医学物理
The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament, its mechanical behavior is very dependent on the type of loading (compressive vs. tensile…
Purpose: Photon-counting computed tomography (PCCT) shows promise for medical imaging in regards to material separation and imaging of multiple contrast agents. However, many PCCT setups are under development and are not optimized for…
Standard dual-energy computed tomography (CT) uses two different X-ray energies to obtain energy-dependent tissue attenuation information to allow quantitative material decomposition. The combined use of dual-energy CT and positron emission…
In this work, we propose a novel technique for in-vivo proton therapy range verification. This technique makes use of a small hadron tumour marker, $^{92}$Mo, implanted at a short known distance from the clinical treatment volume. Signals…
Muscle transfers are commonly performed to restore joint function after muscle tears. However, there are not many biomechanical studies of muscle transfers, with the available ones often limited to passive movements in anatomical planes.…
We assessed the predictive value of new radiomic features characterizing the lesion dissemination in baseline 18F-FDG PET and tested whether combining them with baseline metabolic tumour volume (MTV) could improve prediction of progression…
Dual-energy imaging is a clinically well-established technique that offers several advantages over conventional X-ray imaging. By performing measurements with two distinct X-ray spectra, differences in energy-dependent attenuation are…
The SIR model with spatially inhomogeneous infection rate is studied with numerical simulations in one, two, and three dimensions, considering the case that the infection spreads inhomogeneously in densely populated regions or hot spots. We…
Photoacoustic imaging develops very fast in recent years due to its superior performance in many preclinical and clinical applications. However, it is still in a developing stage, and a lot of experiments have to be performed in a…
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has affected countries all across the world, heavily burdening the medical infrastructure with the growing number of patients affected by the coronavirus…
We present the SIBIA (Scalable Integrated Biophysics-based Image Analysis) framework for joint image registration and biophysical inversion and we apply it to analyse MR images of glioblastomas (primary brain tumors). In particular, we…
Real-time MR-imaging has been clinically adapted for monitoring thermal therapies since it can provide on-the-fly temperature maps simultaneously with anatomical information. However, proton resonance frequency based thermometry of moving…
Compared with conventional single-energy computed tomography (CT), dual-energy CT (DECT) provides better material differentiation but most DECT imaging systems require dual full-angle projection data at different X-ray spectra. Relaxing the…
Dental laser has been developed recently and gradually replaced the conventional dental treatment methods, especially in dental caries removal. The utility of laser in dentistry contributes to reduce the pain during surgery and decrease the…
Reverse Shoulder Arthroplasty (RSA) has become a very common procedure for shoulder joint replacement, even for scenarios where an anatomical reconstruction would traditionally be used. In this study, we investigate joint reaction forces…
Three dimensional Polarized Light Imaging (3D-PLI) is an optical technique which allows mapping the spatial fiber architecture of fibrous postmortem tissues, at sub-millimeter resolutions. Here, we propose an analytical and fast approach to…
We found that the real time reverse transcription-polymerase chain reaction (RT-PCR) detection of viral RNA from sputum or nasopharyngeal swab has a relatively low positive rate in the early stage to determine COVID-19 (named by the World…
Leukocyte differential test is a widely performed clinical procedure for screening infectious diseases. Existing hematology analyzers require labor-intensive work and a panel of expensive reagents. Here we report an artificial-intelligence…
Compressed sensing (CS) computed tomography has been proven to be important for several clinical applications, such as sparse-view computed tomography (CT), digital tomosynthesis and interior tomography. Traditional compressed sensing…
ElectroCOrticoGraphy (ECoG) technology measures electrical activity in the human brain via electrodes placed directly on the cortical surface during neurosurgery. Through its capability to record activity at a fast temporal resolution, ECoG…