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In the first part of this paper, we propose new optimization-based methods for the computation of preferred (dense, sparse, reversible, detailed and complex balanced) linearly conjugate reaction network structures with mass action dynamics.…

动力系统 · 数学 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

动力系统 · 数学 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics. The original problem…

动力系统 · 数学 2011-07-05 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

This paper presents new results about the optimization based generation of chemical reaction networks (CRNs) of higher deficiency. Firstly, it is shown that the graph structure of the realization containing the maximal number of reactions…

分子网络 · 定量生物学 2011-03-23 Gabor Szederkenyi , Katalin M. Hangos , Tamas Peni

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics.

动力系统 · 数学 2015-03-19 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

We further clarify the relation between detailed-balanced and complex-balanced equilibria of reversible chemical reaction networks. Our results hold for arbitrary kinetics and also for boundary equilibria. Detailed balance, complex balance,…

动力系统 · 数学 2020-09-29 Stefan Müller , Badal Joshi

The principle of detailed balance states that in equilibrium each elementary process is equilibrated by its reverse process. For many real physico-chemical complex systems (e.g. homogeneous combustion, heterogeneous catalytic oxidation,…

统计力学 · 物理学 2011-08-24 A. N. Gorban , G. S. Yablonsky

The induced kinetic differential equation of a reaction network endowed with mass action type kinetics is a system of polynomial differential equations. The problem studied here is: Given a polynomial differential equation, is it possible…

动力系统 · 数学 2019-09-10 G. Craciun , M. D. Johnston , G. Szederkényi , E. Tonello , J. Tóth , P. Y. Yu

A numerically effective procedure for determining weakly reversible chemical reaction networks that are linearly conjugate to a known reaction network is proposed in this paper. The method is based on translating the structural and…

动力系统 · 数学 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Mass-action kinetics is frequently used in systems biology to model the behaviour of interacting chemical species. Many important dynamical properties are known to hold for such systems if they are weakly reversible and have a low…

动力系统 · 数学 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Motivated by recent progress on the interplay between graph theory, dynamics, and systems theory, we revisit the analysis of chemical reaction networks described by mass action kinetics. For reaction networks possessing a thermodynamic…

最优化与控制 · 数学 2012-06-19 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

The convergence to equilibrium of mass action reaction-diffusion systems arising from networks of chemical reactions is studied. The considered reaction networks are assumed to satisfy the detailed balance condition and have no boundary…

偏微分方程分析 · 数学 2017-02-13 Klemens Fellner , Bao Quoc Tang

Detailed balance of a chemical reaction network can be defined in several different ways. Here we investigate the relationship among four types of detailed balance conditions: deterministic, stochastic, local, and zero-order local detailed…

概率论 · 数学 2021-01-27 Chen Jia , Da-Quan Jiang , Youming Li

The characterization of the notions of complex and detailed balancing for mass action kinetics chemical reaction networks is revisited from the perspective of algebraic graph theory, in particular Kirchhoff's Matrix Tree theorem for…

动力系统 · 数学 2015-03-09 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and…

经典分析与常微分方程 · 数学 2025-02-10 E. Franco , J. J. L. Velázquez

A crisp survey is given of chemical reaction networks from the perspective of general nonlinear network dynamics, in particular of consensus dynamics. It is shown how by starting from the complex-balanced assumption the reaction dynamics…

动力系统 · 数学 2015-02-10 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

Chemical reaction network theory is a powerful framework to describe and analyze chemical systems. While much about the concentration profile in an equilibrium state can be determined in terms of the graph structure, the overall reaction's…

分子网络 · 定量生物学 2024-02-29 Tomoharu Suda

The aim of this article is to build on the use of tools from computational algebra initiated in Craciun, Dickenstein, Shiu, Sturmfels (JSC, 2009), for the study of general kinetic systems, which have a wide range of applications in…

动力系统 · 数学 2010-01-07 Alicia Dickenstein , Mercedes Perez Millan

In this paper, we provide a detailed theoretical analysis of the numerical scheme introduced in J. Comput. Phys. 436 (2021) 110253 for the reaction kinetics of a class of chemical reaction networks that satisfies detailed balance condition.…

数值分析 · 数学 2024-02-07 Chun Liu , Cheng Wang , Yiwei Wang

The use of mathematical methods for the analysis of chemical reaction systems has a very long history, and involves many types of models: deterministic versus stochastic, continuous versus discrete, and homogeneous versus spatially…

分子网络 · 定量生物学 2018-05-29 Polly Y. Yu , Gheorghe Craciun
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