医学物理
Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…
Three-dimensional digital subtraction angiography (3D-DSA) is a widely adopted technique for clinical evaluation of contrast-enhanced vasculatures. The distribution of a contrast agent such as iodine is often estimated via temporal…
Combinations of spectroscopic analysis and microscopic techniques are used across many disciplines of scientific research, including material science, chemistry and biology. X-ray spectromicroscopy, in particular, is a powerful tool used…
Emerging methods of x-ray imaging that capture phase and dark-field effects are equipping medicine with complementary sensitivity to conventional radiography. These methods are being applied over a wide range of scales, from virtual…
Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), a new imaging method…
Purpose: Magnetization transfer saturation (MTsat) mapping is commonly used to examine the macromolecular content of brain tissue. This study compared variable flip angle (VFA) T1 mapping against compressed sensing (cs)MP2RAGE T1 mapping…
Pancreatic diseases are difficult to treat with high doses of radiation, as they often present both periodic and aperiodic deformations. Nevertheless, we expect that these difficulties can be overcome, and treatment results may be improved…
We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and…
Purpose: Determine the correct mathematical phase description for balanced steady-state free precession (bSSFP) signals in multicompartment systems. Theory and Methods: Based on published bSSFP signal models, two distinct phase descriptions…
The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…
Online dose calculations before radiation treatment have applications in dose delivery verification, plan adaptation, and treatment planning. We propose a novel CBCT imaging pipeline to enhance accuracy. Our approach aims to improve HU…
Purpose: This work aims to address the limitations faced by researchers in developing and sharing new MRI sequences by implementing an interpreter for the open-source MRI pulse sequence format, Pulseq, on a Philips MRI scanner. Methods: The…
Objective: Breast tissue is mainly a mixture of adipose and fibro-glandular tissue. Cancer risk and risk of undetected breast cancer increases with the amount of glandular tissue in the breast. Therefore, radiologists must report the total…
Purpose. NTCP modelling is rapidly embracing DL methods as the need to include spatial dose information is acknowledged. Finding the most appropriate way of combining radiation dose distribution images and clinical data involves technical…
The present study investigates perceived comfort and whole-body vibration transmissibility in intensive repetitive pitch exposure representing a bumpy ride. Three sitting strategies (preferred, erect, and slouched) were evaluated for…
Objective: Quantitative $T_1\rho$ imaging has potential for assessment of biochemical alterations of liver pathologies. Deep learning methods have been employed to accelerate quantitative $T_1\rho$ imaging. To employ artificial…
Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for biomedical detection. However, it is challenging to accurately quantify metabolites with proton MRS due to serious overlaps of metabolite signals, imperfections…
Vascular imaging is critical for understanding human health and disease. Most established non-contact and label-free optical techniques capture predominantly structural information about vasculature. However, in many pathologies, functional…
This study compares electric field and temperature distributions between non-invasive and invasive tumor treatment fields (TTFields). We employ four-layer spherical head models, representing the scalp, skull, cerebrospinal fluid, and brain,…
Purpose: To introduce the concept of using large language models (LLMs) to re-label structure names in accordance with the American Association of Physicists in Medicine (AAPM) Task Group (TG)-263 standard, and to establish a benchmark for…