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We study a class of growth algorithms for directed graphs that are candidate models for the evolution of genetic regulatory networks. The algorithms involve partial duplication of nodes and their links, together with innovation of new…

分子网络 · 定量生物学 2007-05-23 D. V. Foster , S. A. Kauffman , J. E. S. Socolar

The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

概率论 · 数学 2012-11-30 Elchanan Mossel , Sebastien Roch

Evolving multiplex networks are a powerful model for representing the dynamics along time of different phenomena, such as social networks, power grids, biological pathways. However, exploring the structure of the multiplex network time…

物理与社会 · 物理学 2016-01-11 Giuseppe Jurman

A rooted phylogenetic network is a directed acyclic graph with a single root, whose sinks correspond to a set of species. As such networks are useful for representing the evolution of species that have undergone reticulate evolution, there…

种群与进化 · 定量生物学 2022-06-28 Vincent Moulton , Taoyang Wu

A wide range of applications and research has been done with genome-scale metabolic models. In this work we describe a methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this…

分子网络 · 定量生物学 2026-02-06 D. Gamermann , A. Montagud , J. A. Conejero , P. F. de Córdoba , J. F. Urchieguía

Phylogenetic networks provide a general framework for modeling reticulate evolutionary processes such as hybridization, recombination, and horizontal gene transfer. In this paper, we study the asymptotic counting of binary phylogenetic…

种群与进化 · 定量生物学 2026-05-25 Hao Yu , Louxin Zhang

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees…

种群与进化 · 定量生物学 2009-10-19 Leo van Iersel , Steven Kelk , Regula Rupp , Daniel Huson

Orchards are a biologically relevant class of phylogenetic networks as they can describe treelike evolutionary histories augmented with horizontal transfer events. Moreover, the class has attractive mathematical characterizations that can…

种群与进化 · 定量生物学 2024-09-24 Jordan Dempsey , Leo van Iersel , Mark Jones , Yukihiro Murakami , Norbert Zeh

A metric graph is a 1-dimensional stratified metric space consisting of vertices and edges or loops glued together. Metric graphs can be naturally used to represent and model data that take the form of noisy filamentary structures, such as…

统计理论 · 数学 2014-02-10 Fabrizio Lecci , Alessandro Rinaldo , Larry Wasserman

Multiplex networks are collections of networks with identical nodes but distinct layers of edges. They are genuine representations for a large variety of real systems whose elements interact in multiple fashions or flavors. However,…

物理与社会 · 物理学 2024-02-27 Daniel Kaiser , Siddharth Patwardhan , Minsuk Kim , Filippo Radicchi

Complex networks are an important paradigm of modern complex systems sciences which allows quantitatively assessing the structural properties of systems composed of different interacting entities. During the last years, intensive efforts…

In recent years, there has been an effort to extend the classical notion of phylogenetic balance, originally defined in the context of trees, to networks. One of the most natural ways to do this is with the so-called $B_2$ index. In this…

种群与进化 · 定量生物学 2024-07-30 François Bienvenu , Jean-Jil Duchamps , Michael Fuchs , Tsan-Cheng Yu

Many methods have been developed for finding the commonalities between different organisms to study their phylogeny. The structure of metabolic networks also reveal valuable insights into metabolic capacity of species as well as into the…

分子网络 · 定量生物学 2016-04-08 Krishanu Deyasi , Anirban Banerjee , Bony Deb

In evolutionary studies it is common to use phylogenetic trees to represent the evolutionary history of a set of species. However, in case the transfer of genes or other genetic information between the species or their ancestors has…

组合数学 · 数学 2022-02-15 Katharina T. Huber , Vincent Moulton , Guillaume E. Scholz

Arboreal networks are multi-rooted phylogenetic networks whose underlying graph is a tree. We give an encoding of stack-free arboreal networks in terms of triplets and the novel concept of a duet. This yields a polynomial time algorithm to…

离散数学 · 计算机科学 2026-05-05 Katharina T. Huber , Katherine St. John

Networks are important representations in computer science to communicate structural aspects of a given system of interacting components. The evolution of a network has several topological properties that can provide us information on the…

社会与信息网络 · 计算机科学 2020-04-30 Joao Pita Costa , Tihana Galinac Grbac

Rooted acyclic graphs appear naturally when the phylogenetic relationship of a set $X$ of taxa involves not only speciations but also recombination, horizontal transfer, or hybridization, that cannot be captured by trees. A variety of…

种群与进化 · 定量生物学 2022-04-29 Marc Hellmuth , David Schaller , Peter F. Stadler

We introduce a framework for network analysis based on random walks on directed acyclic graphs where the probability of passing through a given node is the key ingredient. We illustrate its use in evaluating the mutual influence of nodes…

物理与社会 · 物理学 2011-10-10 Stanislao Gualdi , Matus Medo , Yi-Cheng Zhang

Node similarity is a significant property driving the growth of real networks. In this paper, based on the observed spreading results we apply the node similarity metrics to reconstruct propagation networks. We find that the reconstruction…

物理与社会 · 物理学 2014-10-01 Hao Liao , An Zeng