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The Peyrard-Bishop-Dauxois (PBD) model of DNA denaturation, although successful in the description of melting profiles, fails to predict melting entropies, unzipping forces and dynamical properties, e.g. hairpin dynamics. The paper presents…

生物物理 · 物理学 2026-04-28 Nikos Theodorakopoulos

The melting behavior of long, heterogeneous DNA chains is examined within the framework of the nonlinear lattice dynamics based Peyrard-Bishop-Dauxois (PBD) model. Data for the pBR322 plasmid and the complete T7 phage have been used to…

生物物理 · 物理学 2012-02-20 Nikos Theodorakopoulos

A simple Langevin approach is used to study stationary properties of the Peyrard-Bishop-Dauxois model for DNA, allowing known properties to be recovered in an easy way. Results are shown for the denaturation transition in homogeneous…

软凝聚态物质 · 物理学 2009-11-13 Francisco de los Santos , Omar Al Hammal , Miguel Angel Munoz

The paper uses mesoscopic, non-linear lattice dynamics based (Peyrard-Bishop-Dauxois, PBD) modeling to describe thermal properties of DNA below and near the denaturation temperature. Computationally efficient notation is introduced for the…

统计力学 · 物理学 2015-03-18 Nikos Theodorakopoulos

We report on the nature of the thermal denaturation transition of homogeneous DNA as determined from a renormalisation group analysis of the Peyrard-Bishop-Dauxois model. Our approach is based on an analogy with the phenomenon of critical…

统计力学 · 物理学 2015-05-18 Jose Manuel Romero-Enrique , Francisco de los Santos , Miguel A. Munoz

The Peyrard-Bishop DNA model describes the molecular interactions with simple potentials which allow efficient calculations of melting temperatures. However, it is based on a Hamiltonian that does not consider the helical twist or any other…

生物大分子 · 定量生物学 2020-07-16 Mateus Rodrigues Leal , Gerald Weber

In this letter, we point out the inaccurate figures in a letter by Peyrard and Bishop, who investigated the statistical mechanics of a nonlinear model for DNA denaturation. We give the correct figures.

生物物理 · 物理学 2007-05-23 Su-Long Nyeo , I-Ching Yang

The melting transition of deoxyribonucleic acid (DNA), whereby the strands of the double helix structure completely separate at a certain temperature, has been characterized using neutron scattering. A Bragg peak from B-form fibre DNA has…

As a first step in the search of an analytical study of mechanical denaturation of DNA in terms of the sequence, we study stable, stationary solutions in the discrete, finite and homogeneous Peyrard-Bishop DNA model. We find and classify…

其他定量生物学 · 定量生物学 2009-11-11 Sara Cuenda , Angel Sanchez

The onset of intermediate states (denaturation bubbles) and their role during the melting transition of DNA are studied using the Peyrard-Bishop-Daxuois model by Monte Carlo simulations with no adjustable parameters. Comparison is made with…

统计力学 · 物理学 2009-11-10 S. Ares , N. K. Voulgarakis , K. O. Rasmussen , A. R. Bishop

The local opening of DNA is an intriguing phenomenon from a statistical physics point of view, but is also essential for its biological function. For instance, the transcription and replication of our genetic code can not take place without…

生物物理 · 物理学 2009-11-13 Titus S. van Erp , Santiago Cuesta-Lopez , Michel Peyrard

Unbinding of a double-stranded DNA reduces to an unscreened long range interaction and maps on various problems. Heterogeneity renormalizes interaction. Renormalization is temperature dependent. At an unbinding transition it approaches…

统计力学 · 物理学 2007-05-23 Mark Ya. Azbel'

The phase transition of $(PolyA/PolyT)_{100}$ duplex into the denaturated state is studied in the Peyrard-Bishop-Dauxois model by the method of direct molecular-dynamical modeling. The temperature dependencies of the total energy and heat…

软凝聚态物质 · 物理学 2020-02-04 I. V. Likhachev , V. D. Lakhno

The impact of various types of external potentials to the Peyrard-Bishop DNA denaturation is investigated through statistical mechanics approach. The partition function is obtained using transfer integral method, and further the stretching…

生物物理 · 物理学 2012-06-22 A. Sulaiman , F. P. Zen , H. Alatas , L. T. Handoko

The effect of heterogeneous sequence composition on the denaturation of double stranded DNA is investigated. The resulting pair-binding energy variation is found to have a negligible effect on the critical properties of the smooth second…

统计力学 · 物理学 2009-10-30 D. Cule , T. Hwa

One-dimensional thermodynamic instabilities are phase transitions not prohibited by Landau's argument, because the energy of the domain wall (DW) which separates the two phases is infinite. Whether they actually occur in a given system of…

统计力学 · 物理学 2007-06-17 Nikos Theodorakopoulos

The Poland-Scheraga model for DNA denaturation, besides playing a central role in applications, has been widely studied in the physical and mathematical literature over the past decades. More recently a natural generalization has been…

概率论 · 数学 2017-03-31 Quentin Berger , Giambattista Giacomin , Maha Khatib

The melting curves of short heterogeneous DNA chains in solution are calculated on the basis of statistical thermodynamics and compared to experiments. The computation of the partition function is based on the Peyrard-Bishop hamiltonian,…

生物物理 · 物理学 2007-05-23 Alessandro Campa , Andrea Giansanti

Contributions to QCD non-singlet evolution kernels $P(z)$ for the DGLAP equation and $V(x,y)$ for the Brodsky-Lepage evolution equation are calculated for a certain class of diagrams which include renormalon chains. Closed expressions are…

高能物理 - 唯象学 · 物理学 2014-11-17 S. V. Mikhailov

The dynamics of the DNA denaturation is studied using the Peyrard-Bishop-Dauxois model. The denaturation rate of double stranded polymers decreases exponentially as function of length below the denaturation temperature. Above Tc, the rate…

生物物理 · 物理学 2015-06-04 Titus S. van Erp , Michel Peyrard
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