数学 2019-10-17 Si Cheng , Daniel J. Eck , Forrest W. Crawford

The goal of Science is to understand phenomena and systems in order to predict their development and gain control over them. In the scientific process of knowledge elaboration, a crucial role is played by models which, in the language of…

统计力学 · 物理学 2018-10-25 Marco Baldovin , Fabio Cecconi , Massimo Cencini , Andrea Puglisi , Angelo Vulpiani

We consider cross-sectional genetic association studies (common and rare variants) where non-genetic information is available, or feasible to obtain for $N$ individuals, but where it is infeasible to genotype all $N$ individuals. We…

应用统计 · 统计学 2020-02-06 Thea Bjørnland , Anja Bye , Einar Ryeng , Ulrik Wisløff , Mette Langaas
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