医学物理
Obstructive sleep apnea (OSA) is believed to contribute significantly to atrial fibrillation (AF) development in certain patients. Recent studies indicate a rising risk of AF with increasing OSA severity. However, the commonly used…
Time-dependent diffusion MRI enables the estimation of water exchange rates in vivo, yet reported values in grey matter remain inconsistent. While most studies attribute these estimates to membrane permeability, non-permeative geometric…
Ultra-Low Field (ULF) MRI scanners offer a portable and cost-effective alternative to conventional MRI systems, but require careful calibration to compensate for reduced magnetic field strength and signal quality. In this paper, we present…
Microstructure.jl is a Julia package designed for probabilistic estimation of tissue microstructural parameters from diffusion or combined diffusion-relaxometry MRI data. It provides a flexible and extensible framework for defining…
Axon diameter and myelin thickness affect the conduction velocity of action potentials in the nervous system. Imaging them non-invasively with MRI-based methods is thus valuable for studying brain microstructure and function. Electron…
Aims: This meta-analysis aimed to evaluate the diagnostic performance of echocardiographic parameters for cardiac amyloidosis (CA), with a focus on subtype stratification and comparisons with healthy controls. Methods and Results: A…
Magnetic resonance imaging of hyperpolarized (HP) [1-13C]pyruvate allows in-vivo assessment of metabolism and has translated into human studies across diseases at 15 centers worldwide. Consensus on best practice for multi-center studies is…
Background: Ultra-high-dose-rate (UHDR) radiation therapy has demonstrated promising potential in reducing toxicity to organs-at-risk (OARs). Proton therapy is uniquely positioned to deliver UHDR by leveraging the Bragg peak in conjunction…
Finite element analysis (FEA) forms the cornerstone of modeling cardiac biomechanics but is computationally expensive, limiting its clinical application for digital twin creation, which often requires tens to hundreds of simulations to…
T-wave alternans (TWA) is a potential marker for sudden cardiac death, but its reliable analysis is often constrained to noise-free environments, limiting its utility in real-world settings. We explore model-based T-wave estimation to…
This study aims to identify and parameterize the optimal survival curves for 33 fundamental microorganisms subject to UVC exposure through experimental measurements. We compile published data on UVC doses and corresponding survival…
Purpose: Phosphorus saturation-transfer experiments can quantify metabolic fluxes non-invasively. Typically, the forward flux through the creatine-kinase reaction is investigated by observing the decrease in phosphocreatine (PCr) after…
Purpose: Hyperpolarized imaging experiments have conflicting requirements of high spatial, temporal, and spectral resolution. Spectral-Spatial RF excitation has been shown to form an attractive magnetization-efficient method for…
Dynamic and precise measurement of cerebral blood flow velocity is crucial in neuroscience and the diagnosis of cerebrovascular diseases. Traditional color Doppler ultrasound can only measure the velocity component along the ultrasound…
Background: The intensity of the electric field applied to a brain tumor by electric field therapy is influenced by the position of the electrode array, which should be optimized based on the patient's head shape and tumor characteristics.…
Depolarization of circularly polarized light due to multiple scattering in turbid media provides size distributions of scatterer. Applied it to the biological tissues as turbid media, scatters correspond to cell nuclei, which is abnormally…
Purpose: Dynamic glucose enhanced (DGE) MRI studies employ chemical exchange saturation transfer (CEST) or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To…
Background: Deep learning has significantly advanced medical image analysis, with Vision Transformers (ViTs) offering a powerful alternative to convolutional models by modeling long-range dependencies through self-attention. However, ViTs…
Continuous blood pressure (BP) estimation via photoplethysmography (PPG) remains a significant challenge, particularly in providing comprehensive cardiovascular insights for hypertensive complications. This study presents a novel…
Imaging the human body's morphological and angiographic information is essential for diagnosing, monitoring, and treating medical conditions. Ultrasonography performs the morphological assessment of the soft tissue based on acoustic…