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A DNA-protein complex modelled by a semiflexible chain and an attractive spherical core is studied in the situation when an external stretching force is acting on one end monomer of the chain while the other end monomer is kept fixed in…

软凝聚态物质 · 物理学 2009-11-10 Takahiro Sakaue , Hartmut Löwen

Dynamics of nucleosomes, the building blocks of the chromatin, has crucial effects on expression, replication and repair of genomes in eukaryotes. Beside constant movements of nucleosomes by thermal fluctuations, ATP-dependent chromatin…

生物大分子 · 定量生物学 2020-01-28 Fatemeh Khodabandeh , Hashem Fatemi , Farshid Mohammad-Rafiee1

Magnetic tweezers are used to study the mechanical response under torsion of single nucleosome arrays reconstituted on tandem repeats of 5S positioning sequences. Regular arrays are extremely resilient and can reversibly accommodate a large…

The theory of nematic-smectic phase transition in the system of uniform semi-flexible chains with hard-core repulsion is presented. Both the general density-functional formalism the tube-model calculation show that the flexibility of the…

软凝聚态物质 · 物理学 2009-10-31 Alexei V. Tkachenko

Nucleosomes form the basic unit of compaction within eukaryotic genomes and their locations represent an important, yet poorly understood, mechanism of genetic regulation. Quantifying the strength of interactions within the nucleosome is a…

生物物理 · 物理学 2016-08-25 Joshua Lequieu , Andres Cordoba , David C. Schwartz , Juan J. de Pablo

We investigate the folding and forced-unbinding transitions of adsorbed semiflexible polymer chains using theory and simulations. These processes describe biologically relevant phenomena that include adhesive interactions between proteins…

软凝聚态物质 · 物理学 2007-05-23 V. Barsegov , D. Thirumalai

Using molecular dynamics simulations we examine the dynamics of a family of model polymers with varying chain length and torsional potential barriers. We focus on features of the dynamics of polymers that are seen experimentally but absent…

软凝聚态物质 · 物理学 2019-06-11 Daniel Fragiadakis , C. Michael Roland

The fracture and severing of polymer chains plays a critical role in the failure of fibrous materials and the regulated turnover of intracellular filaments. Using continuum wormlike chain models, we investigate the fracture of semiflexible…

统计力学 · 物理学 2020-03-05 Alexander Lorenzo , Enrique M. De La Cruz , Elena F. Koslover

In recent past, experiments and simulations have suggested that apart from the solvent friction, friction arising from the protein itself plays an important role in protein folding by affecting the intra-chain loop formation dynamics. This…

软凝聚态物质 · 物理学 2014-06-25 Nairhita Samanta , Jayanta Ghosh , Rajarshi Chakrabarti

Chromatin looping is a major epigenetic regulatory mechanism in higher eukaryotes. Besides its role in transcriptional regulation, chromatin loops have been proposed to play a pivotal role in the segregation of entire chromosomes. The…

软凝聚态物质 · 物理学 2015-05-18 Manfred Bohn , Dieter W. Heermann

The competition between external drives and interparticle interactions are important for the static and dynamic properties of topological quasiparticles in confined geometries. Here, we study the dynamics of particlelike skyrmions under a…

介观与纳米尺度物理 · 物理学 2022-05-04 Xichao Zhang , Jing Xia , Xiaoxi Liu

Recent advances in electron spin resonance techniques have allowed the manipulation of the spin of individual atoms, making magnetic atomic chains on superconducting hosts one of the most promising platform where topological…

The effect of a finite torque on semiflexible polymers in a confined environment is investigated. It is shown how a new lengthscale appears in the strongly confined limit. The influence of a torque on the extension of biopolymers in…

软凝聚态物质 · 物理学 2013-01-18 Marc Emanuel

In this work, we investigate thermodynamic properties of the one-dimensional (1D) spin-crossover molecular chain being a subject of a constant external pressure. Effective compressible degenerate Ising model is used as a theoretical…

统计力学 · 物理学 2021-07-02 Andrii Gudyma , Iurii Gudyma

Spherical confinement can act either stabilizing or destabilizing on the collapsed state of a semi-flexible polymer. General free-energy arguments suggest that the order of the unconstrained collapse transition is the distinguishing factor:…

软凝聚态物质 · 物理学 2018-11-14 Martin Marenz , Johannes Zierenberg , Wolfhard Janke

The folding transition of single, long semiflexible polymers was studied with special emphasis on the chain length effect using Monte Carlo simulations. While a relatively short chain (10-25 Kuhn segments) undergoes a large discrete…

软凝聚态物质 · 物理学 2008-05-06 Yuji Higuchi , Takahiro Sakaue , Kenichi Yoshikawa

An applied tension force changes the equilibrium conformations of a polymer chain tethered to a planar substrate and thus affects the adsorption transition as well as the coil-globule and crystallization transitions. Conversely, solvent…

软凝聚态物质 · 物理学 2015-06-22 Jutta Luettmer-Strathmann , Kurt Binder

In this work, we study the effects of torsion due to a uniform distribution of topological defects (screw dislocations) on free spin/carrier dynamics in elastic solids. When a particle moves in such a medium, the effect of the torsion…

介观与纳米尺度物理 · 物理学 2017-02-20 Anderson A. Lima , Cleverson Filgueiras , Fernando Moraes

The motion of a conducting electron in a quantum dot with one or several dislocations in the underlying crystal lattice is considered in the continuum picture, where dislocations are represented by torsion of space. The possible effects of…

介观与纳米尺度物理 · 物理学 2007-05-23 Erik Aurell

We study elasticity-driven morphological transitions of soft spherical core shell structures in which the core can be treated as an isotropic elastic continuum and the surface or shell as a tensionless liquid layer, whose elastic response…

软凝聚态物质 · 物理学 2013-11-13 Craig Fogle , Amy C. Rowat , Alex J. Levine , Joseph Rudnick
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