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A position-dependent stochastic diffusion model of gating in ion channels is developed by considering the spatial variation of the diffusion coefficient between the closed and open states. It is assumed that a sensor which regulates the…

介观与纳米尺度物理 · 物理学 2014-07-24 Samuel Robert Vaccaro

Biochemical networks are the analog computers of life. They allow living cells to control a large number of biological processes, such as gene expression and cell signalling. In biochemical networks, the concentrations of the components are…

分子网络 · 定量生物学 2007-05-23 Jeroen S. van Zon , Pieter Rein ten Wolde

Reaction-diffusion models are widely used to study spatially-extended chemical reaction systems. In order to understand how the dynamics of a reaction-diffusion model are affected by changes in its input parameters, efficient methods for…

定量方法 · 定量生物学 2017-03-08 Christopher Lester , Christian A. Yates , Ruth E. Baker

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

分子网络 · 定量生物学 2019-07-11 Ozan Kahramanoğulları

We consider a stochastically perturbed reaction diffusion equation in a bounded interval, with boundary conditions imposing the two stable phases at the endpoints. We investigate the asymptotic behavior of the front separating the two…

数学物理 · 物理学 2016-02-11 L. Bertini , S. Brassesco , P. Buttà

Motivated by a phenomenon of phase transition in a model of alignment of self-propelled particles, we obtain a kinetic mean-field equation which is nothing else than the Doi equation (also called Smoluchowski equation) with dipolar…

偏微分方程分析 · 数学 2013-01-18 Amic Frouvelle , Jian-Guo Liu

The goal of this work is to analyze the long-term behavior of reaction-diffusion systems arising in two-species chemical models and to identify the minimal set of modes that determine their dynamics. The models considered include, as…

偏微分方程分析 · 数学 2025-10-29 Erika Hausenblas , Tsiry Avisoa Randrianasolo

We present a multiscale approach to model diffusion in a crowded environment and its effect on the reaction rates. Diffusion in biological systems is often modeled by a discrete space jump process in order to capture the inherent noise of…

亚细胞过程 · 定量生物学 2016-03-18 Lina Meinecke

Since its introduction, some sixty years ago, the Montroll-Weiss continuous time random walk has found numerous applications due its ease of use and ability to describe both regular and anomalous diffusion. Yet, despite its broad…

统计力学 · 物理学 2023-09-14 Maxence Arutkin , Shlomi Reuveni

In this paper we study a second-order mean-field stochastic differential systems describing the movement of a particle under the influence of a time-dependent force, a friction, a mean-field interaction and a space and time-dependent…

概率论 · 数学 2022-10-10 T. C. Son , D. Q. Le , M. H. Duong

This work is devoted to the large-scale rheology of suspensions of non-Brownian inertialess rigid particles, possibly self-propelling, suspended in Stokes flow. Starting from a hydrodynamic model, we derive a semi-dilute mean-field…

偏微分方程分析 · 数学 2023-05-30 Mitia Duerinckx

We analyze a class of chemical reaction networks under mass-action kinetics and involving multiple time-scales, whose deterministic and stochastic models display qualitative differences. The networks are inspired by gene-regulatory…

分子网络 · 定量生物学 2018-01-30 Tomislav Plesa , Radek Erban , Hans G. Othmer

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

生物物理 · 物理学 2022-11-22 Tiankai Zhao , Hongyan Yuan

We consider a reaction-diffusion process with retardation. The particles, immersed in traps initially, remain inactive until another particle is annihilated spontaneously with a rate $\lambda$ at a certain point $\vec x$. In that case the…

统计力学 · 物理学 2015-06-25 Michael Schulz , Steffen Trimper , Knud Zabrocki

We present the analytical singular value decomposition of the stoichiometry matrix for a spatially discrete reaction-diffusion system on a one dimensional domain. The domain has two subregions which share a single common boundary. Each of…

定量方法 · 定量生物学 2023-11-27 Jacqueline M. Wentz , David M. Bortz

We prove a priori bounds for solutions of stochastic reaction diffusion equations with super-linear damping in the reaction term. These bounds provide a control on the supremum of solutions on any compact space-time set which only depends…

偏微分方程分析 · 数学 2018-09-24 Augustin Moinat , Hendrik Weber

In the singularly perturbed limit corresponding to a large diffusivity ratio between two components in a reaction-diffusion (RD) system, quasi-equilibrium spot patterns are often admitted, producing a solution that concentrates at a…

斑图形成与孤子 · 物理学 2015-09-22 Philippe H. Trinh , Michael J. Ward

In this paper we develop a hybrid version of the encounter-based approach to diffusion-mediated absorption at a reactive surface, which takes into account stochastic switching of a diffusing particle's conformational state. For simplicity,…

统计力学 · 物理学 2022-09-21 Paul C. Bressloff

Various biological cells secrete diffusing chemical compounds into their environment for communication purposes. Secretion usually takes place over the cell membrane in a spatially heterogeneous manner. Mathematical models of these…

数值分析 · 数学 2025-11-20 Qiyao Peng , Sander C. Hille

We present a method that captures the fluctuations beyond mean field in chemical reactions in the regime of small copy numbers and hence large fluctuations, using self-consistently determined memory: by integrating information from the past…

统计力学 · 物理学 2023-05-02 Moshir Harsh , Peter Sollich