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Cells rely on the ability to sense and respond to small spatial differences in chemoattractant concentrations for survival. There is growing evidence that this is accomplished by setting the signaling system near the threshold for…

细胞行为 · 定量生物学 2022-05-19 Debojyoti Biswas , Parijat Banerjee , Pablo A. Iglesias

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

神经元与认知 · 定量生物学 2016-05-04 Ryan Pyle , Robert Rosenbaum

We study a rate-model neural network composed of excitatory and inhibitory neurons in which neuronal input-output functions are power laws with a power greater than 1, as observed in primary visual cortex. This supralinear input-output…

神经元与认知 · 定量生物学 2015-03-20 Yashar Ahmadian , Daniel B. Rubin , Kenneth D. Miller

The properties of a front between two different phases in the presence of a smoothly inhomogeneous external field that takes its critical value at the crossing point is analyzed. Two generic scenarios are studied. In the first, the system…

斑图形成与孤子 · 物理学 2015-08-17 Haim Weissmann , Nadav M. Shnerb , David A. Kessler

We study numerically and analytically first- and second-order phase transitions in neuronal networks stimulated by shot noise (a flow of random spikes bombarding neurons). Using an exactly solvable cortical model of neuronal networks on…

神经元与认知 · 定量生物学 2015-08-25 K. -E. Lee , M. A. Lopes , J. F. F. Mendes , A. V. Goltsev

We theoretically investigate the flow of the atomic excitations in a driven chiral-coupled atomic chain with nonreciprocal decay channels. This one-dimensional system allows infinite-range dipole-dipole interaction, and enables directional…

量子物理 · 物理学 2019-03-06 H. H. Jen

We devised a measure based on the distributions of relative event timings of two coupled units. The measure dynamically evaluates temporal interdependencies between the two coupled units. Using this we show that even in the event of…

混沌动力学 · 物理学 2007-05-23 Michal Zochowski , Rhonda Dzakpasu

We analyze a class of network motifs in which a short, two-node positive feed- back motif is inserted in a three-node negative feedback loop. We demonstrate that such networks can undergo a bifurcation to a state where a stable fixed point…

分子网络 · 定量生物学 2012-09-10 Weihan Li , Sandeep Krishna , Simone Pigolotti , Namiko Mitarai , Mogens H. Jensen

In order to describe excitable reaction-diffusion systems, we derive a two-dimensional model with a Hopf and a semilocal saddle-node homoclinic bifurcation. This model gives the theoretical framework for the analysis of the saddle-node…

数学物理 · 物理学 2007-05-23 Rui Dilao , Andras Volford

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

生物物理 · 物理学 2017-05-09 Marat M. Rvachev

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

无序系统与神经网络 · 物理学 2020-03-11 Takashi Hayakawa , Tomoki Fukai

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

神经元与认知 · 定量生物学 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Networks of excitatory and inhibitory neurons display asynchronous irregular (AI) states, where the activities of the two populations are balanced. At the single cell level, it was shown that neurons subject to balanced and noisy synaptic…

神经元与认知 · 定量生物学 2016-11-29 Zahara Girones , Alain Destexhe

We undertake a fundamental study of network equilibria modeled as solutions of fixed point equations for monotone linear functions with saturation nonlinearities. The considered model extends one originally proposed to study systemic risk…

动力系统 · 数学 2021-01-19 Leonardo Massai , Giacomo Como , Fabio Fagnani

We investigate a conductance-based neuron model to explore how voltage-gated ion channel isoforms influence action-potential generation. The model combines a six-state Markov representation of NaV channels with a first-order KV3.1 model,…

神经元与认知 · 定量生物学 2025-12-03 Youssof Abdullah , Violet Hart , Moumita Das

We analyze a microscopic RNA model, which includes two widely used models as limiting cases, namely it contains terms for bond as well as for stacking energies. We numerically investigate possible changes in the qualitative and quantitative…

定量方法 · 定量生物学 2009-11-10 Bernd Burghardt , Alexander K. Hartmann

Problems with artificial neural networks originate from their deterministic nature and inevitable prior learnings, resulting in inadequate adaptability against unpredictable, abrupt environmental change. Here we show that a stochastically…

无序系统与神经网络 · 物理学 2009-11-13 Naoki Asakawa , Yasushi Hotta , Teruo Kanki , Hitoshi Tabata , Tomoji Kawai

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

神经元与认知 · 定量生物学 2017-07-20 Guillem Via

In computer simulations of spiking neural networks, often it is assumed that every two neurons of the network are connected by a probability of 2\%, 20\% of neurons are inhibitory and 80\% are excitatory. These common values are based on…

神经元与认知 · 定量生物学 2015-03-06 Hamed Seyed-allaei