医学物理
Embolic stroke during cardiopulmonary bypass (CPB) is strongly influenced by cannula induced flow disturbances that govern emboli transport and aortic wall loading. This study quantifies how aortic cannula orientation affects embolic…
Dynamic total body positron emission tomography (TB-PET) makes it feasible to measure the kinetics of all organs in the body simultaneously which may lead to important applications in multi-organ disease and systems physiology. Since…
Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…
Access to magnetic resonance imaging (MRI) remains severely limited in low- and middle-income countries, especially in sub-Saharan Africa, despite rising rates of non-communicable diseases. Low-field MRI presents an affordable, locally…
Background Following changes in table tennis ball materials, offensive returns have become more important for initiating sustained topspin offense. However, using the backhand flick (BF) to return forehand short balls often increases the…
Paganin's method for image reconstruction in propagation-based phase-contrast X-ray imaging and tomography has enjoyed broad acceptance in recent years, with over one thousand publications citing its use. The present paper discusses…
This report summarizes changes in federal research funding to the medical physics community between FY24 and FY25. By linking the AAPM membership database with NIH RePORTER records, we quantified the distribution of NIH funding for projects…
Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…
Accurate visualization of interventional devices, such as medical needles, is essential for the safe and effective guidance of minimally invasive procedures. Ultrasound (US) imaging is widely used for needle guidance, but the…
This study evaluates the uncertainty in nanodosimetric calculations caused by variations in interaction cross sections within Monte Carlo Track Structure (MCTS) simulation codes. Nanodosimetry relies on accurately simulating particle…
Purpose: Pushing MRI speed further demands more spatially-encoded information captured per unit time, e.g., by superimposing additional field modulations during oversampled readout. However, this can introduce calibration errors and…
Purpose: To accelerate MRI further, rapid B0 field modulations can be applied during oversampled readout to capture additional physical information, e.g., Wave-CAIPI, FRONSAC, local B0 coils modulations. These methods, however, introduce…
Finite element (FE) simulations emulating transcatheter pulmonary valve (TPV) system deployment in patient-specific right ventricular outflow tracts (RVOT) assume material properties for the RVOT and adjacent tissues. Sensitivity of the…
Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…
There has been debate for over 70-years about whether active skeletal muscle is dynamically stable at lengths greater than its optimal length. The stability of computational muscle models is a critical issue, as it directly affects our…
Immunohistochemistry (IHC) has transformed clinical pathology by enabling the visualization of specific proteins within tissue sections. However, traditional IHC requires one tissue section per stain, exhibits section-to-section…
Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…
Inverse optimization (IO) algorithms are used in GYN HDR brachytherapy planning, with user parameter settings embedded in commercial TPS. To examine the dosimetric influence of hidden input parameters in three IO algorithms-IPSA, HIPO, and…
In radiation therapy (RT) treatment planning, multi-criteria optimization (MCO) supports efficient plan selection but is usually solved for population-based dosimetric criteria and ignores patient-specific biological risk, potentially…
Assigning individuals with hearing impairment to auditory profiles can support a better understanding of the causes and consequences of hearing loss and facilitate profile-based hearing-aid fitting. However, the factors influencing auditory…