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We propose and analyse an optimal control problem where the control system is a mathematical model for tuberculosis that considers reinfection. The control functions represent the fraction of early latent and persistent latent individuals…

最优化与控制 · 数学 2014-10-13 Paula Rodrigues , Cristiana J. Silva , Delfim F. M. Torres

Tuberculosis (TB) is a contagious bacterial airborne disease, and is one of the top 10 causes of death worldwide. According to the World Health Organization (WHO), around 1.8 billion people are infected with TB and 1.6 million deaths were…

图像与视频处理 · 电气工程与系统科学 2020-12-29 Chirath Dasanayakaa , Maheshi Buddhinee Dissanayake

We present a model for the silicosis disease mechanism following the original proposal by Tran, Jones, and Donaldson (1995) [9], as modified recently by da Costa, Drmota, and Grinfeld (2020) [4]. The model consists in an infinite ordinary…

经典分析与常微分方程 · 数学 2021-01-29 Fernando P. da Costa , João T. Pinto , Rafael Sasportes

Crohn's disease and intestinal tuberculosis share many overlapping features such as clinical, radiological, endoscopic, and histological features - particularly granulomas, making it challenging to clinically differentiate them. Our…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Shashwat Gupta , Sarthak Gupta , Akshan Agrawal , Mahim Naaz , Rajanikanth Yadav , Priyanka Bagade

Tuberculosis (TB) is among the main public health challenges in Burundi. The literature lacks mathematical models for key parameter estimates of TB transmission dynamics in Burundi. In this paper, the supectible-exposed-infected-recovered…

种群与进化 · 定量生物学 2023-04-05 Steve Sibomanaa , Kelly Joelle Gatore Sinigirira , Paterne Gahungu , David Niyukuri

We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…

最优化与控制 · 数学 2022-01-26 Marcel Fang , Pierre-Alexandre Bliman

Tuberculosis (TB) is a chronic lung disease that occurs due to bacterial infection and is one of the top 10 leading causes of death. Accurate and early detection of TB is very important, otherwise, it could be life-threatening. In this…

Tuberculosis persists as a global health crisis, especially in resource-limited populations and remote regions, with more than 10 million individuals newly infected annually. It stands as a stark symbol of inequity in public health.…

图像与视频处理 · 电气工程与系统科学 2025-03-12 Neel Patel , Alexander Wong , Ashkan Ebadi

Antimicrobial resistance is becoming a major threat to public health throughout the world. Researchers are attempting to contrast it by developing both new antibiotics and patient-specific treatments. In the second case, whole-genome…

应用统计 · 统计学 2023-07-25 Clara Grazian

Automatic classification of active tuberculosis from chest X-ray images has the potential to save lives, especially in low- and mid-income countries where skilled human experts can be scarce. Given the lack of available labeled data to…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Özgür Acar Güler , Manuel Günther , André Anjos

We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions, considering reinfection and post-exposure…

最优化与控制 · 数学 2013-07-15 Cristiana J. Silva , Delfim F. M. Torres

Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, continues to be a major global health threat despite being preventable and curable. This burden is particularly high in low and middle income countries.…

图像与视频处理 · 电气工程与系统科学 2025-01-08 Greeshma K , Vishnukumar S

In this paper we study a nonlinear reaction-diffusion system which models an infectious disease caused by bacteria such as those for cholera. One of the significant features in this model is that a certain portion of the recovered human…

偏微分方程分析 · 数学 2022-02-01 Hong-Ming Yin , Jun Zou

This paper considers the problem of modeling epidemic outbreaks in different regions with a common model, that uses additional information about these regions to adjust its parameters and relieve us of mundanity of data collecting, and…

物理与社会 · 物理学 2024-12-06 Andrei Neverov , Olga Krivorotko

The population model of Busenberg and Travis is a paradigmatic model in ecology and tumour modelling due to its ability to capture interesting phenomena like the segregation of populations. Its singular mathematical structure enforces the…

偏微分方程分析 · 数学 2024-01-29 Gonzalo Galiano , Víctor González-Tabernero

Tuberculosis (TB) is a major global health threat, causing millions of deaths annually. Although early diagnosis and treatment can greatly improve the chances of survival, it remains a major challenge, especially in developing countries.…

计算机视觉与模式识别 · 计算机科学 2023-12-06 Yun Liu , Yu-Huan Wu , Shi-Chen Zhang , Li Liu , Min Wu , Ming-Ming Cheng

Tuberculosis (TB) is an airborne disease caused by the bacterium Mycobacterium tuberculosis (M. tb). Prior to the COVID-19 pandemic, TB was the leading cause of death from an infectious agent globally. However, most people exposed to M. tb…

In epidemiological modelings, the spectral radius of the next generation matrix evaluated at the trivial equilibrium was considered as the basic reproduction number. Also, the global stability of the trivial equilibrium point was determined…

种群与进化 · 定量生物学 2020-06-15 Hyun Mo Yang

We discuss a nonlinear system of partial differential equations modelling the formation of granuloma during tuberculosis infections and prove the global solvability of the homogeneous Neumann problem for \begin{align*} \begin{cases} u_t =…

偏微分方程分析 · 数学 2025-04-11 Mario Fuest , Johannes Lankeit , Masaaki Mizukami

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and primarily affects the lungs, as well as other body parts. TB is spread through the air when an infected person coughs, sneezes, or talks.…

音频与语音处理 · 电气工程与系统科学 2026-03-04 George P. Kafentzis , Stephane Tetsing , Joe Brew , Lola Jover , Mindaugas Galvosas , Carlos Chaccour , Peter M. Small