相关论文: Immune response to a malaria infection: properties…
We present a mathematical model for within host viral infections that incorporates the Crowley Martin functional response, focusing on the dynamics influenced by periodic effects. This study establishes key properties of the model,…
The toxins associated with infectious diseases are potential targets for inhibitors which have the potential for prophylactic or therapeutic use. Many antibodies have been generated for this purpose, and the objective of this study was to…
We study two simple mathematical models of the epidemic. At first, we study the repetitive infection spreading in a simplified SIRS model including the effect of the decay of the acquired immune. The model is an intermediate model of the…
We introduce and analyze a within-host dynamical model of the coevolution between rapidly mutating pathogens and the adaptive immune response. Pathogen mutation and a homeostatic constraint on lymphocytes both play a role in allowing the…
Understanding and modelling the complexity of the immune system is a challenge that is shared by the ImmunoComplexiT$^1$ thematic network from the RNSC. The immune system is a complex biological, adaptive, highly diversified, self-organized…
The revival mechanism in dormant bacteria is a puzzling and open issue. We propose a model of information diffusion on a regular grid where agents represent bacteria and their mutual interactions implement quorum sensing. Agents may have…
Transmission models for infectious diseases are typically formulated in terms of dynamics between individuals or groups with processes such as disease progression or recovery for each individual captured phenomenologically, without…
This contribution is devoted to a new model of HIV multiplication motivated by the patent of one of the authors. We take into account the antigenic diversity through what we define "antigenicity", whether of the virus or of the adapted…
We study a mathematical model of environments populated by both preys and predators, with the possibility for predators to actively compete for the territory. For this model we study existence and uniqueness of solutions, and their…
Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…
A multi-patch and multi-group modeling framework describing the dynamics of a class of diseases driven by the interactions between vectors and hosts structured by groups is formulated. Hosts' dispersal is modeled in terms of patch-residence…
In this paper, we evolve from sparsity, a key concept in robust statistics, to concepts and theoretical results of what we call the mathematics of resilience, at the interface between category theory, the theory of dynamical systems,…
Experimental manipulations perturb the neuronal activity. This phenomenon is manifested in the fMRI response. Dynamic causal model and its variants can model these neuronal responses along with the BOLD responses [1, 2, 3, 4, 5] .…
We investigate a stochastic individual-based model for the population dynamics of host-virus systems where the microbial hosts may transition into a dormant state upon contact with virions, thus evading infection. Such a contact-mediated…
A current challenge for disease modeling and public health is understanding pathogen dynamics across scales since their ecology and evolution ultimately operate on several coupled scales. This is particularly true for vector-borne diseases,…
We focus on the long term dynamics of "killing the winner" Lotka-Volterra models of marine communities consisting of bacteria, virus, and zooplankton. Under suitable conditions, it is shown that there is a unique equilibrium with all…
In this work we propose a model that represents the relation between fish ponds, the mosquito population and the transmission of malaria. It has been observed that in the Amazonic region of Acre, in the North of Brazil, fish farming is…
In this paper, we analyze the infection spreading dynamics of malware in a population of cyber nodes (i.e., computers or devices). Unlike most prior studies where nodes are reactive to infections, in our setting some nodes are active…
We present a two-species population model in a well-mixed environment where the dynamics involves, in addition to birth and death, changes due to environmental factors and inter-species interactions. The novel dynamical components are…
We consider a model of antiviral immune response proposed in the works of G.I. Marchuk. The model is described by a system of delay differential equations. The asymptotic stability of a stationary solution to the system corresponding to a…