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In plants, a subset of genes exhibit imprinting in endosperm tissue such that expression is primarily from the maternal or paternal allele. Imprinting may arise as a consequence of mechanisms for silencing of transposons during…

The evolutionary significance of hybridization and subsequent introgression has long been appreciated, but evaluation of the genome-wide effects of these phenomena has only recently become possible. Crop-wild study systems represent ideal…

Populations of widely distributed species often encounter and adapt to specific environmental conditions. However, comprehensive characterization of the genetic basis of adaptation is demanding, requiring genome-wide genotype data, multiple…

种群与进化 · 定量生物学 2013-08-01 Tanja Pyhäjärvi , Matthew B. Hufford , Sofiane Mezmouk , Jeffrey Ross-Ibarra

Most non-synonymous mutations are thought to be deleterious because of their effect on protein sequence. These polymorphisms are expected to be removed or kept at low frequency by the action of natural selection, and rare deleterious…

种群与进化 · 定量生物学 2013-08-05 Sofiane Mezmouk , Jeffrey Ross-Ibarra

Quantifying the variation in yield component traits of maize (Zea mays L.), which together determine the overall productivity of this globally important crop, plays a critical role in plant genetics research, plant breeding, and the…

Optimization of crop production requires root systems to function in water uptake, nutrient use, and anchorage. In maize, two types of nodal roots-subterranean crown and aerial brace roots function in anchorage and water uptake and…

组织与器官 · 定量生物学 2020-12-02 Ashley N. Hostetler , Rajdeep S. Khangura , Brian P. Dilkes , Erin E. Sparks

Modern maize breeding relies upon selection in inbreeding populations to improve the performance of cross-population hybrids. The United States Department of Agriculture - Agricultural Research Service reciprocal recurrent selection…

种群与进化 · 定量生物学 2015-06-29 Justin P. Gerke , Jode W. Edwards , Katherine E. Guill , Jeffrey Ross-Ibarra , Michael D. McMullen

Coupling the control of expression stochasticity (noise) to the ability of expression change (plasticity) can alter gene function and influence adaptation. A number of factors, such as transcription re-initiation, strong chromatin…

基因组学 · 定量生物学 2012-09-12 Djordje Bajić , Juan F. Poyatos

Heterosis is the improved or increased function of any biological quality in a hybrid offspring. We have studied yet the largest maize SNP dataset for traits prediction. We develop linear and non-linear models which consider relationships…

机器学习 · 统计学 2020-07-02 Binbin Shi , Xupeng Chen

It often is emphasized that gene expression is noisy. A seemingly contradictory view is that control mechanisms have been optimized to squeeze as much information as possible out of a limited number of molecules. Here we revisit these…

生物物理 · 物理学 2025-12-17 Nicholas Lawson , William Bialek

According to recent experimental evidence, the architecture of a promoter, defined as the number, strength and regulatory role of the operators that control the promoter, plays a major role in determining the level of cell-to-cell…

分子网络 · 定量生物学 2015-05-19 Alvaro Sanchez , Hernan Garcia , Daniel Jones , Rob Phillips , Jane' Kondev

Despite the greater functional importance of protein levels, our knowledge of gene expression evolution is based almost entirely on studies of mRNA levels. In contrast, our understanding of how translational regulation evolves has lagged…

基因组学 · 定量生物学 2013-12-02 Carlo G. Artieri , Hunter B. Fraser

Maize is a highly nutritional cereal widely used for human and animal consumption and also as raw material by the biofuels industries. This highlights the importance of precisely quantifying the corn grain productivity in season, helping…

计算机视觉与模式识别 · 计算机科学 2023-06-13 Felipe Araújo , Igor Gadelha , Rodrigo Tsukahara , Luiz Pita , Filipe Costa , Igor Vaz , Andreza Santos , Guilherme Fôlego

Heritable differences in gene expression between individuals are an important source of phenotypic variation. The question of how closely the effects of genetic variation on protein levels mirror those on mRNA levels remains open. Here, we…

基因组学 · 定量生物学 2014-09-04 Frank W. Albert , Dale Muzzey , Jonathan Weissman , Leonid Kruglyak

Transgenerational inheritance of a trait is presumably affected by both genetic and environmental factors but remains poorly understood. We studied the effect of genetic polymorphisms on transgenerational inheritance of yeast segregants…

基因组学 · 定量生物学 2019-04-04 Zuobin Zhu , Qing Lu , Dejian Yuan , Yanke Li , Xian Man , Yueran Zhu , Shi Huang

Telomeres, the nucleoprotein complexes at the termini of linear chromosomes, are essential for the processes of end replication, end protection, and chromatin segregation. The Mre11 complex is involved in multiple cellular roles in DNA…

亚细胞过程 · 定量生物学 2018-05-01 In-Joon Baek , Daniel S Moss , Arthur J Lustig

Telomeres, the nucleoprotein complexes at the termini of linear chromosomes, are essential for the processes of end replication, end-protection, and chromatin segregation. The Mre11 complex is involved in multiple cellular roles in DNA…

亚细胞过程 · 定量生物学 2018-05-01 In Joon Baek , Daniel S. Moss , Arthur J. Lustig

The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks, whereby gene products from a single network can act to control their own…

生物物理 · 物理学 2009-11-06 Jeff Hasty , Joel Pradines , Milos Dolnik , J. J. Collins

Accurately counting maize tassels is important for monitoring the growth status of maize plants. This tedious task, however, is still mainly done by manual efforts. In the context of modern plant phenotyping, automating this task is…

计算机视觉与模式识别 · 计算机科学 2017-07-11 Hao Lu , Zhiguo Cao , Yang Xiao , Bohan Zhuang , Chunhua Shen

Grain growth experiments on thin metallic films have shown the geometric and topological characteristics of the grain structure to be universal and independent of many experimental conditions. The universal size distribution, however, is…

材料科学 · 物理学 2017-11-21 Rainer Backofen , Katayun Barmak , Ken Elder , Axel Voigt
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