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Systems consisting of a single ordinary differential equation coupled with one reaction-diffusion equation in a bounded domain and with the Neumann boundary conditions are studied in the case of particular nonlinearities from the…

偏微分方程分析 · 数学 2022-07-01 Szymon Cygan , Anna Marciniak-Czochra , Grzegorz Karch

We study a stochastic model of gene expression, in which protein production has a form of random bursts whose size distribution is arbitrary, whereas protein decay is a first-order reaction. We find exact analytical expressions for the time…

生物物理 · 物理学 2016-09-21 Jakub Jędrak , Anna Ochab-Marcinek

Communication between single cells or higher organisms by means of diffusive compounds is an important phenomenon in biological systems. Modelling therefore often occurs, most straightforwardly by a diffusion equation with suitable flux…

偏微分方程分析 · 数学 2025-05-19 Xiao Yang , Qiyao Peng , Sander C. Hille

In this article we formulate new models for coupled systems of bulk-surface reaction-diffusion equations on stationary volumes. The bulk reaction-diffusion equations are coupled to the surface reaction-diffusion equations through linear…

偏微分方程分析 · 数学 2015-06-23 Anotida Madzvamuse , Andy H. W. Chung , Chandrasekhar Venkataraman

Reaction-Diffusion systems arise in diverse areas of science and engineering. Due to the peculiar characteristics of such equations, analytic solutions are usually not available and numerical methods are the main tools for approximating the…

数值分析 · 数学 2024-09-16 Eddel Elí Ojeda Avilés , Jae-Hun Jung , Daniel Olmos Liceaga

In a reaction-diffusion system, fluctuations in both diffusion and reaction events, have important effects on the steady-state statistics of the system. Here, we argue through extensive lattice simulations, mean-field type arguments, and…

软凝聚态物质 · 物理学 2013-06-12 Fernando Peruani , Chiu Fan Lee

Stochasticity in gene expression can give rise to fluctuations in protein levels and lead to phenotypic variation across a population of genetically identical cells. Recent experiments indicate that bursting and feedback mechanisms play…

分子网络 · 定量生物学 2015-06-22 Niraj Kumar , Thierry Platini , Rahul V. Kulkarni

Subdiffusion has been proposed as an explanation of various kinetic phenomena inside living cells. In order to fascilitate large-scale computational studies of subdiffusive chemical processes, we extend a recently suggested mesoscopic model…

偏微分方程分析 · 数学 2018-02-19 Emilie Blanc , Stefan Engblom , Andreas Hellander , Per Lötstedt

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

定量方法 · 定量生物学 2025-01-24 Anil Cengiz , Sean D Lawley

We analyze a coupled system of evolution equations that describes the effect of thermal gradients on the motion and deposition of $N$ populations of colloidal species diffusing and interacting together through Smoluchowski production terms.…

偏微分方程分析 · 数学 2014-06-05 Oleh Krehel , Adrian Muntean

We construct path integrals for stochastic hybrid reaction-diffusion (RD) processes, in which the reaction terms depend on the discrete state of a randomly switching environment. We proceed by spatially discretizing a given RD system and…

统计力学 · 物理学 2021-10-15 Paul C. Bressloff

The activity of catalytic materials is reduced during operation by several mechanisms, one of them being poisoning of catalytic sites by chemisorbed impurities or products. Here we study the effects of poisoning in two reaction-diffusion…

统计力学 · 物理学 2015-05-13 T. G. Mattos , Fabio D. A. Aarao Reis

Anderson, Craciun, and Kurtz have proved that a stochastically modelled chemical reaction system with mass-action kinetics admits a stationary distribution when the deterministic model of the same system with mass-action kinetics admits an…

数学物理 · 物理学 2017-08-22 John C. Baez , Brendan Fong

Model-based prediction of stochastic noise in biomolecular reactions often resorts to approximation with unknown precision. As a result, unexpected stochastic fluctuation causes a headache for the designers of biomolecular circuits. This…

分子网络 · 定量生物学 2018-08-07 Yuta Sakurai , Yutaka Hori

Hypothesis:Diffusion in confinement is an important fundamental problem with significant implications for applications of supported liquid phases. However, resolving the spatially dependent diffusion coefficient, parallel and perpendicular…

We prove the existence and uniqueness of a strong solution of a stochastic differential equation with normal reflection representing the random motion of finitely many globules. Each globule is a sphere with time-dependent random radius and…

概率论 · 数学 2010-02-16 Myriam Fradon

Reaction-diffusion processes can be adopted to model a large number of dynamics on complex networks, such as transport processes or epidemic outbreaks. In most cases, however, they have been studied from a fermionic perspective, in which…

统计力学 · 物理学 2008-10-21 Andrea Baronchelli , Michele Catanzaro , Romualdo Pastor-Satorras

Open biochemical systems of interacting molecules are ubiquitous in life-related processes. However, established computational methodologies, like molecular dynamics, are still mostly constrained to closed systems and timescales too small…

定量方法 · 定量生物学 2025-10-15 Margarita Kostré , Christof Schütte , Frank Noé , Mauricio J. del Razo

Space and time scales are not independent in diffusion. In fact, numerical simulations show that different patterns are obtained when space and time steps ($\Delta x$ and $\Delta t$) are varied independently. On the other hand, anisotropy…

patt-sol · 物理学 2015-06-26 Rui Dilao , Joaquim Sainhas

The reaction-diffusion master equation (RDME) is commonly used to model processes where both the spatial and stochastic nature of chemical reactions need to be considered. We show that the RDME in many cases is inconsistent with a…

定量方法 · 定量生物学 2009-05-29 Paul Sjoberg , Otto G Berg , Johan Elf
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