医学物理
Adaptive radiation therapy (ART) seeks to maintain accurate dose delivery by monitoring anatomical changes during treatment and modifying plans accordingly, yet commonly used approaches for estimating cumulative dose rely on heuristic,…
The development of deep learning methods for magnetic resonance spectroscopy (MRS) is often hindered by limited availability of large, high-quality training datasets. While physics-based simulations are commonly used to mitigate this…
Background: Commercially available ionization chambers (ICs) exposed to ultra-high dose per pulse (UHDP) exhibit deviations from a linear dose response due to volume recombination. Simulation models have been developed to describe the…
The problem of optimization of propagation-based phase-contrast imaging setups is considered in the case of projection X-ray imaging and three-dimensional tomography with phase retrieval. For two-dimensional imaging, a simple model for a…
This work aims to overcome an assumption of conventional MR simulators: Individual isochromats should be simulated individually. To reduce the computational times of MR simulation, a new simulation method using grouped isochromats is…
Self-powered intracardiac implant devices show great promise for future clinical applications due to their extended operational lifespan and the potential to reduce the need for high-risk repeat surgeries. This study investigates the…
Preterm birth is associated with premature cervical remodeling, yet current clinical assessments cannot detect the underlying microstructural changes in collagen organization. We apply imaging Mueller polarimetry to murine cervical tissue…
Curation is a significant barrier to using 'big data' radiotherapy planning databases of 100,000+ patients. Anatomic site stratification is essential for downstream analyses, but current methods rely on inconsistent plan labels or target…
We evaluated the viability of using a Large Language Model (LLM) to extract patient-specific specific toxicity and progression outcomes from unstructured radiology reports. We retrospectively extracted 160 follow-up CT and PET/CT electronic…
In this study, polyurethane-films loaded diclofenac were used to analyze the drug release kinetics and mechanisms. For this purpose, the experimental procedures were developed under static and dynamic conditions with different initial drug…
Although the circulatory system functions as a continuous source of physiological data, contemporary diagnostics remain bound to intermittent, time-delayed assessments. To resolve this, we present a framework for ubiquitous hematological…
In this study, we developed a UV-tape-assisted laser patterning (UT-Laser) technique that enables the simple transfer-based formation of wiring with line widths below 200 $\mu$m onto textile substrates. With the rapid advancement of…
The inherently slow acquisition speed of MRI makes abdominal imaging highly sensitive to respiratory motion artifacts. Since the early days of MRI, the development of respiratory motion compensation has been an active research topic, and…
The relationship between vascular morphology and hemodynamics is fundamental to understanding the natural history of cerebral aneurysms (CAs). While global geometric indices have been widely studied, the local interaction between luminal…
Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…
Background: Brain maturation and aging involve significant microstructural changes, resulting in functional and cognitive alterations. Quantitative MRI (qMRI) can measure this evolution, distinguishing the physiological effects of normal…
Objective: Radiolytic oxygen depletion (ROD) may play a role in the sparing of cells irradiated with ultra-high dose rates. Different methods have been used to quantify the effect of ROD during FLASH irradiation on cell survival, typically…
The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are…
Optoacoustic imaging technologies require fast and accurate signal pre-processing algorithms to enable widespread deployment in clinical and home-care settings. However, they still rely on the Discrete Fourier Transform (DFT) as the default…
Objective: Time-difference electrical impedance tomography (EIT) is gaining widespread use for bedside lung monitoring in intensive care patients suffering from lung-related diseases. It involves collecting voltage measurements from…