医学物理
This report relates to a study group hosted by the EPSRC funded network, Integrating data-driven BIOphysical models into REspiratory MEdicine (BIOREME), and supported by SofTMech and Innovate UK, Business Connect. The BIOREME network hosts…
Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…
Air-vented ionization chambers exposed to clinical radiation beams may suffer from recombination during the drift of the charge carriers towards the electrodes. Thus, dosimetry protocols recommend the use of a correction factor, usually…
Diffuse Correlation Spectroscopy (DCS) allows the label-free investigation of microvascular dynamics deep within living tissue. However, common implementations of DCS are currently limited to measurement depths of $\sim 1-1.5cm$, which can…
Bioimpedance is an extensively studied non-invasive technique with diverse applications in biomedicine. This comprehensive review delves into the foundational concepts, technical intricacies, and practical implementations of bioimpedance.…
Optical coherence elastography (OCE) is a powerful non-invasive imaging technique for high-resolution assessment of tissue elasticity and viscoelasticity. Accurate characterization of viscoelastic properties requires estimating shear wave…
Purpose: Ferumoxytal-enhanced 5D free-running whole heart CMR provides image quality comparable to CTA, but requires hours-long reconstruction time, preventing clinical usage. This study developed a variable projection augmented Lagrangian…
Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…
We present a method to shape a neutron beam and project any specified target image using a single universal patterned mask that is transversely displaced. The method relies on ``ghost projection'', which is a reversed form of classical…
The cardiovascular and ocular systems are intricately connected, with hemodynamic interactions playing a crucial role in both physiological regulation and pathological conditions. However, existing models often treat these systems…
Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, particularly in routine physical examinations where chest CT scans are…
Health disparities (differences in non-genetic conditions that influence health) can be associated with differences in burden of disease by groups within a population. Social determinants of health (SDOH) are domains such as health care…
Objective: Radiotherapy treatment planning is a time-consuming and potentially subjective process that requires the iterative adjustment of model parameters to balance multiple conflicting objectives. Recent advancements in frontier…
MRI signal acquisition with multiple coils in a phased array is nowadays commonplace. The use of multiple receiver coils increases the signal-to-noise ratio (SNR) and enables accelerated parallel imaging methods. Some of these methods, like…
Conventional tissue engineering methodologies frequently depend on pharmacological strategies to induce or expedite tissue repair. However, bioengineered strategies incorporating biophysical stimulation have emerged as promising…
Purpose: The fiber optical links in 850 nm band with Ge-doped multi-mode (MM) fibers are well developed for data transmission at 10 Gbps and higher. The applications in nuclear environments require radiation resistance. The characteristics…
Microdosimetry provides a superior characterization of the radiation field compared to conventional LET-based methodology, and for this reason it has become increasingly attractive for quality assurance in particle therapy. However, the…
Diffusion magnetic resonance imaging (dMRI) is pivotal for probing the microstructure of the rapidly-developing fetal brain. However, fetal motion during scans and its interaction with magnetic field inhomogeneities result in artifacts and…
Magnetomotive ultrasound (MMUS) using magnetic nanoparticle contrast agents has shown promise for thrombosis imaging and quantitative elastometry via magnetomotive resonant acoustic spectroscopy (MRAS). Young's modulus measurements of…
In orthodontic treatment, the biological response of the tooth, periodontal ligament, and bone complex to orthodontic force is crucial in influencing treatment outcomes. The challenge lies in accurately measuring, estimating, and predicting…