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Understanding computational capabilities of simple biological circuits, such as the regulatory circuits of single-cell organisms, remains an active area of research. Recent theoretical work has shown that a simple regulatory architecture…

生物物理 · 物理学 2022-11-24 Fang Yu , Mikhail Tikhonov

The fluctuation-dissipation relation is calculated for a class of stochastic models obeying a master equation. The transition rates are assumed to obey detailed balance also in the presence of a field. It is shown that in general the linear…

统计力学 · 物理学 2016-08-31 Gregor Diezemann

Delayed interactions are a common property of coupled natural systems and therefore arise in a variety of different applications. For instance, signals in neural or laser networks propagate at finite speed giving rise to delayed…

动力系统 · 数学 2015-06-12 Leonhard Lücken , Jan Philipp Pade , Kolja Knauer , Serhiy Yanchuk

The fluctuations in nonequilibrium systems are under intense theoretical and experimental investigation. Topical ``fluctuation relations'' describe symmetries of the statistical properties of certain observables, in a variety of models and…

统计力学 · 物理学 2011-09-08 Lamberto Rondoni , Carlos Mejia-Monasterio

Understanding and modeling the dynamics of pedestrian crowds can help with designing and increasing the safety of civil facilities. A key feature of crowds is its intrinsic stochasticity, appearing even under very diluted conditions, due to…

物理与社会 · 物理学 2017-03-22 Alessandro Corbetta , Chung-min Lee , Roberto Benzi , Adrian Muntean , Federico Toschi

We show that time-correlation functions of arbitrary order for any random variable in a statistical dynamical system can be calculated as higher-order response functions of the mean history of the variable. The response is to a ``control…

chao-dyn · 物理学 2009-10-31 Gregory L. Eyink

We study the dynamics of networks with coupling delay, from which the connectivity changes over time. The synchronization properties are shown to depend on the interplay of three time scales: the internal time scale of the dynamics, the…

Feedback optimisation is an emerging technique aiming at steering a system to an optimal steady state for a given objective function. We show that it is possible to employ this control strategy in a distributed manner. Moreover, we prove…

最优化与控制 · 数学 2022-03-01 Antonio Terpin , Sylvain Fricker , Michel Perez , Mathias Hudoba de Badyn , Florian Dörfler

In the modern knowledge economy, success demands sustained focus and high cognitive performance. Research suggests that human cognition is linked to a finite resource, and upon its depletion, cognitive functions such as self-control and…

计算机与社会 · 计算机科学 2018-09-11 Nathan O. Hodas , Jacob Hunter , Stephen J. Young , Kristina Lerman

Firing rate fluctuations in neural populations are observed experimentally over multiple time scales, in single neurons, across trials when elicited by stimuli, and across populations. In this work, we examine how firing rate fluctuations…

神经元与认知 · 定量生物学 2026-05-15 Wilten Nicola , Sue Ann Campbell

Biochemical reaction networks are subjected to large fluctuations attributable to small molecule numbers, yet underlie reliable biological functions. Most theoretical approaches describe them as purely deterministic or stochastic dynamical…

分子网络 · 定量生物学 2013-06-11 Jingkui Wang , Marc Lefranc , Quentin Thommen

Dual-process theories play a central role in both psychology and neuroscience, figuring prominently in fields ranging from executive control to reward-based learning to judgment and decision making. In each of these domains, two mechanisms…

神经元与认知 · 定量生物学 2023-10-11 Ted Moskovitz , Kevin Miller , Maneesh Sahani , Matthew M. Botvinick

Although higher-order interactions are known to affect the typical state of dynamical processes giving rise to new collective behavior, how they drive the emergence of rare events and fluctuations is still an open problem. We investigate…

无序系统与神经网络 · 物理学 2024-09-09 Leonardo Di Gaetano , Giorgio Carugno , Federico Battiston , Francesco Coghi

Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

We consider the effects of long-range temporal correlations in many-particle systems, focusing particularly on fluctuations about the typical behaviour. For a specific class of memory dependence we discuss the modification of the large…

统计力学 · 物理学 2015-12-24 Rosemary J. Harris

The temporal activity of many biological systems, including neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. The mechanisms leading to this temporal heterogeneity are yet unknown. Here we show…

无序系统与神经网络 · 物理学 2022-08-03 Merav Stern , Nicolae Istrate , Luca Mazzucato

The time-changing nature of our world demands processing of huge amounts of information in fast and reliable way to generate successful behaviors. Therefore, significant brain resources are devoted to process spatiotemporal information.…

In spatially distributed cellular systems, it is often convenient to represent complicated auxiliary pathways and spatial transport by time-delayed reaction rates. Furthermore, many of the reactants appear in low numbers necessitating a…

定量方法 · 定量生物学 2015-05-14 Matthew Scott

To be effective in sequential data processing, Recurrent Neural Networks (RNNs) are required to keep track of past events by creating memories. While the relation between memories and the network's hidden state dynamics was established over…

机器学习 · 计算机科学 2019-09-17 Doron Haviv , Alexander Rivkind , Omri Barak

Motion forecasting plays a crucial role in autonomous driving, with the aim of predicting the future reasonable motions of traffic agents. Most existing methods mainly model the historical interactions between agents and the environment,…

计算机视觉与模式识别 · 计算机科学 2023-11-09 Miao Kang , Shengqi Wang , Sanping Zhou , Ke Ye , Jingjing Jiang , Nanning Zheng