医学物理
Nanoporous membranes have gained considerable interest in drug delivery1, ion transportation2, micro/nanofluidics3, molecular sensing4, and separation science5. Artificial kidneys, also known as dialyzers, reject pathogens and other…
$Objective:$ Information on the metabolism of tissues in both healthy and diseased states plays a significant role in the detection and understanding of tumors, neurodegenerative diseases, diabetes, and other metabolic disorders.…
Since the invention of modern CT systems, metal artifacts have been a persistent problem. Due to increased scattering, amplified noise, and insufficient data collection, it is more difficult to suppress metal artifacts in cone-beam CT,…
There is an important need for methods to process myocardial perfusion imaging (MPI) SPECT images acquired at lower radiation dose and/or acquisition time such that the processed images improve observer performance on the clinical task of…
Preclinical research and organ-dedicated applications require high-resolution positron emission tomography (PET) detectors to visualize small structures and understand biological processes at a finer level of detail. Current commercial…
Purpose: We implemented the blip-up, blip-down circular echo planar imaging (BUDA-cEPI) sequence with readout and phase partial Fourier to reduced off-resonance effect and T2* blurring. BUDA-cEPI reconstruction with S-based low-rank…
This work aims efficiently estimating the posterior distribution of kinetic parameters for dynamic positron emission tomography (PET) imaging given a measurement of time of activity curve. Considering the inherent information loss from…
Ultrasound Localization Microscopy (ULM) has recently enabled the mapping of the cerebral vasculature in vivo with a resolution ten times smaller than the wavelength used, down to ten microns. However, with frame rates up to 20.000 frames…
The development of neurologically active drugs faces a challenge in treating brain diseases due to the blood-brain barrier's impermeability. High-intensity focused ultrasound can open the barrier in a targeted manner, expanding treatment…
Radiotherapy aims to deliver a prescribed dose to the tumor while sparing neighboring organs at risk (OARs). Increasingly complex treatment techniques such as volumetric modulated arc therapy (VMAT), stereotactic radiosurgery (SRS),…
Background: Proton arc therapy is an emerging radiation therapy technique where either the gantry or the patient continuously rotates during the irradiation treatment. One of the perceived advantages of proton arc therapy is the reduced…
Tomography has had an important impact on the physical, biological, and medical sciences. To date, most tomographic applications have been focused on 3D scalar reconstructions. However, in some crucial applications, vector tomography is…
The purpose of this study was to quantitatively evaluate the performance of different simultaneous spatial and temporal regularizers in liver perfusion studies using low-dose dynamic contrast-enhanced computed tomography (DCE-CT). A digital…
Ultrasound computed tomography (USCT) is an emerging medical imaging modality that holds great promise for improving human health. Full-waveform inversion (FWI)-based image reconstruction methods account for the relevant wave physics to…
Nuclear Magnetic Resonance (NMR) spectroscopy is an important bio-engineering tool to determine the metabolic concentrations, molecule structures and so on. The data acquisition time, however, is very long in multi-dimensional NMR. To…
Recent studies have documented ocular changes in dementia patients, especially Alzheimer Disease (AD). In this study, we explored the change of eye size and eye shape in dementia, including AD patients. The eyeball volume and diameters were…
We present simulations of whole-body low-dose time-of-flight positron emission tomography (TOF-PET) based on the direct surface production [1] by 511 keV gamma rays of energetic electrons via the Photo-electric and Compton Effects,…
Previous initial research has already been carried out to propose speech-based BCI using brain signals (e.g. non-invasive EEG and invasive sEEG / ECoG), but there is a lack of combined methods that investigate non-invasive brain,…
We present the first study to investigate Large Language Models (LLMs) in answering radiation oncology physics questions. Because popular exams like AP Physics, LSAT, and GRE have large test-taker populations and ample test preparation…
The MR-Linac can enable real-time radiotherapy adaptation. However, real-time image acquisition is restricted to 2D to obtain sufficient spatial resolution, hindering accurate 3D segmentation. By reducing spatial resolution fast 3D imaging…