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Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

最优化与控制 · 数学 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

统计计算 · 统计学 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

应用统计 · 统计学 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

机器学习 · 统计学 2015-03-02 Shaurabh Nandy , Richard M. Golden

The brain can be regarded as a network: a connected system where nodes, or units, represent different specialized regions and links, or connections, represent communication pathways. From a functional perspective communication is coded by…

神经元与认知 · 定量生物学 2014-09-10 Fabrizio De Vico Fallani , Jonas Richiardi , Mario Chavez , Sophie Achard

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

神经元与认知 · 定量生物学 2013-04-16 Gaël Varoquaux , R. C. Craddock

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

统计方法学 · 统计学 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

定量方法 · 定量生物学 2016-02-03 Sean L. Simpson , Paul J. Laurienti

Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…

神经元与认知 · 定量生物学 2014-09-24 Enzo Tagliazucchi , Helmut Laufs , Dante R. Chialvo

Brain connectivity analysis is now at the foreground of neuroscience research. A connectivity network is characterized by a graph, where nodes represent neural elements such as neurons and brain regions, and links represent statistical…

统计方法学 · 统计学 2015-11-04 Yin Xia , Lexin Li

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

统计方法学 · 统计学 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

神经元与认知 · 定量生物学 2020-10-06 Richard Betzel

Real-world networks often benefit from capturing both local and global interactions. Inspired by multi-modal analysis in brain imaging, where structural and functional connectivity offer complementary views of network organization, we…

神经与进化计算 · 计算机科学 2025-08-11 Yang Li , Luopeiwen Yi , Tananun Songdechakraiwut

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

神经元与认知 · 定量生物学 2011-12-23 Marcus Kaiser

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

神经元与认知 · 定量生物学 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

统计计算 · 统计学 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

The brain is often studied from a network perspective, where functional activity is assessed using functional Magnetic Resonance Imaging (fMRI) to estimate connectivity between predefined neuronal regions. Functional connectivity can be…

应用统计 · 统计学 2025-07-22 Olivier Bisson , Yanis Aeschlimann , Samuel Deslauriers-Gauthier , Xavier Pennec

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

物理与社会 · 物理学 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

神经元与认知 · 定量生物学 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Understanding brain connectivity in a network-theoretic context has shown much promise in recent years. This type of analysis identifies brain organisational principles, bringing a new perspective to neuroscience. At the same time, large…

神经与进化计算 · 计算机科学 2016-11-28 Sarah Parisot , Jonathan Passerat-Palmbach , Markus D. Schirmer , Boris Gutman