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Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

神经元与认知 · 定量生物学 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure…

神经与进化计算 · 计算机科学 2014-07-16 Axel Wismüller , Xixi Wang , Adora M. DSouza , Mahesh B. Nagarajan

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

机器学习 · 计算机科学 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

计算机视觉与模式识别 · 计算机科学 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

The functional network approach, where fMRI BOLD time series are mapped to networks depicting functional relationships between brain areas, has opened new insights into the function of the human brain. In this approach, the choice of…

神经元与认知 · 定量生物学 2017-11-10 Onerva Korhonen , Heini Saarimäki , Enrico Glerean , Mikko Sams , Jari Saramäki

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

统计方法学 · 统计学 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

定量方法 · 定量生物学 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

In functional MRI (fMRI), effective connectivity analysis aims at inferring the causal influences that brain regions exert on one another. A common method for this type of analysis is structural equation modeling (SEM). We here propose a…

定量方法 · 定量生物学 2024-09-10 G. Marrelec , A. Giron

The human brain forms functional networks on all spatial scales. Modern fMRI scanners allow to resolve functional brain data in high resolutions, allowing to study large-scale networks that relate to cognitive processes. The analysis of…

神经元与认知 · 定量生物学 2019-05-14 Melanie Weber , Johannes Stelzer , Emil Saucan , Alexander Naitsat , Gabriele Lohmann , Jürgen Jost

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

神经与进化计算 · 计算机科学 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

神经元与认知 · 定量生物学 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Functional magnetic resonance imaging (fMRI) has been commonly used to construct functional connectivity networks (FCNs) of the human brain. TFCNs are primarily limited to quantifying pairwise relationships between ROIs ignoring higher…

信号处理 · 电气工程与系统科学 2025-07-15 Duc Vu , Selin Aviyente

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

神经元与认知 · 定量生物学 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Predicting disease states from functional brain connectivity is critical for the early diagnosis of severe neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease. Existing studies commonly employ Graph Neural…

机器学习 · 计算机科学 2025-04-22 David Yang , Mostafa Abdelmegeed , John Modl , Minjeong Kim

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

统计方法学 · 统计学 2016-03-22 Jichun Xie , Jian Kang

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

神经元与认知 · 定量生物学 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart

This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

统计计算 · 统计学 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

Population analyses of functional connectivity have provided a rich understanding of how brain function differs across time, individual, and cognitive task. An important but challenging task in such population analyses is the identification…

社会与信息网络 · 计算机科学 2020-08-19 James D. Wilson , Melanie Baybay , Rishi Sankar , Paul Stillman , Abbie M. Popa