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For a highly beneficial mutant $A$ entering a randomly reproducing population of constant size, we study the situation when a second beneficial mutant $B$ arises before $A$ has fixed. If the selection coefficient of $B$ is greater than the…

概率论 · 数学 2018-01-08 Sebastian Bossert , Peter Pfaffelhuber

The mean fixation time of a deleterious mutant allele is studied beyond the diffusion approximation. As in Kimura's classical work [M. Kimura, Proc. Natl. Acad. Sci. U.S.A. Vol.77, 522 (1980)], that was motivated by the problem of fixation…

种群与进化 · 定量生物学 2011-02-22 Michael Assaf , Mauro Mobilia

The rate of biological evolution depends on the fixation probability and on the fixation time of new mutants. Intensive research has focused on identifying population structures that augment the fixation probability of advantageous mutants.…

种群与进化 · 定量生物学 2019-03-11 Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

We investigate the statistics of the time taken for a system driven by recruitment to reach fixation. Our model describes a series of experiments where a population is confronted with two identical options, resulting in the system fixating…

统计力学 · 物理学 2015-01-26 Tommaso Biancalani , Louise Dyson , Alan J. McKane

Consider an advantageous allele that arises in a haploid population of size $N$ evolving in continuous time according to a skewed reproduction mechanism, which generates under neutrality genealogies lying in the domain of attraction of a…

概率论 · 数学 2024-09-02 Matthias Birkner , Florin Boenkost , Iulia Dahmer , Cornelia Pokalyuk

We study the evolutionary dynamics of a haploid population of infinite size recombining with a probability $r$ in a two locus model. Starting from a low fitness locus, the population is evolved under mutation, selection and recombination…

种群与进化 · 定量生物学 2010-05-04 Kavita Jain

Computing the rate of evolution in spatially structured populations is difficult. A key quantity is the fixation time of a single mutant with relative reproduction rate $r$ which invades a population of residents. We say that the fixation…

种群与进化 · 定量生物学 2025-09-18 David A. Brewster , Martin A. Nowak , Josef Tkadlec

Stable mixtures of cooperators and defectors are often seen in nature. This fact is at odds with predictions based on linear public goods games under weak selection. That model implies fixation either of cooperators or of defectors, and the…

种群与进化 · 定量生物学 2012-11-15 Roberto H. Schonmann , Renato Vicente , Robert Boyd

We investigate the process of fixation of advantageous mutations in an asexual population. We assume that the effect of each beneficial mutation is exponentially distributed with mean value $\omega_{med}=1/\beta$. The model also considers…

种群与进化 · 定量生物学 2009-11-10 Viviane M. de Oliveira , Paulo R. A. Campos

In evolutionary game dynamics, reproductive success increases with the performance in an evolutionary game. If strategy $A$ performs better than strategy $B$, strategy $A$ will spread in the population. Under stochastic dynamics, a single…

种群与进化 · 定量生物学 2009-03-06 Philipp M. Altrock , Arne Traulsen

Evolutionary games on graphs describe how strategic interactions and population structure determine evolutionary success, quantified by the probability that a single mutant takes over a population. Graph structures, compared to the…

种群与进化 · 定量生物学 2017-05-08 Philipp M. Altrock , Arne Traulsen , Martin A. Nowak

A mutator is an allele that increases the mutation rate throughout the genome by disrupting some aspect of DNA replication or repair. Mutators that increase the mutation rate by the order of 100 fold have been observed to spontaneously…

种群与进化 · 定量生物学 2008-12-31 C. Scott Wylie , Cheol-Min Ghim , David A. Kessler , Herbert Levine

We consider a model of a population with fixed size $N$, which is subjected to an unlimited supply of beneficial mutations at a constant rate $\mu_N$. Individuals with $k$ beneficial mutations have the fitness $(1+s_N)^k$. Each individual…

概率论 · 数学 2024-12-30 Nantawat Udomchatpitak , Jason Schweinsberg

Evolutionary dynamics on graphs can lead to many interesting and counterintuitive findings. We study the Moran process, a discrete time birth-death process, that describes the invasion of a mutant type into a population of wild-type…

种群与进化 · 定量生物学 2015-04-23 Laura Hindersin , Arne Traulsen

We study fixation probabilities and times as a consequence of neutral genetic drift in subdivided populations, motivated by a model of the cultural evolutionary process of language change that is described by the same mathematics as the…

种群与进化 · 定量生物学 2015-05-26 R A Blythe

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

种群与进化 · 定量生物学 2013-12-19 D. B. Weissman , O. Hallatschek

How long does it take for an initially advantageous mutant to establish itself in a resident population, and what does the population composition look like then? We approach these questions in the framework of the so called Bare Bones…

概率论 · 数学 2020-08-10 J. Baker , P. Chigansky , P. Jagers , F. Klebaner

In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global…

种群与进化 · 定量生物学 2015-03-24 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

A fundamental problem in the fields of population genetics, evolution, and community ecology, is the fate of a single mutant, or invader, introduced in a finite population of wild types. For a fixed-size community of $N$ individuals, with…

种群与进化 · 定量生物学 2017-10-25 Matan Danino , Nadav M. Shnerb

Cooperative interactions pervade in a broad range of many-body populations, such as ecological communities, social organizations, and economic webs. We investigate the dynamics of a population of two equivalent species A and B that are…

种群与进化 · 定量生物学 2025-01-14 Jordi Piñero , S. Redner , Ricard Solé
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