医学物理
In conventional particle beam microscopy, knowledge of the beam current is essential for accurate micrograph formation and sample milling. This generally necessitates offline calibration of the instrument. In this work, we establish that…
This work summarizes the design, construction, initial performance evaluation and pilot clinical results of the IMAS system, a long axial field of view (FOV), also known as total-body (TB-), positron emission tomography (PET) prototype…
How the human brain adjusts fuel handling and its bioenergetic state during changing glucose levels remains difficult to assess noninvasively. In this study, we established an interleaved multinuclear 7 T MR spectroscopy protocol to track a…
This study conceptualizes electronic dose to water, which is the radiation energy imparted to a unit mass of water by electronic interactions. The new dosimetry framework excludes nuclear interactions and consequently associated corrections…
Depth-of-interaction (DOI) encoding is an effective strategy for reducing parallax error and preserving spatial resolution in positron emission tomography (PET), particularly in compact small-animal scanners. To enable efficient…
Standard 6 megavolt (MV) radiotherapy is limited by source size and secondary electron range to minimum radiological penumbra widths of ~2-3 mm. This study investigates sharper beams via upright radiotherapy with lower energies and extended…
The use of synthetic data has emerged as an essential tool in Magnetic Resonance Spectroscopy (MRS) research and applications, providing advantages for optimization of acquisition, software validation, deep learning applications, and…
Estimating brain microstructure has important applications in medicine and neuroscience. Diffusion-weighted magnetic resonance imaging enables measuring microstructure \textit{in vivo}. Conventional biophysical model fitting can be accurate…
Probabilistic evaluation improves the trade-off between target coverage and OAR sparing in IMPT but remains computationally demanding. This study proposes sparse probabilistic evaluation (SPE), a computationally efficient approach…
Daily or weekly cone-beam computed tomography (CBCT) is employed in image-guided radiotherapy (IGRT) for precise patient alignment. However, its clinical utility in quantitative tasks is hindered by severe artifacts and inaccurate Hounsfeld…
Purpose: Low-field MRI systems operate at single MHz-range frequencies, where signal losses are primarily dominated by thermal noise from the radio-frequency (RF) receive coils. Achieving operation close to this limit is essential for…
A wireless wearable Electrical Impedance Tomography (EIT) system has been developed utilizing the AD5933 chip to achieve real-time imaging of lung respiration. The system employs a voltage excitation method tailored to human impedance…
Conventional cardiovascular magnetic resonance (CMR) cine imaging relies on binning multiple heartbeats into a single cardiac cycle, which fails in arrhythmic patients where beat-to-beat variability causes motion artifacts and loss of…
Despite advancements in surgical techniques, hernia recurrence rates remain high, underscoring the need for improved understanding of abdominal wall behaviour. While surgeons are aware of many factors contributing to hernia occurrence (e.g…
Objective: Real-time adaptive proton range verification systems based on produced neutrons require accurate information on their non-isotropic momentum distributions within short times, for which Monte Carlo (MC) methods are too…
Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…
Diagnostic imaging procedure using ionizing radiation has been growing due to its enormous benefits. However, using ionizing radiation is also associated with harmful biological effects. Therefore it is important to take consideration on…
Radiological mapping plays a critical role in nuclear emergency response and environmental management activities. A radiation image, representing the spatial and intensity distribution of the radioactivity, is reconstructed from the…
Quantitative imaging is an important feature of spectral X-ray and CT systems, especially photon-counting CT (PCCT) imaging systems, which is achieved through material decomposition (MD) using spectral measurements. In this work, we present…
Tissue-engineered vascular grafts (TEVG) have shown promise in advancing vascular reconstructions. However, precise in vivo implantation is challenging, and it is unclear how deviations in location and size affect hemodynamics. This study…