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We present a unifying approach to multiple testing procedures for sequential (or streaming) data by giving sufficient conditions for a sequential multiple testing procedure to control the familywise error rate (FWER), extending to the…

统计方法学 · 统计学 2015-02-25 Jay Bartroff , Jinlin Song

This paper addresses the following general scenario: A scientist wishes to perform a battery of experiments, each generating a sequential stream of data, to investigate some phenomenon. The scientist would like to control the overall error…

统计方法学 · 统计学 2014-05-12 Jay Bartroff , Jinlin Song

A classical approach for dealing with the multiple testing problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of at least one false rejection. In many applications, one might be…

统计理论 · 数学 2008-10-29 Wenge Guo , M. Bhaskara Rao

In this paper, we consider the problem of simultaneously testing many two-sided hypotheses when rejections of null hypotheses are accompanied by claims of the direction of the alternative. The fundamental goal is to construct methods that…

统计理论 · 数学 2017-03-21 Anjana Grandhi , Wenge Guo , Joseph P. Romano

We propose a general, modular method for significance testing of groups (or clusters) of variables in a high-dimensional linear model. In presence of high correlations among the covariables, due to serious problems of identifiability, it is…

统计理论 · 数学 2015-02-12 Jacopo Mandozzi , Peter Bühlmann

The closure and the partitioning principles have been used to build various multiple testing procedures in the past three decades. The essence of these two principles is based on parameter space partitioning. In this article, we propose a…

统计方法学 · 统计学 2019-11-20 Huajiang Li , Hong Zhou

Conventional multiple hypothesis tests use step-up, step-down, or closed testing methods to control the overall error rates. We will discuss marrying these methods with adaptive multistage sampling rules and stopping rules to perform…

统计方法学 · 统计学 2011-07-12 Jay Bartroff , Tze Leung Lai

We present a novel necessary and sufficient principle for multiple testing methods controlling an expected loss. This principle asserts that every such multiple testing method is a special case of a general closed testing procedure based on…

统计方法学 · 统计学 2026-01-05 Ziyu Xu , Aldo Solari , Lasse Fischer , Rianne de Heide , Aaditya Ramdas , Jelle Goeman

We present a procedure for controlling FWER when sequentially considering successive subfamilies of null hypotheses and rejecting at most one from each subfamily. Our procedure differs from previous procedures for controlling FWER by…

统计方法学 · 统计学 2017-02-15 Geoffrey I. Webb , Mark van der Laan

We consider a multiple hypothesis testing setting where the hypotheses are ordered and one is only permitted to reject an initial contiguous block, H_1,\dots,H_k, of hypotheses. A rejection rule in this setting amounts to a procedure for…

The closure principle is fundamental in multiple testing and has been used to derive many efficient procedures with familywise error rate control. However, it is often unsuitable for modern research, which involves flexible multiple testing…

统计方法学 · 统计学 2024-05-27 Lasse Fischer , Marta Bofill Roig , Werner Brannath

Consider the problem of testing $s$ hypotheses simultaneously. The usual approach restricts attention to procedures that control the probability of even one false rejection, the familywise error rate (FWER). If $s$ is large, one might be…

统计理论 · 数学 2007-11-06 Joseph P. Romano , Michael Wolf

Consider the multiple testing problem of testing null hypotheses $H_1,...,H_s$. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($\mathit{FWER}$),…

统计理论 · 数学 2007-06-13 Joseph P. Romano , Azeem M. Shaikh

Consider the problem of simultaneously testing null hypotheses H_1,...,H_s. The usual approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of…

统计理论 · 数学 2007-06-13 E. L. Lehmann , Joseph P. Romano

We propose a general and flexible procedure for testing multiple hypotheses about sequential (or streaming) data that simultaneously controls both the false discovery rate (FDR) and false nondiscovery rate (FNR) under minimal assumptions…

统计方法学 · 统计学 2019-01-14 Jay Bartroff , Jinlin Song

The sequential multiple testing problem is considered under two generalized error metrics. Under the first one, the probability of at least $k$ mistakes, of any kind, is controlled. Under the second, the probabilities of at least $k_1$…

统计理论 · 数学 2019-02-18 Yanglei Song , Georgios Fellouris

In this paper, the problem of error control of stepwise multiple testing procedures is considered. For two-sided hypotheses, control of both type 1 and type 3 (or directional) errors is required, and thus mixed directional familywise error…

统计理论 · 数学 2016-02-10 Wenge Guo , Joseph P. Romano

Simultaneous statistical inference has been a cornerstone in the statistics methodology literature because of its fundamental theory and paramount applications. The mainstream multiple testing literature has traditionally considered two…

统计理论 · 数学 2025-03-21 Monitirtha Dey , Subir Kumar Bhandari

The $\gamma$-FDP and $k$-FWER multiple testing error metrics, which are tail probabilities of the respective error statistics, have become popular recently as less-stringent alternatives to the FDR and FWER. We propose general and flexible…

统计方法学 · 统计学 2016-12-20 Jay Bartroff

In a multiple testing problem where one is willing to tolerate a few false rejections, procedure controlling the familywise error rate (FWER) can potentially be improved in terms of its ability to detect false null hypotheses by…

统计理论 · 数学 2008-12-18 Sanat K. Sarkar
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