医学物理
In this study we present a kinematic approach to modeling needle insertion into soft tissues. The kinematic approach allows the presentation of the problem as Dirichlet-type (i.e. driven by enforced motion of boundaries) and therefore…
Algorithmic X-ray scatter compensation is a desirable technique in flat-panel X-ray imaging and cone-beam computed tomography. State-of-the-art U-net based image translation approaches yielded promising results. As there are no physics…
Presbyopia, an age-related ocular disorder, is characterized by the loss in the accommodative abilities of the human ocular system and afflicts more than 1.8 billion people world-wide. Conventional methods of correcting presbyopia fragment…
Purpose: To show some preliminary results about the possibility to exploit a cardiovascular mathematical model - made patient-specific by noninvasive data routinely measured during ordinary clinical examinations - in order to obtain…
Heavy ions have varying effects on the target. The most important factor in comparing this effect is Linear Energy Transfer (LET). Protons and carbons are heavy ions with high LET. Since these ions lose energy through collisions as they…
The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two of the most characterized properties of the TME are acidosis and hypoxia, both of which are considered hallmarks of tumours as well as critical factors…
A multi-prism lens (MPL) is a refractive x-ray lens with one-dimensional focusing properties. If used as a pre-object collimator in a scanning system for medical x-ray imaging, it reduces the divergence of the radiation and improves on…
Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…
The nuclides inhaled during nuclear accidents usually cause internal contamination of the lungs with low activity. Although a parallel-hole imaging system, which is widely used in medical gamma cameras, has a high resolution and good image…
In our analysis, we show that what Cottenden et al. accomplish is the derivation of the ordinary capstan equation, and a solution to a dynamic membrane with both a zero-Poisson's ratio and a zero-mass density on a rigid right-circular cone.…
Multi-slat prompt-gamma camera is a promising tool for range monitoring during proton therapy. We report the results of a comprehensive simulation study analyzing the precision which is possible to reach with this camera in determination of…
Dual-energy subtraction imaging (DES) is a method to improve the detectability of contrast agents over a lumpy background. Two images, acquired at x-ray energies above and below an absorption edge of the agent material, are logarithmically…
Conventional energy filters for x-ray imaging are based on absorbing materials which attenuate low energy photons, sometimes combined with an absorption edge, thus also discriminating towards photons of higher energies. These filters are…
We propose a realistic model for the evolution of the COVID-19 pandemic subject to the lockdown and quarantine measures, which takes into account the time-delay for recovery or death processes. The dynamic equations for the entire process…
Contaminated water is increasingly linked to diseases worldwide, necessitating the safety evaluation of the sources of domestic and drinking water in every locality. The present study aimed to assess water safety in terms of lead (Pb),…
This paper presents an analytical design of an ultrasonic power transfer system based on piezoelectric micro-machined ultrasonic transducer (PMUT) for fully wireless brain implants in mice. The key steps like the material selection of each…
Quantitative metrics in lung computed tomography (CT) images have been widely used, often without a clear connection with physiology. This work proposes a patient-independent model for the estimation of well-aerated volume of lungs in CT…
Recently, artificial intelligence technologies and algorithms have become a major focus for advancements in treatment planning for radiation therapy. As these are starting to become incorporated into the clinical workflow, a major concern…
Anterior uveitis is the most common form of intraocular inflammation, and one of its main signs is the presence of white blood cells (WBCs) in the anterior chamber (AC). Clinically, the true composition of cells can currently only be…
Chromatic properties of the multi-prism and prism-array X-ray lenses (MPL and PAL) can potentially be utilized for efficient energy filtering and dose reduction in mammography. The line-shaped foci of the lenses are optimal for coupling to…