种群与进化

The debate on the role of school closures as a mitigation strategy against the spread of Covid-19 is gaining relevance due to emerging variants in Europe. According to WHO, decisions on schools "should be guided by a risk-based approach".…

Multiple instances of Zika virus epidemic have been reported around the world in the last two decades, turning the related illness into an international concern. In this context the use of mathematical models for epidemics is of great…

The reconstruction of possible histories given a sample of genetic data in the presence of recombination and recurrent mutation is a challenging problem, but can provide key insights into the evolution of a population. We present KwARG,…

This work constructs, analyzes, and simulates a new compartmental SEIR-type model for the dynamics and potential control of the current COVID-19 pandemic. The novelty in this work is two-fold. First, the population is divided according to…

We propose a minimal model to simulate long waiting times followed by evolutionary bursts on rugged landscapes. It combines point and inversions-like mutations as sources of genetic variation. The inversions are intended to simulate one of…

Ecological selection is a major driver of community assembly. Selection is classified as stabilizing when species with intermediate trait values gain the highest reproductive success, whereas selection is considered directional when fitness…

When an epidemic spreads into a population, it is often unpractical or impossible to have a continuous monitoring of all subjects involved. As an alternative, algorithmic solutions can be used to infer the state of the whole population from…

The risk for severe illness and mortality from COVID-19 significantly increases with age. As a result, age-stratified modeling for COVID-19 dynamics is the key to study how to reduce hospitalizations and mortality from COVID-19. By taking…

In this paper, we estimate epidemiological data of the COVID-19 pandemic in Hungary using only the daily number of hospitalized patients, and applying well-known techniques from systems and control theory. We use a previously published and…

We present two different approaches for modeling the spread of the COVID-19 pandemic. Both approaches are based on the population classes susceptible, exposed, infectious, quarantined, and recovered and allow for an arbitrary number of…

Addressed in this work is the performance of five popular algorithms, which aim at assessing the dissemination dynamics of the COVID-19 disease on the basis of the time series of new confirmed cases. The tests are based on simulated data,…

India has been hit by a huge second wave of Covid-19 that started in mid-February 2021. Mumbai was amongst the first cities to see the increase. In this report, we use our agent based simulator to computationally study the second wave in…

In this note we estimate herd immunity levels for the Covid-19 epidemic using a standard SEIR system that models the disease dynamics in homogeneous populations. The results obtained are indicative of values between 80% and 90% for…

Supertree methods are tree reconstruction techniques that combine several smaller gene trees (possibly on different sets of species) to build a larger species tree. The question of interest is whether the reconstructed supertree converges…

For classic Lotka-Volterra systems governing many interacting species, we establish an exclusion principle that rules out the existence of linearly asymptotically stable steady states in subcommunitites of communities that admit a stable…

Traditional Indigenous marriage rules have been studied extensively since the mid 1800s. Despite this, they have historically been cast aside as having very little utility. This is, in large part, due to a focus on trying to understand…

The spread of African swine fever (ASF) poses a grave threat to the global swine industry. Understanding transmission dynamics, such as through mechanistic modeling, is critical for designing effective control strategies. Articles were…

This paper dwells on certain novel game-theoretic investigations in bio-mimicry, discussed from the perspectives of information asymmetry, individual utility and its optimization via strategic interactions involving co-evolving preys (e.g.,…

Subclasses of lymphocytes carry different functional roles to work together to produce an immune response and lasting immunity. Additionally to these functional roles, T and B-cell lymphocytes rely on the diversity of their receptor chains…

During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…