医学物理
In recent decades, developments in detectors for X-ray imaging have improved dose efficiency. This has been accomplished with for example, structured scintillators such as columnar CsI, or with direct detectors where the X rays are…
Mechanistic studies of pediatric asthma require objective measures of environmental exposure metrics correlated with physiological responses. Here we report a cloud-based wearable IoT sensor system which can measure an asthma patient's…
Knowledge of x-ray attenuation is essential for developing and evaluating x-ray imaging technologies. For instance, techniques to better characterize cysts at mammography screening would be highly desirable to reduce recalls, but the…
Measurements of breast density have the potential to improve the efficiency and reduce the cost of screening mammography through personalized screening. Breast density has traditionally been evaluated from the dense area in a mammogram, but…
Knowledge of x-ray attenuation is essential for developing and evaluating x-ray imaging technologies. In mammography, measurement of breast density, dose estimation, and differentiation between cysts and solid tumours are example…
Purpose: To develop a single-shot multi-slice T1 mapping method by combing simultaneous multi-slice (SMS) excitations, single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH) and a nonlinear model-based reconstruction method.…
Purpose: To develop a method that adaptively generates tiny dictionaries for joint T1-T2 mapping. Theory: This work breaks the bond between dictionary size and representation accuracy (i) by approximating the Bloch-response manifold by…
Knowledge of x-ray attenuation is essential for developing and evaluating x-ray imaging technologies. For instance, techniques to distinguish between cysts and solid tumours at mammography screening would be highly desirable to reduce…
Vascular networks can provide invaluable information about tumor angiogenesis. Ultrafast Doppler imaging enables ultrasound to image micro-vessels by applying tissue clutter filtering methods on the Spatio-temporal data obtained from…
Measures of vascular tortuosity--how curved and twisted a vessel is--are associated with a variety of vascular diseases. Consequently, measurements of vessel tortuosity that are accurate and comparable across modality, resolution, and size…
When listening to a sound source in everyday-life situations, typical movement behavior can lead to a mismatch between the direction of the head and the direction of interest. This could reduce the performance of directional algorithms, as…
Spectral imaging is an umbrella term for energy-resolved x-ray imaging in medicine. The technique makes use of the energy dependence of x-ray attenuation to either increase the contrast-to-noise ratio, or to provide quantitative image data…
Cao et al (2018) published an article on inverse planning based on dose-averaged linear energy transfer (LET). Their claim that the problem can be cast as a linear optimization model relies on an incorrect application of the Charnes-Cooper…
The linear optimization algorithm ART3+O introduced by Chen et al. (2010) can efficiently solve large scale inverse planning problems encountered in radiation therapy by iterative projection. Its major weakness is that it cannot guarantee…
Spherical matrix arrays arguably represent an advantageous tomographic detection geometry for non-invasive deep tissue mapping of vascular networks and oxygenation with volumetric optoacoustic tomography (VOT). Hybridization of VOT with…
We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model. The diffusion tensors are acquired using Diffusion Tensor Magnetic Resonance Imaging (DTI) from a…
This chapter reviews recent developments of generative adversarial networks (GAN)-based methods for medical and biomedical image synthesis tasks. These methods are classified into conditional GAN and Cycle-GAN according to the network…
Short and long-term stabilities of cementless implants are strongly determined by the interfacial load transfer between implants and bone tissue. Stress-shielding effects arise from shear stresses due to the difference of material…
Purpose: To compare the segmentation and detection performance of a deep learning model trained on a database of human-labelled clinical diffusion-weighted (DW) stroke lesions to a model trained on the same database enhanced with synthetic…
Purpose: To simulate the intravoxel incoherent perfusion magnetic resonance magnitude signal from the motion of blood particles in three realistic vascular network graphs from a mouse brain. Methods: In three networks generated from the…