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The gradual patterns that model the complex co-variations of attributes of the form "The more/less X, The more/less Y" play a crucial role in many real world applications where the amount of numerical data to manage is important, this is…

机器学习 · 计算机科学 2020-05-25 Michaël Chirmeni Boujike , Jerry Lonlac , Norbert Tsopze , Engelbert Mephu Nguifo

Constructing tests or confidence regions that control over the error rates in the long-run is probably one of the most important problem in statistics. Yet, the theoretical justification for most methods in statistics is asymptotic. The…

统计方法学 · 统计学 2019-01-23 Stéphane Guerrier , Mucyo Karemera , Samuel Orso , Maria-Pia Victoria-Feser

Evidence plays a crucial role in any biomedical research narrative, providing justification for some claims and refutation for others. We seek to build models of scientific argument using information extraction methods from full-text…

计算与语言 · 计算机科学 2025-05-19 Xiangci Li , Gully Burns , Nanyun Peng

The explainability of deep learning models remains a significant challenge, particularly in the medical domain where interpretable outputs are essential for clinical trust and transparency. Path attribution methods such as Integrated…

机器学习 · 计算机科学 2026-05-08 Alexander Geiger , Lars Wagner , Daniel Rueckert , Dirk Wilhelm , Alissa Jell

This work explores hypernetworks: an approach of using a one network, also known as a hypernetwork, to generate the weights for another network. Hypernetworks provide an abstraction that is similar to what is found in nature: the…

机器学习 · 计算机科学 2016-12-02 David Ha , Andrew Dai , Quoc V. Le

Visualisation facilitates the understanding of scientific data both through exploration and explanation of visualised data. Provenance contributes to the understanding of data by containing the contributing factors behind a result. With the…

数据库 · 计算机科学 2015-02-06 Bilal Arshad , Kamran Munir , Richard McClatchey , Saad Liaquat

A common assumption in causal inference from observational data is that there is no hidden confounding. Yet it is, in general, impossible to verify this assumption from a single dataset. Under the assumption of independent causal mechanisms…

统计方法学 · 统计学 2023-11-07 Rickard K. A. Karlsson , Jesse H. Krijthe

We are facing a real challenge when coping with the continuous acceleration of scientific production and the increasingly changing nature of science. In this article, we extend the classical framework of co-word analysis to the study of…

物理与社会 · 物理学 2015-03-13 David Chavalarias , Jean-Philippe Cointet

The phenotype of any organism on earth is, in large part, the consequence of interplay between numerous gene products encoded in the genome, and such interplay between gene products affects the evolutionary fate of the genome itself through…

分子网络 · 定量生物学 2012-01-04 Pan-Jun Kim , Nathan D. Price

Predictive modeling plays key role in providing accurate prognosis and enables us to take a step closer to personalized treatment. We identified two potential sources of human induced biases that can lead to disparate conclusions. We…

应用统计 · 统计学 2017-02-08 Madhuchhanda Bhattacharjee

The use of semantic technologies is gaining significant traction in science communication with a wide array of applications in disciplines including the Life Sciences, Computer Science, and the Social Sciences. Languages like RDF, OWL, and…

数字图书馆 · 计算机科学 2021-11-01 Cristina-Iulia Bucur , Tobias Kuhn , Davide Ceolin , Jacco van Ossenbruggen

Hypothetical induction is recognized as the main reasoning type when scientists make observations about the world and try to propose hypotheses to explain those observations. Past research on hypothetical induction is under a constrained…

计算与语言 · 计算机科学 2024-06-13 Zonglin Yang , Xinya Du , Junxian Li , Jie Zheng , Soujanya Poria , Erik Cambria

The recent explosion of genetic and high dimensional biobank and 'omic' data has provided researchers with the opportunity to investigate the shared genetic origin (pleiotropy) of hundreds to thousands of related phenotypes. However,…

统计方法学 · 统计学 2023-03-21 Weiqiong Huang , Emily C. Hector , Joshua Cape , Chris McKennan

Quantitative population modelling is an invaluable tool for identifying the cascading effects of ecosystem management and interventions. Ecosystem models are often constructed by assuming stability and coexistence in ecological communities…

种群与进化 · 定量生物学 2024-09-06 Sarah A. Vollert , Christopher Drovandi , Matthew P. Adams

Possibility to establish macroscopic phenomenological theory for biological systems, akin to the akin to the well-established framework of thermodynamics, is briefly reviewed. We introduce the concept of an evolutionary fluctuation-response…

生物物理 · 物理学 2024-01-11 Kunihiko Kaneko

Sample overlap is a common issue in evidence synthesis in the field of medical research, particularly when integrating findings from observational studies utilizing existing databases such as registries. Due to the general inaccessibility…

统计方法学 · 统计学 2026-02-26 Zhentian Zhang , Tim Friede , Tim Mathes

Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population consists of cells with various different phenotypes. This…

种群与进化 · 定量生物学 2025-04-01 Rebecca M. Crossley , Philip K. Maini , Ruth E. Baker

This paper presents a framework for automatically learning shape and appearance models for medical (and certain other) images. It is based on the idea that having a more accurate shape and appearance model leads to more accurate image…

计算机视觉与模式识别 · 计算机科学 2019-05-29 John Ashburner , Mikael Brudfors , Kevin Bronik , Yael Balbastre

In the world of science new technology have opened up the possibility to rely on advanced computational methods and models to conduct and produce scientific research. An important aspect of scientific and business workflows is provenance -…

软件工程 · 计算机科学 2025-04-01 Ludwig Stage , Julia Dahlberg , Dimka Karastoyanova

The concept of {\em complexity} (as a quantity) has been plagued by numerous contradictory and confusing definitions. By explicitly recognising a role for the observer of a system, an observer that attaches meaning to data about the system,…

科普物理 · 物理学 2016-09-08 Russell K. Standish