医学物理
A recent expert consensus found that non-standard reporting in MRS studies led to poor reproducibility. In order to address this, MRSinMRS guidelines were introduced; however, because of the disparate nomenclature and data formats, adoption…
Portable low-field magnetic resonance imaging (MRI) systems have gained renewed interest owing to their cost effectiveness and point-of-care imaging capabilities. Yet, portable MRI systems suffer from relatively low signal-to-noise ratio…
Cancer therapy for deep-seated tumors requires precise irradiation of a small target deep within the patient while minimizing radiation exposure to surrounding tissues. This can be accomplished with a round beam sharply converging towards a…
Frequently, transient changes in physiological signals, such as ECG morphology, precede or follow a rate change. Current methods for visualizing morphology allow only the tracking of preselected changes, severely limiting analytical…
Deep Brain Stimulation (DBS) is effective in treating neurological disorders but involves invasive surgery. Non-invasive DBS aims to overcome surgical risks by means of externally applied electromagnetic fields. In this work, we present a…
Radiation therapy is an important tool in the treatment of breast cancer and can play a crucial role in improving patient outcomes. For breast cancer, if the technique has been for a long time the use of 3DCRT, clinicians have seen the…
In the context of range monitoring for particle therapy, this study presents the first experimental results obtained with the TIARA detector using carbon-ion beams at the CNAO clinical center in Pavia, Italy. TIARA is based on the Prompt…
Contraction of the left ventricle of the heart increases aortic root blood pressure (P), diameter (D) and blood velocity (U). When contraction diminishes, all three properties decrease. These perturbations propagate down the systemic…
MRI measurements from a decade-old study of the physical properties of brain tissue observed a dynamic, pulsating fluid flow in the interstitial spaces of the brain attributed to the cardiac cycle. The effects of this cyclic flow pattern on…
Breastfeeding efficiency relies on coordinated tongue motion, sustained tissue contact and maintenance of an effective intraoral seal. Current assessments of seal formation mainly use local kinematic descriptors or pressure recordings,…
In 2020 we first described placental contractions, and we have now undertaken a study to characterise them and seek features that might automatically separate them from uterine contractions. We recruited 36 healthy pregnant women to undergo…
Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…
Accurate 3D dose calculation for Pencil Beam Scanning Proton Therapy (PBSPT) is typically performed with Monte Carlo (MC) engines, but their runtimes limit adaptive workflows and repeated evaluations. Current deep-learning proton dose…
Carbon-ion radiotherapy provides high dose conformity for lung cancer, but its benefit is limited by two sources of uncertainties: interplay between scanned beam delivery and tumor motion, and dose modulation from heterogeneous lung tissue.…
Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…
Purpose: This study aims to investigate the use of dynamic MRI to assess abdominal wall biomechanics before and after hernia surgery, considering that such evaluations can enhance our understanding of physiopathology and contribute to…
Metal objects pose a significant challenge in cone-beam computed tomography, as their strong and energy-dependent X-ray attenuation leads to inconsistent projections and severe streaking and shading artifacts in reconstructed images. These…
Metallic plating systems composed of titanium and its alloys remain the standard treatment for craniofacial bony fixation but may require secondary removal due to infection, implant migration, or discomfort. Thus, biodegradable metallic…
Distinguishing causal relationships from statistical correlations remains a fundamental challenge in clinical research, limiting the translation of observational findings into interventional treatment guidelines. Here we apply causal…
Purpose: Conventional MRI is relying on the assumption of the magnetic field being homogeneous in direction and amplitude. However, with the growing interest in portable, affordable point-of-care MRI systems, these assumptions do not…